PDB: AF-O76039 — CMGC CDKL5_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O76039-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDKL5 CDKL5_HUMAN AF-O76039-K1A O76039 5 305 960.0 No_ligand No_ligand Active DFGin 6.6164 14.6609 BLAminus -136.07, 177.68 60.87, 71.76 -82.76, 16.96 285.64, 76.61 -59.9, -36.88 in-in in 8.899 Saltbr-in 2.9103 HRD-in -74.11, -46.73 62.28, 16.59 in-in-in SNCiii in-in ActLoopNT-in 2.9814 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.14, 157.89 APE9-dihe-na 63.24, 141.46 APE8-dihe-in -59.26, 134.49 APE8-rot-in 301.23 APE67-dihe-in -63.18, -25.69 -49.58, -43.74 APE12-dist-in 13.2265 APE11-dist-in 10.6332 APE10-dist-in 6.2445 APE9-dist-in 3.1592 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 29 29 0 [[13, 297]] 1.0 AF-O76039-K1 CMGC_CDKL5_HUMAN CMGC 3e-85 292.0 1.0 300.0 300.0 152 153 154 156 158 42 60 64 132 134 133 135.0 193 181 176 175 174 173 172 171 170 90 Cyclin-dependent kinase-like 5
CMGC CDKL5 CDKL5_HUMAN AF-O76039-K3A O76039 5 305 960.0 No_ligand No_ligand Active DFGin 6.3799 14.5687 BLAminus -135.21, -179.4 59.2, 71.28 -81.53, 13.86 287.9, 78.93 -57.07, -40.59 in-in in 8.5058 Saltbr-in 2.7505 HRD-in -76.53, -47.61 66.44, 2.41 in-in-in SNCiii in-in ActLoopNT-in 2.9172 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.17, 153.4 APE9-dihe-na 60.48, 150.09 APE8-dihe-in -58.09, 134.7 APE8-rot-in 295.86 APE67-dihe-in -61.87, -22.51 -50.82, -39.79 APE12-dist-in 12.3194 APE11-dist-in 10.21 APE10-dist-in 6.0565 APE9-dist-in 3.7474 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 29 29 0 [[13, 297]] 1.0 AF-O76039-K3 CMGC_CDKL5_HUMAN CMGC 3e-85 292.0 1.0 300.0 300.0 152 153 154 156 158 42 60 64 132 134 133 135.0 193 181 176 175 174 173 172 171 170 90 Cyclin-dependent kinase-like 5

PDB: AF-O76039 — CMGC CDKL5_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% AF-O76039-K1A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDKL5 CDKL5_HUMAN AF-O76039-K1A O76039 5 305 960.0 No_ligand No_ligand Active DFGin 6.6164 14.6609 BLAminus -136.07, 177.68 60.87, 71.76 -82.76, 16.96 285.64, 76.61 -59.9, -36.88 in-in in 8.899 Saltbr-in 2.9103 HRD-in -74.11, -46.73 62.28, 16.59 in-in-in SNCiii in-in ActLoopNT-in 2.9814 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -114.14, 157.89 APE9-dihe-na 63.24, 141.46 APE8-dihe-in -59.26, 134.49 APE8-rot-in 301.23 APE67-dihe-in -63.18, -25.69 -49.58, -43.74 APE12-dist-in 13.2265 APE11-dist-in 10.6332 APE10-dist-in 6.2445 APE9-dist-in 3.1592 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 29 29 0 [[13, 297]] 1.0 AF-O76039-K1 Homo sapiens CMGC_CDKL5_HUMAN CMGC 3e-85 292.0 1.0 300.0 300.0 152 153 154 156 158 42 60 64 132 134 133 135.0 193 181 176 175 174 173 172 171 170 90 Cyclin-dependent kinase-like 5
CMGC CDKL5 CDKL5_HUMAN AF-O76039-K3A O76039 5 305 960.0 No_ligand No_ligand Active DFGin 6.3799 14.5687 BLAminus -135.21, -179.4 59.2, 71.28 -81.53, 13.86 287.9, 78.93 -57.07, -40.59 in-in in 8.5058 Saltbr-in 2.7505 HRD-in -76.53, -47.61 66.44, 2.41 in-in-in SNCiii in-in ActLoopNT-in 2.9172 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.17, 153.4 APE9-dihe-na 60.48, 150.09 APE8-dihe-in -58.09, 134.7 APE8-rot-in 295.86 APE67-dihe-in -61.87, -22.51 -50.82, -39.79 APE12-dist-in 12.3194 APE11-dist-in 10.21 APE10-dist-in 6.0565 APE9-dist-in 3.7474 None None None AF2 -1.0 1.0 1.0 A 301.0 301.0 0 29 29 0 [[13, 297]] 1.0 AF-O76039-K3 Homo sapiens CMGC_CDKL5_HUMAN CMGC 3e-85 292.0 1.0 300.0 300.0 152 153 154 156 158 42 60 64 132 134 133 135.0 193 181 176 175 174 173 172 171 170 90 Cyclin-dependent kinase-like 5

PDB: AF-O76039 — CMGC CDKL5_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name