PDB: AF-P49336 — CMGC CDK8_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P49336-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK8 CDK8_HUMAN AF-P49336-K1A P49336 12 343 464.0 No_ligand No_ligand Active DFGin 6.9313 15.6629 BLAminus -128.17, 177.28 55.68, 59.43 -72.54, 15.56 300.04, 114.68 -62.04, -32.39 in-in in 9.1654 Saltbr-in 2.8975 HRD-in -73.5, -51.19 62.86, 10.05 in-in-in SNCiii in-in ActLoopNT-in 2.8327 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.05, 164.39 APE9-dihe-na 83.32, 124.4 APE8-dihe-in -52.27, 134.37 APE8-rot-in 287.61 APE67-dihe-in -65.17, -26.48 -44.23, -41.35 APE12-dist-in 12.0588 APE11-dist-in 11.607 APE10-dist-in 5.8083 APE9-dist-in 3.4091 None None None AF2 -1.0 1.0 1.0 A 332.0 332.0 0 31 31 0 [[22, 335]] 1.0 AF-P49336-K1 CMGC_CDK8_HUMAN CMGC 2.9e-82 282.3 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN AF-P49336-K3A P49336 12 343 464.0 No_ligand No_ligand Active DFGin 7.0585 14.4146 BLAminus -125.11, 179.05 58.06, 66.16 -75.42, 13.63 298.43, 116.53 -58.59, -38.0 in-in in 9.222 Saltbr-in 2.7201 HRD-in -77.81, -49.38 63.32, 9.66 in-in-in SNCiii in-in ActLoopNT-in 2.8729 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.07, 166.88 APE9-dihe-na 60.71, 128.33 APE8-dihe-in -54.75, 135.42 APE8-rot-in 297.36 APE67-dihe-in -67.37, -15.46 -44.59, -50.0 APE12-dist-in 12.5614 APE11-dist-in 10.811 APE10-dist-in 6.5807 APE9-dist-in 3.286 None None None AF2 -1.0 1.0 1.0 A 332.0 332.0 0 31 31 0 [[22, 335]] 1.0 AF-P49336-K3 CMGC_CDK8_HUMAN CMGC 2.9e-82 282.3 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8

PDB: AF-P49336 — CMGC CDK8_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-P49336-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK8 CDK8_HUMAN AF-P49336-K1A P49336 12 343 464.0 No_ligand No_ligand Active DFGin 6.9313 15.6629 BLAminus -128.17, 177.28 55.68, 59.43 -72.54, 15.56 300.04, 114.68 -62.04, -32.39 in-in in 9.1654 Saltbr-in 2.8975 HRD-in -73.5, -51.19 62.86, 10.05 in-in-in SNCiii in-in ActLoopNT-in 2.8327 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -95.05, 164.39 APE9-dihe-na 83.32, 124.4 APE8-dihe-in -52.27, 134.37 APE8-rot-in 287.61 APE67-dihe-in -65.17, -26.48 -44.23, -41.35 APE12-dist-in 12.0588 APE11-dist-in 11.607 APE10-dist-in 5.8083 APE9-dist-in 3.4091 None None None AF2 -1.0 1.0 1.0 A 332.0 332.0 0 31 31 0 [[22, 335]] 1.0 AF-P49336-K1 Homo sapiens CMGC_CDK8_HUMAN CMGC 2.9e-82 282.3 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8
CMGC CDK8 CDK8_HUMAN AF-P49336-K3A P49336 12 343 464.0 No_ligand No_ligand Active DFGin 7.0585 14.4146 BLAminus -125.11, 179.05 58.06, 66.16 -75.42, 13.63 298.43, 116.53 -58.59, -38.0 in-in in 9.222 Saltbr-in 2.7201 HRD-in -77.81, -49.38 63.32, 9.66 in-in-in SNCiii in-in ActLoopNT-in 2.8729 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -132.07, 166.88 APE9-dihe-na 60.71, 128.33 APE8-dihe-in -54.75, 135.42 APE8-rot-in 297.36 APE67-dihe-in -67.37, -15.46 -44.59, -50.0 APE12-dist-in 12.5614 APE11-dist-in 10.811 APE10-dist-in 6.5807 APE9-dist-in 3.286 None None None AF2 -1.0 1.0 1.0 A 332.0 332.0 0 31 31 0 [[22, 335]] 1.0 AF-P49336-K3 Homo sapiens CMGC_CDK8_HUMAN CMGC 2.9e-82 282.3 5.0 301.0 297.0 172 173 174 176 178 52 66 70 148 150 149 151.0 216 203 198 197 196 195 194 193 192 98 Cyclin-dependent kinase 8

PDB: AF-P49336 — CMGC CDK8_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name