| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA5-1 | KS6A5_HUMAN | AF-O75582-K1A | O75582 | 41 | 326 | 802.0 | No_ligand | No_ligand | Active | DFGin | 6.7799 | 13.7903 | BLAminus | -122.36, -163.26 | 38.53, 66.9 | -78.09, 17.93 | 295.37, 82.19 | -64.85, -18.18 | in-in | in | 8.7965 | Saltbr-in | 2.6254 | HRD-in | -82.76, -49.06 | 64.23, 11.02 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8888 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -150.62, 163.8 | APE9-dihe-na | 113.59, 179.22 | APE8-dihe-in | -90.62, 126.59 | APE8-rot-in | 304.99 | APE67-dihe-in | -61.69, -29.36 | -58.71, -34.47 | APE12-dist-in | 8.4062 | APE11-dist-in | 11.5603 | APE10-dist-in | 5.8061 | APE9-dist-in | 3.5572 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 286.0 | 286.0 | 0 | 29 | 29 | 0 | [[49, 318], [423, 687]] | 2.0 | AF-O75582-K1 | AGC_RPS6KA5-1_HUMAN | AGC | 2e-93 | 318.2 | 1.0 | 260.0 | 260.0 | 194 | 195 | 196 | 198 | 200 | 81 | 101 | 105 | 174 | 176 | 175 | 177.0 | 237 | 223 | 218 | 217 | 216 | 215 | 214 | 213 | 212 | 132 | Ribosomal protein S6 kinase alpha-5 |
| AGC | RPS6KA5-1 | KS6A5_HUMAN | AF-O75582-K3A | O75582 | 41 | 326 | 802.0 | No_ligand | No_ligand | Active | DFGin | 6.1857 | 13.3584 | BLAminus | -132.07, -177.35 | 48.31, 79.01 | -81.08, 17.52 | 302.26, 93.07 | -63.99, -14.82 | in-in | in | 8.7021 | Saltbr-in | 2.5771 | HRD-in | -86.05, -53.15 | 68.0, 7.54 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9142 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -159.1, 160.71 | APE9-dihe-na | 110.46, -176.37 | APE8-dihe-in | -88.86, 131.0 | APE8-rot-in | 291.71 | APE67-dihe-in | -59.57, -30.36 | -60.19, -36.11 | APE12-dist-in | 8.1155 | APE11-dist-in | 11.4064 | APE10-dist-in | 5.697 | APE9-dist-in | 3.5899 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 286.0 | 286.0 | 0 | 29 | 29 | 0 | [[49, 318], [423, 687]] | 2.0 | AF-O75582-K3 | AGC_RPS6KA5-1_HUMAN | AGC | 2e-93 | 318.2 | 1.0 | 260.0 | 260.0 | 194 | 195 | 196 | 198 | 200 | 81 | 101 | 105 | 174 | 176 | 175 | 177.0 | 237 | 223 | 218 | 217 | 216 | 215 | 214 | 213 | 212 | 132 | Ribosomal protein S6 kinase alpha-5 |
| CAMK | RPS6KA5-2 | KS6A5_HUMAN | AF-O75582-K2A | O75582 | 415 | 695 | 802.0 | No_ligand | No_ligand | Active | DFGin | 5.6028 | 14.0382 | BLAminus | -121.39, 176.9 | 57.63, 77.29 | -87.03, 18.09 | 283.44, 63.26 | -60.04, -29.17 | in-in | in | 8.7342 | Saltbr-in | 2.7268 | HRD-in | -75.89, -46.83 | 67.59, -1.19 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8254 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -141.88, 121.73 | APE9-dihe-na | -165.89, 155.36 | APE8-dihe-in | -93.68, 121.29 | APE8-rot-in | 304.68 | APE67-dihe-in | -64.03, -19.39 | -46.88, -48.63 | APE12-dist-in | 8.8257 | APE11-dist-in | 11.0913 | APE10-dist-in | 5.3006 | APE9-dist-in | 4.395 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 281.0 | 281.0 | 0 | 28 | 28 | 0 | [[49, 318], [423, 687]] | 2.0 | AF-O75582-K2 | CAMK_RPS6KA5-2_HUMAN | CAMK | 1.2e-87 | 299.4 | 5.0 | 256.0 | 252.0 | 564 | 565 | 566 | 568 | 570 | 455 | 468 | 472 | 541 | 543 | 542 | 544.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 499 | Ribosomal protein S6 kinase alpha-5 |
| CAMK | RPS6KA5-2 | KS6A5_HUMAN | AF-O75582-K4A | O75582 | 415 | 695 | 802.0 | No_ligand | No_ligand | Active | DFGin | 5.317 | 14.018 | BLAminus | -120.15, 172.97 | 56.49, 82.73 | -88.05, 15.67 | 281.76, 63.73 | -57.32, -30.97 | in-in | in | 8.5347 | Saltbr-in | 2.6567 | HRD-in | -75.74, -48.78 | 70.38, -5.53 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8293 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.62, 115.33 | APE9-dihe-na | -171.98, 154.54 | APE8-dihe-in | -85.95, 120.48 | APE8-rot-in | 303.19 | APE67-dihe-in | -63.89, -23.3 | -49.53, -43.21 | APE12-dist-in | 8.7924 | APE11-dist-in | 11.4337 | APE10-dist-in | 5.7927 | APE9-dist-in | 4.0786 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 281.0 | 281.0 | 0 | 28 | 28 | 0 | [[49, 318], [423, 687]] | 2.0 | AF-O75582-K4 | CAMK_RPS6KA5-2_HUMAN | CAMK | 1.2e-87 | 299.4 | 5.0 | 256.0 | 252.0 | 564 | 565 | 566 | 568 | 570 | 455 | 468 | 472 | 541 | 543 | 542 | 544.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 499 | Ribosomal protein S6 kinase alpha-5 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | RPS6KA5-1 | KS6A5_HUMAN | AF-O75582-K1A | O75582 | 41 | 326 | 802.0 | No_ligand | No_ligand | Active | DFGin | 6.7799 | 13.7903 | BLAminus | -122.36, -163.26 | 38.53, 66.9 | -78.09, 17.93 | 295.37, 82.19 | -64.85, -18.18 | in-in | in | 8.7965 | Saltbr-in | 2.6254 | HRD-in | -82.76, -49.06 | 64.23, 11.02 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8888 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -150.62, 163.8 | APE9-dihe-na | 113.59, 179.22 | APE8-dihe-in | -90.62, 126.59 | APE8-rot-in | 304.99 | APE67-dihe-in | -61.69, -29.36 | -58.71, -34.47 | APE12-dist-in | 8.4062 | APE11-dist-in | 11.5603 | APE10-dist-in | 5.8061 | APE9-dist-in | 3.5572 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 286.0 | 286.0 | 0 | 29 | 29 | 0 | [[49, 318], [423, 687]] | 2.0 | AF-O75582-K1 | Homo sapiens | AGC_RPS6KA5-1_HUMAN | AGC | 2e-93 | 318.2 | 1.0 | 260.0 | 260.0 | 194 | 195 | 196 | 198 | 200 | 81 | 101 | 105 | 174 | 176 | 175 | 177.0 | 237 | 223 | 218 | 217 | 216 | 215 | 214 | 213 | 212 | 132 | Ribosomal protein S6 kinase alpha-5 |
| AGC | RPS6KA5-1 | KS6A5_HUMAN | AF-O75582-K3A | O75582 | 41 | 326 | 802.0 | No_ligand | No_ligand | Active | DFGin | 6.1857 | 13.3584 | BLAminus | -132.07, -177.35 | 48.31, 79.01 | -81.08, 17.52 | 302.26, 93.07 | -63.99, -14.82 | in-in | in | 8.7021 | Saltbr-in | 2.5771 | HRD-in | -86.05, -53.15 | 68.0, 7.54 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.9142 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -159.1, 160.71 | APE9-dihe-na | 110.46, -176.37 | APE8-dihe-in | -88.86, 131.0 | APE8-rot-in | 291.71 | APE67-dihe-in | -59.57, -30.36 | -60.19, -36.11 | APE12-dist-in | 8.1155 | APE11-dist-in | 11.4064 | APE10-dist-in | 5.697 | APE9-dist-in | 3.5899 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 286.0 | 286.0 | 0 | 29 | 29 | 0 | [[49, 318], [423, 687]] | 2.0 | AF-O75582-K3 | Homo sapiens | AGC_RPS6KA5-1_HUMAN | AGC | 2e-93 | 318.2 | 1.0 | 260.0 | 260.0 | 194 | 195 | 196 | 198 | 200 | 81 | 101 | 105 | 174 | 176 | 175 | 177.0 | 237 | 223 | 218 | 217 | 216 | 215 | 214 | 213 | 212 | 132 | Ribosomal protein S6 kinase alpha-5 |
| CAMK | RPS6KA5-2 | KS6A5_HUMAN | AF-O75582-K2A | O75582 | 415 | 695 | 802.0 | No_ligand | No_ligand | Active | DFGin | 5.6028 | 14.0382 | BLAminus | -121.39, 176.9 | 57.63, 77.29 | -87.03, 18.09 | 283.44, 63.26 | -60.04, -29.17 | in-in | in | 8.7342 | Saltbr-in | 2.7268 | HRD-in | -75.89, -46.83 | 67.59, -1.19 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8254 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -141.88, 121.73 | APE9-dihe-na | -165.89, 155.36 | APE8-dihe-in | -93.68, 121.29 | APE8-rot-in | 304.68 | APE67-dihe-in | -64.03, -19.39 | -46.88, -48.63 | APE12-dist-in | 8.8257 | APE11-dist-in | 11.0913 | APE10-dist-in | 5.3006 | APE9-dist-in | 4.395 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 281.0 | 281.0 | 0 | 28 | 28 | 0 | [[49, 318], [423, 687]] | 2.0 | AF-O75582-K2 | Homo sapiens | CAMK_RPS6KA5-2_HUMAN | CAMK | 1.2e-87 | 299.4 | 5.0 | 256.0 | 252.0 | 564 | 565 | 566 | 568 | 570 | 455 | 468 | 472 | 541 | 543 | 542 | 544.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 499 | Ribosomal protein S6 kinase alpha-5 |
| CAMK | RPS6KA5-2 | KS6A5_HUMAN | AF-O75582-K4A | O75582 | 415 | 695 | 802.0 | No_ligand | No_ligand | Active | DFGin | 5.317 | 14.018 | BLAminus | -120.15, 172.97 | 56.49, 82.73 | -88.05, 15.67 | 281.76, 63.73 | -57.32, -30.97 | in-in | in | 8.5347 | Saltbr-in | 2.6567 | HRD-in | -75.74, -48.78 | 70.38, -5.53 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.8293 | ActLoopCT-in | nonTYR | APEdihe_aaiii | APEdist_iiii | APE10-dihe-na | -155.62, 115.33 | APE9-dihe-na | -171.98, 154.54 | APE8-dihe-in | -85.95, 120.48 | APE8-rot-in | 303.19 | APE67-dihe-in | -63.89, -23.3 | -49.53, -43.21 | APE12-dist-in | 8.7924 | APE11-dist-in | 11.4337 | APE10-dist-in | 5.7927 | APE9-dist-in | 4.0786 | None | None | None | AF2 | -1.0 | 1.0 | 1.0 | A | 281.0 | 281.0 | 0 | 28 | 28 | 0 | [[49, 318], [423, 687]] | 2.0 | AF-O75582-K4 | Homo sapiens | CAMK_RPS6KA5-2_HUMAN | CAMK | 1.2e-87 | 299.4 | 5.0 | 256.0 | 252.0 | 564 | 565 | 566 | 568 | 570 | 455 | 468 | 472 | 541 | 543 | 542 | 544.0 | 604 | 592 | 587 | 586 | 585 | 584 | 583 | 582 | 581 | 499 | Ribosomal protein S6 kinase alpha-5 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|