PDB: AF-O75676 — AGC KS6A4_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-O75676-K1A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC RPS6KA4-1 KS6A4_HUMAN AF-O75676-K1A O75676 25 309 772.0 No_ligand No_ligand Active DFGin 6.598 13.71 BLAminus -124.98, -168.39 42.55, 70.55 -80.59, 14.7 297.97, 83.91 -61.19, -20.29 in-in in 8.77 Saltbr-in 2.604 HRD-in -82.76, -47.29 63.76, 4.18 in-in-in SNCiii in-in ActLoopNT-in 2.92 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.03, 161.17 APE9-dihe-na 111.84, 169.32 APE8-dihe-in -72.29, 131.49 APE8-rot-in 292.11 APE67-dihe-in -60.98, -29.84 -59.69, -36.55 APE12-dist-in 8.541 APE11-dist-in 11.517 APE10-dist-in 5.761 APE9-dist-in 3.594 None None None AF2 -1.0 1.0 1.0 A 285 285 0 0 0 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K1 AGC_RPS6KA4-1_HUMAN AGC 5.7e-92 313.4 1 260 260 178 179 180 182 184 65 85 89 158 160 159 161 220 207 202 201 200 199 198 197 196 116 Ribosomal protein S6 kinase alpha-4
AGC RPS6KA4-1 KS6A4_HUMAN AF-O75676-K3A O75676 25 309 772.0 No_ligand No_ligand Active DFGin 5.878 13.345 BLAminus -137.86, 174.13 57.75, 77.02 -80.17, 14.68 304.16, 99.37 -63.32, -16.55 in-in in 8.703 Saltbr-in 2.623 HRD-in -79.41, -52.95 68.65, 0.29 in-in-in SNCiii in-in ActLoopNT-in 2.884 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.69, 162.48 APE9-dihe-na 107.74, -177.94 APE8-dihe-in -90.07, 132.25 APE8-rot-in 304.86 APE67-dihe-in -59.91, -31.29 -62.41, -36.29 APE12-dist-in 8.34 APE11-dist-in 11.525 APE10-dist-in 5.775 APE9-dist-in 3.898 None None None AF2 -1.0 1.0 1.0 A 285 285 0 0 0 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K3 AGC_RPS6KA4-1_HUMAN AGC 5.7e-92 313.4 1 260 260 178 179 180 182 184 65 85 89 158 160 159 161 220 207 202 201 200 199 198 197 196 116 Ribosomal protein S6 kinase alpha-4
CAMK RPS6KA4-2 KS6A4_HUMAN AF-O75676-K2A O75676 400 682 772.0 No_ligand No_ligand Active DFGin 5.625 13.976 BLAminus -120.67, 178.37 58.42, 72.08 -82.57, 18.56 283.59, 66.24 -61.05, -28.33 in-in in 8.628 Saltbr-in 2.713 HRD-in -75.59, -46.6 67.67, -1.45 in-in-in SNCiii in-in ActLoopNT-in 2.803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.5, 118.13 APE9-dihe-na -165.28, 159.12 APE8-dihe-in -96.39, 123.29 APE8-rot-in 303.72 APE67-dihe-in -63.09, -21.71 -49.19, -44.65 APE12-dist-in 8.961 APE11-dist-in 10.83 APE10-dist-in 5.011 APE9-dist-in 4.145 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K2 CAMK_RPS6KA4-2_HUMAN CAMK 1.2e-79 273.2 5 256 252 550 551 552 554 556 440 453 457 527 529 528 530 591 579 574 573 572 571 570 569 568 484 Ribosomal protein S6 kinase alpha-4
CAMK RPS6KA4-2 KS6A4_HUMAN AF-O75676-K4A O75676 400 682 772.0 No_ligand No_ligand Active DFGin 5.176 14.02 BLAminus -122.38, 175.76 59.23, 72.02 -80.76, 17.2 284.29, 67.3 -58.65, -30.45 in-in in 8.538 Saltbr-in 2.684 HRD-in -77.81, -45.53 69.45, -2.15 in-in-in SNCiii in-in ActLoopNT-in 2.8 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.24, 117.86 APE9-dihe-na -166.45, 155.97 APE8-dihe-in -91.4, 121.79 APE8-rot-in 302.05 APE67-dihe-in -66.49, -20.11 -51.14, -42.05 APE12-dist-in 8.51 APE11-dist-in 11.128 APE10-dist-in 5.151 APE9-dist-in 4.202 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K4 CAMK_RPS6KA4-2_HUMAN CAMK 1.2e-79 273.2 5 256 252 550 551 552 554 556 440 453 457 527 529 528 530 591 579 574 573 572 571 570 569 568 484 Ribosomal protein S6 kinase alpha-4

PDB: AF-O75676 — AGC KS6A4_HUMAN

Total number of chains: 4
Active chains: 4
Total number of genes: 2
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% AF-O75676-K1A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
AGC RPS6KA4-1 KS6A4_HUMAN AF-O75676-K1A O75676 25 309 772.0 No_ligand No_ligand Active DFGin 6.598 13.71 BLAminus -124.98, -168.39 42.55, 70.55 -80.59, 14.7 297.97, 83.91 -61.19, -20.29 in-in in 8.77 Saltbr-in 2.604 HRD-in -82.76, -47.29 63.76, 4.18 in-in-in SNCiii in-in ActLoopNT-in 2.92 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -157.03, 161.17 APE9-dihe-na 111.84, 169.32 APE8-dihe-in -72.29, 131.49 APE8-rot-in 292.11 APE67-dihe-in -60.98, -29.84 -59.69, -36.55 APE12-dist-in 8.541 APE11-dist-in 11.517 APE10-dist-in 5.761 APE9-dist-in 3.594 None None None AF2 -1.0 1.0 1.0 A 285 285 0 0 0 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K1 Homo sapiens AGC_RPS6KA4-1_HUMAN AGC 5.7e-92 313.4 1 260 260 178 179 180 182 184 65 85 89 158 160 159 161 220 207 202 201 200 199 198 197 196 116 Ribosomal protein S6 kinase alpha-4
AGC RPS6KA4-1 KS6A4_HUMAN AF-O75676-K3A O75676 25 309 772.0 No_ligand No_ligand Active DFGin 5.878 13.345 BLAminus -137.86, 174.13 57.75, 77.02 -80.17, 14.68 304.16, 99.37 -63.32, -16.55 in-in in 8.703 Saltbr-in 2.623 HRD-in -79.41, -52.95 68.65, 0.29 in-in-in SNCiii in-in ActLoopNT-in 2.884 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -152.69, 162.48 APE9-dihe-na 107.74, -177.94 APE8-dihe-in -90.07, 132.25 APE8-rot-in 304.86 APE67-dihe-in -59.91, -31.29 -62.41, -36.29 APE12-dist-in 8.34 APE11-dist-in 11.525 APE10-dist-in 5.775 APE9-dist-in 3.898 None None None AF2 -1.0 1.0 1.0 A 285 285 0 0 0 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K3 Homo sapiens AGC_RPS6KA4-1_HUMAN AGC 5.7e-92 313.4 1 260 260 178 179 180 182 184 65 85 89 158 160 159 161 220 207 202 201 200 199 198 197 196 116 Ribosomal protein S6 kinase alpha-4
CAMK RPS6KA4-2 KS6A4_HUMAN AF-O75676-K2A O75676 400 682 772.0 No_ligand No_ligand Active DFGin 5.625 13.976 BLAminus -120.67, 178.37 58.42, 72.08 -82.57, 18.56 283.59, 66.24 -61.05, -28.33 in-in in 8.628 Saltbr-in 2.713 HRD-in -75.59, -46.6 67.67, -1.45 in-in-in SNCiii in-in ActLoopNT-in 2.803 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -141.5, 118.13 APE9-dihe-na -165.28, 159.12 APE8-dihe-in -96.39, 123.29 APE8-rot-in 303.72 APE67-dihe-in -63.09, -21.71 -49.19, -44.65 APE12-dist-in 8.961 APE11-dist-in 10.83 APE10-dist-in 5.011 APE9-dist-in 4.145 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K2 Homo sapiens CAMK_RPS6KA4-2_HUMAN CAMK 1.2e-79 273.2 5 256 252 550 551 552 554 556 440 453 457 527 529 528 530 591 579 574 573 572 571 570 569 568 484 Ribosomal protein S6 kinase alpha-4
CAMK RPS6KA4-2 KS6A4_HUMAN AF-O75676-K4A O75676 400 682 772.0 No_ligand No_ligand Active DFGin 5.176 14.02 BLAminus -122.38, 175.76 59.23, 72.02 -80.76, 17.2 284.29, 67.3 -58.65, -30.45 in-in in 8.538 Saltbr-in 2.684 HRD-in -77.81, -45.53 69.45, -2.15 in-in-in SNCiii in-in ActLoopNT-in 2.8 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.24, 117.86 APE9-dihe-na -166.45, 155.97 APE8-dihe-in -91.4, 121.79 APE8-rot-in 302.05 APE67-dihe-in -66.49, -20.11 -51.14, -42.05 APE12-dist-in 8.51 APE11-dist-in 11.128 APE10-dist-in 5.151 APE9-dist-in 4.202 None None None AF2 -1.0 1.0 1.0 A 283 283 0 0 0 0 [[33, 301], [408, 674]] 2.0 AF-O75676-K4 Homo sapiens CAMK_RPS6KA4-2_HUMAN CAMK 1.2e-79 273.2 5 256 252 550 551 552 554 556 440 453 457 527 529 528 530 591 579 574 573 572 571 570 569 568 484 Ribosomal protein S6 kinase alpha-4

PDB: AF-O75676 — AGC KS6A4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name