PDB: AF-P51955 — NEK NEK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P51955-K1A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK NEK2 NEK2_HUMAN AF-P51955-K1A P51955 1 279 445.0 No_ligand No_ligand Active DFGin 6.869 14.633 BLAminus -133.95, -173.4 54.79, 72.42 -82.83, 18.74 289.02, 77.16 -61.4, -26.12 out-in out 10.002 Saltbr-in 3.279 HRD-in -72.13, -45.55 64.71, 0.38 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.02, 153.79 APE9-dihe-na 121.29, 162.72 APE8-dihe-in -74.75, 126.9 APE8-rot-in 300.51 APE67-dihe-in -70.7, -19.6 -51.47, -35.98 APE12-dist-in 8.99 APE11-dist-in 12.023 APE10-dist-in 6.045 APE9-dist-in 3.386 None None None AF2 -1.0 1.0 1.0 A 279 279 0 0 0 0 [[8, 271]] 1.0 AF-P51955-K1 NEK_NEK2_HUMAN NEK 7.7e-110 372.3 1 256 256 158 159 160 162 164 37 55 59 138 140 139 141 198 186 181 180 179 178 177 176 175 87 Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN AF-P51955-K3A P51955 1 279 445.0 No_ligand No_ligand Active DFGin 6.974 14.518 BLAminus -137.03, -171.55 54.92, 64.89 -76.15, 14.43 291.41, 82.24 -62.84, -23.1 in-in in 9.438 Saltbr-in 3.249 HRD-in -75.06, -47.19 67.7, -5.95 in-in-in SNCiii in-in ActLoopNT-in 2.851 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.44, 154.63 APE9-dihe-na 115.59, 177.84 APE8-dihe-in -86.96, 123.76 APE8-rot-in 298.85 APE67-dihe-in -69.6, -21.35 -53.86, -31.33 APE12-dist-in 9.054 APE11-dist-in 11.879 APE10-dist-in 5.958 APE9-dist-in 3.308 None None None AF2 -1.0 1.0 1.0 A 279 279 0 0 0 0 [[8, 271]] 1.0 AF-P51955-K3 NEK_NEK2_HUMAN NEK 7.7e-110 372.3 1 256 256 158 159 160 162 164 37 55 59 138 140 139 141 198 186 181 180 179 178 177 176 175 87 Serine/threonine-protein kinase Nek2

PDB: AF-P51955 — NEK NEK2_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P51955-K1A

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
NEK NEK2 NEK2_HUMAN AF-P51955-K1A P51955 1 279 445.0 No_ligand No_ligand Active DFGin 6.869 14.633 BLAminus -133.95, -173.4 54.79, 72.42 -82.83, 18.74 289.02, 77.16 -61.4, -26.12 out-in out 10.002 Saltbr-in 3.279 HRD-in -72.13, -45.55 64.71, 0.38 in-in-in SNCiii in-in ActLoopNT-in 2.84 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.02, 153.79 APE9-dihe-na 121.29, 162.72 APE8-dihe-in -74.75, 126.9 APE8-rot-in 300.51 APE67-dihe-in -70.7, -19.6 -51.47, -35.98 APE12-dist-in 8.99 APE11-dist-in 12.023 APE10-dist-in 6.045 APE9-dist-in 3.386 None None None AF2 -1.0 1.0 1.0 A 279 279 0 0 0 0 [[8, 271]] 1.0 AF-P51955-K1 Homo sapiens NEK_NEK2_HUMAN NEK 7.7e-110 372.3 1 256 256 158 159 160 162 164 37 55 59 138 140 139 141 198 186 181 180 179 178 177 176 175 87 Serine/threonine-protein kinase Nek2
NEK NEK2 NEK2_HUMAN AF-P51955-K3A P51955 1 279 445.0 No_ligand No_ligand Active DFGin 6.974 14.518 BLAminus -137.03, -171.55 54.92, 64.89 -76.15, 14.43 291.41, 82.24 -62.84, -23.1 in-in in 9.438 Saltbr-in 3.249 HRD-in -75.06, -47.19 67.7, -5.95 in-in-in SNCiii in-in ActLoopNT-in 2.851 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -139.44, 154.63 APE9-dihe-na 115.59, 177.84 APE8-dihe-in -86.96, 123.76 APE8-rot-in 298.85 APE67-dihe-in -69.6, -21.35 -53.86, -31.33 APE12-dist-in 9.054 APE11-dist-in 11.879 APE10-dist-in 5.958 APE9-dist-in 3.308 None None None AF2 -1.0 1.0 1.0 A 279 279 0 0 0 0 [[8, 271]] 1.0 AF-P51955-K3 Homo sapiens NEK_NEK2_HUMAN NEK 7.7e-110 372.3 1 256 256 158 159 160 162 164 37 55 59 138 140 139 141 198 186 181 180 179 178 177 176 175 87 Serine/threonine-protein kinase Nek2

PDB: AF-P51955 — NEK NEK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name