PDB: 9MC0 — CMGC DYRK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 9MC0A
DFGin BLAminus 1 50.0% 9MC0B
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK2 DYRK2_HUMAN 9MC0A Q92630 151 537 601.0 A1ENX:60501 Type1 Inactive DFGin 7.01 15.659 ABAminus DFGAsp-rot-in -121.5295, -28.2053 -101.968, 91.4483 189.1326, 5.363 -100.9836, 12.9429 283.5743, 81.7206 -64.8514, -18.2406 in-in in 9.263 Saltbr-in 2.68 HRD-out -87.484, 96.5983 -83.9819, 14.3292 in-in-out SNCiio in-out ActLoopNT-in 2.773 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.6242, 172.3027 APE9-dihe-na 71.7169, 144.0626 APE8-dihe-in -66.2699, 144.2892 APE8-rot-out 181.6621 APE67-dihe-in -61.1874, -30.7674 -57.1534, -44.69 APE12-dist-in 13.167 APE11-dist-in 11.973 APE10-dist-in 7.479 APE9-dist-in 3.151 None PTR382 PTR382 XRAY 2.87 0.248 0.292 A 387 387 0 0 0 0 [[222, 535]] 1.0 9mc0 CMGC_DYRK2_HUMAN CMGC 1.1e-98 336.2 1 301 301 367 368 369 371 373 251 266 270 345 347 346 348 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2
CMGC DYRK2 DYRK2_HUMAN 9MC0B Q92630 151 537 601.0 A1ENX:60501 Type1 Inactive DFGin 7.086 15.338 BLAminus DFGAsp-rot-in -127.44, -178.2103 57.5695, 63.8622 205.0689, 7.3503 -86.5641, 21.5244 286.8598, 80.3443 -62.5025, -41.2359 in-in in 9.25 Saltbr-in 2.701 HRD-in -62.0411, -44.7799 74.9841, -8.0938 in-in-out SNCiio in-out ActLoopNT-in 2.764 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -124.5463, 168.7583 APE9-dihe-na 71.8794, 143.187 APE8-dihe-in -63.3349, 146.996 APE8-rot-out 182.6613 APE67-dihe-in -62.3845, -43.0761 -60.3932, -40.2349 APE12-dist-in 12.729 APE11-dist-in 11.436 APE10-dist-in 7.06 APE9-dist-in 3.206 None PTR382 PTR382 XRAY 2.87 0.248 0.292 B 387 387 0 0 0 0 [[222, 535]] 1.0 9mc0 CMGC_DYRK2_HUMAN CMGC 1.1e-98 336.2 1 301 301 367 368 369 371 373 251 266 270 345 347 346 348 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2

PDB: 9MC0 — CMGC DYRK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 1 50.0% 9MC0A
DFGin BLAminus 1 50.0% 9MC0B
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC DYRK2 DYRK2_HUMAN 9MC0A Q92630 151 537 601.0 A1ENX:60501 Type1 Inactive DFGin 7.01 15.659 ABAminus DFGAsp-rot-in -121.5295, -28.2053 -101.968, 91.4483 189.1326, 5.363 -100.9836, 12.9429 283.5743, 81.7206 -64.8514, -18.2406 in-in in 9.263 Saltbr-in 2.68 HRD-out -87.484, 96.5983 -83.9819, 14.3292 in-in-out SNCiio in-out ActLoopNT-in 2.773 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -132.6242, 172.3027 APE9-dihe-na 71.7169, 144.0626 APE8-dihe-in -66.2699, 144.2892 APE8-rot-out 181.6621 APE67-dihe-in -61.1874, -30.7674 -57.1534, -44.69 APE12-dist-in 13.167 APE11-dist-in 11.973 APE10-dist-in 7.479 APE9-dist-in 3.151 None PTR382 PTR382 XRAY 2.87 0.248 0.292 A 387 387 0 0 0 0 [[222, 535]] 1.0 9mc0 Homo sapiens CMGC_DYRK2_HUMAN CMGC 1.1e-98 336.2 1 301 301 367 368 369 371 373 251 266 270 345 347 346 348 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2
CMGC DYRK2 DYRK2_HUMAN 9MC0B Q92630 151 537 601.0 A1ENX:60501 Type1 Inactive DFGin 7.086 15.338 BLAminus DFGAsp-rot-in -127.44, -178.2103 57.5695, 63.8622 205.0689, 7.3503 -86.5641, 21.5244 286.8598, 80.3443 -62.5025, -41.2359 in-in in 9.25 Saltbr-in 2.701 HRD-in -62.0411, -44.7799 74.9841, -8.0938 in-in-out SNCiio in-out ActLoopNT-in 2.764 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -124.5463, 168.7583 APE9-dihe-na 71.8794, 143.187 APE8-dihe-in -63.3349, 146.996 APE8-rot-out 182.6613 APE67-dihe-in -62.3845, -43.0761 -60.3932, -40.2349 APE12-dist-in 12.729 APE11-dist-in 11.436 APE10-dist-in 7.06 APE9-dist-in 3.206 None PTR382 PTR382 XRAY 2.87 0.248 0.292 B 387 387 0 0 0 0 [[222, 535]] 1.0 9mc0 Homo sapiens CMGC_DYRK2_HUMAN CMGC 1.1e-98 336.2 1 301 301 367 368 369 371 373 251 266 270 345 347 346 348 404 392 387 386 385 384 383 382 381 302 Dual specificity tyrosine-phosphorylation-regulated kinase 2

PDB: 9MC0 — CMGC DYRK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label DFG-Asp_rot_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Asp
χ1,χ2		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name