| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA3-1 | KS6A3_HUMAN | AF-P51812-K1A | P51812 | 60 | 335 | 740.0 | No_ligand | No_ligand | Active | DFGin | 6.7641 | 14.3648 | BLAminus | -128.08, -168.93 | 44.14, 64.08 | -76.47, 13.22 | 289.9, 79.47 | -63.08, -17.42 | in-in | in | 8.8638 | Saltbr-in | 2.6727 | HRD-in | -82.22, -48.58 | 63.74, 10.13 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8886 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.28, 165.34 | APE9-dihe-na | 113.22, 171.27 | APE8-dihe-in | -72.62, 129.88 | APE8-rot-in | 293.52 | APE67-dihe-in | -60.98, -26.44 | -58.38, -41.01 | APE12-dist-in | 8.4759 | APE11-dist-in | 11.4135 | APE10-dist-in | 5.6812 | APE9-dist-in | 3.5357 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 276.0 | 276.0 | 0 | 28 | 28 | 0 | [[68, 327], [422, 679]] | 2.0 | AF-P51812-K1 | AGC_RPS6KA3-1_HUMAN | AGC | 1.5e-97 | 331.7 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | AF-P51812-K3A | P51812 | 60 | 335 | 740.0 | No_ligand | No_ligand | Active | DFGin | 6.4993 | 14.1621 | BLAminus | -131.58, -177.03 | 51.85, 64.94 | -73.26, 9.93 | 296.53, 86.04 | -63.15, -12.88 | in-in | in | 8.7855 | Saltbr-in | 2.6275 | HRD-in | -83.1, -49.32 | 68.04, 9.8 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8716 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -154.96, 166.11 | APE9-dihe-na | 108.7, 179.24 | APE8-dihe-in | -85.77, 132.92 | APE8-rot-in | 303.81 | APE67-dihe-in | -62.2, -27.77 | -65.91, -38.69 | APE12-dist-in | 8.3892 | APE11-dist-in | 11.4298 | APE10-dist-in | 5.6727 | APE9-dist-in | 3.3621 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 276.0 | 276.0 | 0 | 28 | 28 | 0 | [[68, 327], [422, 679]] | 2.0 | AF-P51812-K3 | AGC_RPS6KA3-1_HUMAN | AGC | 1.5e-97 | 331.7 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| CAMK | RPS6KA3-2 | KS6A3_HUMAN | AF-P51812-K2A | P51812 | 414 | 687 | 740.0 | No_ligand | No_ligand | Active | DFGin | 6.7298 | 14.1683 | BLAminus | -125.79, -177.39 | 55.82, 66.57 | -75.99, 24.17 | 288.05, 79.68 | -59.14, -33.85 | in-in | in | 8.8374 | Saltbr-in | 2.7385 | HRD-in | -74.61, -43.89 | 70.54, -1.34 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9872 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -134.4, 128.02 | APE9-dihe-na | -170.43, 160.5 | APE8-dihe-in | -95.56, 132.02 | APE8-rot-in | 299.76 | APE67-dihe-in | -73.03, -14.52 | -50.87, -42.54 | APE12-dist-in | 8.8657 | APE11-dist-in | 10.8421 | APE10-dist-in | 4.9928 | APE9-dist-in | 4.1216 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[68, 327], [422, 679]] | 2.0 | AF-P51812-K2 | CAMK_RPS6KA3-2_HUMAN | CAMK | 3.1e-87 | 298.1 | 1.0 | 256.0 | 256.0 | 560 | 561 | 562 | 564 | 566 | 451 | 463 | 467 | 536 | 538 | 537 | 539.0 | 600 | 588 | 583 | 582 | 581 | 580 | 579 | 578 | 577 | 494 | Ribosomal protein S6 kinase alpha-3 |
| CAMK | RPS6KA3-2 | KS6A3_HUMAN | AF-P51812-K4A | P51812 | 414 | 687 | 740.0 | No_ligand | No_ligand | Active | DFGin | 6.4354 | 14.3644 | BLAminus | -132.83, -176.2 | 53.82, 63.58 | -70.94, 24.31 | 287.91, 81.74 | -68.64, -24.12 | in-in | in | 8.9142 | Saltbr-in | 2.7514 | HRD-in | -78.93, -40.76 | 66.85, 11.06 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9108 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -132.71, 127.25 | APE9-dihe-na | -171.64, 159.25 | APE8-dihe-in | -90.92, 129.8 | APE8-rot-in | 301.02 | APE67-dihe-in | -76.65, -14.51 | -52.74, -40.79 | APE12-dist-in | 8.6566 | APE11-dist-in | 10.9774 | APE10-dist-in | 5.0713 | APE9-dist-in | 4.2444 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[68, 327], [422, 679]] | 2.0 | AF-P51812-K4 | CAMK_RPS6KA3-2_HUMAN | CAMK | 3.1e-87 | 298.1 | 1.0 | 256.0 | 256.0 | 560 | 561 | 562 | 564 | 566 | 451 | 463 | 467 | 536 | 538 | 537 | 539.0 | 600 | 588 | 583 | 582 | 581 | 580 | 579 | 578 | 577 | 494 | Ribosomal protein S6 kinase alpha-3 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA3-1 | KS6A3_HUMAN | AF-P51812-K1A | P51812 | 60 | 335 | 740.0 | No_ligand | No_ligand | Active | DFGin | 6.7641 | 14.3648 | BLAminus | -128.08, -168.93 | 44.14, 64.08 | -76.47, 13.22 | 289.9, 79.47 | -63.08, -17.42 | in-in | in | 8.8638 | Saltbr-in | 2.6727 | HRD-in | -82.22, -48.58 | 63.74, 10.13 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8886 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.28, 165.34 | APE9-dihe-na | 113.22, 171.27 | APE8-dihe-in | -72.62, 129.88 | APE8-rot-in | 293.52 | APE67-dihe-in | -60.98, -26.44 | -58.38, -41.01 | APE12-dist-in | 8.4759 | APE11-dist-in | 11.4135 | APE10-dist-in | 5.6812 | APE9-dist-in | 3.5357 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 276.0 | 276.0 | 0 | 28 | 28 | 0 | [[68, 327], [422, 679]] | 2.0 | AF-P51812-K1 | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 1.5e-97 | 331.7 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| AGC | RPS6KA3-1 | KS6A3_HUMAN | AF-P51812-K3A | P51812 | 60 | 335 | 740.0 | No_ligand | No_ligand | Active | DFGin | 6.4993 | 14.1621 | BLAminus | -131.58, -177.03 | 51.85, 64.94 | -73.26, 9.93 | 296.53, 86.04 | -63.15, -12.88 | in-in | in | 8.7855 | Saltbr-in | 2.6275 | HRD-in | -83.1, -49.32 | 68.04, 9.8 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8716 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -154.96, 166.11 | APE9-dihe-na | 108.7, 179.24 | APE8-dihe-in | -85.77, 132.92 | APE8-rot-in | 303.81 | APE67-dihe-in | -62.2, -27.77 | -65.91, -38.69 | APE12-dist-in | 8.3892 | APE11-dist-in | 11.4298 | APE10-dist-in | 5.6727 | APE9-dist-in | 3.3621 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 276.0 | 276.0 | 0 | 28 | 28 | 0 | [[68, 327], [422, 679]] | 2.0 | AF-P51812-K3 | Homo sapiens | AGC_RPS6KA3-1_HUMAN | AGC | 1.5e-97 | 331.7 | 1.0 | 260.0 | 260.0 | 210 | 211 | 212 | 214 | 216 | 100 | 118 | 122 | 190 | 192 | 191 | 193.0 | 250 | 238 | 233 | 232 | 231 | 230 | 229 | 228 | 227 | 148 | Ribosomal protein S6 kinase alpha-3 |
| CAMK | RPS6KA3-2 | KS6A3_HUMAN | AF-P51812-K2A | P51812 | 414 | 687 | 740.0 | No_ligand | No_ligand | Active | DFGin | 6.7298 | 14.1683 | BLAminus | -125.79, -177.39 | 55.82, 66.57 | -75.99, 24.17 | 288.05, 79.68 | -59.14, -33.85 | in-in | in | 8.8374 | Saltbr-in | 2.7385 | HRD-in | -74.61, -43.89 | 70.54, -1.34 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9872 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -134.4, 128.02 | APE9-dihe-na | -170.43, 160.5 | APE8-dihe-in | -95.56, 132.02 | APE8-rot-in | 299.76 | APE67-dihe-in | -73.03, -14.52 | -50.87, -42.54 | APE12-dist-in | 8.8657 | APE11-dist-in | 10.8421 | APE10-dist-in | 4.9928 | APE9-dist-in | 4.1216 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[68, 327], [422, 679]] | 2.0 | AF-P51812-K2 | Homo sapiens | CAMK_RPS6KA3-2_HUMAN | CAMK | 3.1e-87 | 298.1 | 1.0 | 256.0 | 256.0 | 560 | 561 | 562 | 564 | 566 | 451 | 463 | 467 | 536 | 538 | 537 | 539.0 | 600 | 588 | 583 | 582 | 581 | 580 | 579 | 578 | 577 | 494 | Ribosomal protein S6 kinase alpha-3 |
| CAMK | RPS6KA3-2 | KS6A3_HUMAN | AF-P51812-K4A | P51812 | 414 | 687 | 740.0 | No_ligand | No_ligand | Active | DFGin | 6.4354 | 14.3644 | BLAminus | -132.83, -176.2 | 53.82, 63.58 | -70.94, 24.31 | 287.91, 81.74 | -68.64, -24.12 | in-in | in | 8.9142 | Saltbr-in | 2.7514 | HRD-in | -78.93, -40.76 | 66.85, 11.06 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9108 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -132.71, 127.25 | APE9-dihe-na | -171.64, 159.25 | APE8-dihe-in | -90.92, 129.8 | APE8-rot-in | 301.02 | APE67-dihe-in | -76.65, -14.51 | -52.74, -40.79 | APE12-dist-in | 8.6566 | APE11-dist-in | 10.9774 | APE10-dist-in | 5.0713 | APE9-dist-in | 4.2444 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 274.0 | 274.0 | 0 | 28 | 28 | 0 | [[68, 327], [422, 679]] | 2.0 | AF-P51812-K4 | Homo sapiens | CAMK_RPS6KA3-2_HUMAN | CAMK | 3.1e-87 | 298.1 | 1.0 | 256.0 | 256.0 | 560 | 561 | 562 | 564 | 566 | 451 | 463 | 467 | 536 | 538 | 537 | 539.0 | 600 | 588 | 583 | 582 | 581 | 580 | 579 | 578 | 577 | 494 | Ribosomal protein S6 kinase alpha-3 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|