CDKL5 (Cyclin-dependent kinase-like 5)

Group: CMGC

Uniprot: CDKL5_HUMAN

Domain boundary: 13 - 297

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	4	AF-O76039-K1A

Database table as tsv

PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
AF-O76039-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	5 - 305	None	None	0
4BGQA	2.0	None	DFGin	BLAminus	out-out	in-none	38R	Type1	9 - 302	T169D,Y171E	None	11
8CIEA	2.2	Inactive	DFGin	BLAminus	in-in	in-out	US0	Type1	13 - 303	None	None	0
9EPUA	2.6	Inactive	DFGin	BLAminus	in-in	in-out	A1H6P	Type1	12 - 303	None	None	3

CDKL5 (Cyclin-dependent kinase-like 5)

Group: CMGC

Total number of chains: 4

Spatial	Dihedral	Chains	Representative
DFGin	BLAminus	4	AF-O76039-K1A

Database table as tsv

Organism	UniprotID	PDB	Resolution	Activity Label	Spatial Label	Dihedral Label	Chelix-SaltBridge	ActLoopNT-ActLoopCT	Ligand	Type	Residues in structure	Mutation	Phosphorylation	Unresolved residues in A-loop
Homo sapiens	CDKL5_HUMAN	AF-O76039-K1A	-1.0	Active	DFGin	BLAminus	in-in	in-in	No_ligand	No_ligand	5 - 305	None	None	0
Homo sapiens	CDKL5_HUMAN	4BGQA	2.0	None	DFGin	BLAminus	out-out	in-none	38R	Type1	9 - 302	T169D,Y171E	None	11
Homo sapiens	CDKL5_HUMAN	8CIEA	2.2	Inactive	DFGin	BLAminus	in-in	in-out	US0	Type1	13 - 303	None	None	0
Homo sapiens	CDKL5_HUMAN	9EPUA	2.6	Inactive	DFGin	BLAminus	in-in	in-out	A1H6P	Type1	12 - 303	None	None	3

CDKL5 (Cyclin-dependent kinase-like 5)

No non-human structures known.