PDB: 9JK1 — CMGC CDK12_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9JK1B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK12 CDK12_HUMAN 9JK1A Q9NYV4 717 1039 1490.0 A1EB3:1202 Type1 Inactive DFGin 7.136 16.1944 BLAminus -133.53, 173.61 54.27, 71.41 -88.96, 16.92 270.96, 77.73 -63.15, -30.31 in-in in 8.4971 Saltbr-in 3.2847 HRD-in -81.17, -44.88 64.66, 14.44 in-in-out SNCiio in-out ActLoopNT-in 2.8569 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.0, -26.54 APE9-dihe-na -103.25, 143.89 APE8-dihe-in -52.76, 144.9 APE8-rot-out 169.48 APE67-dihe-in -66.06, -18.64 -58.71, -34.25 APE12-dist-in 13.7501 APE11-dist-in 12.2647 APE10-dist-in 7.1765 APE9-dist-in 3.888 None TPO893 TPO893 XRAY 2.72 0.249 0.267 A 340.0 311.0 12 29 27 2 [[727, 1020]] 1.0 9jk1 CMGC_CDK12_HUMAN CMGC 2.6e-84 289.0 1.0 301.0 301.0 876 877 878 880 882 756 774 778 856 858 857 859.0 918 905 900 899 898 897 896 895 894 814 Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 9JK1B Q9NYV4 715 1039 1490.0 A1EB3:1101 Type1 Inactive DFGin 6.9737 15.7959 BLAminus -131.76, 174.62 55.08, 70.72 -88.19, 16.31 271.01, 79.18 -62.74, -29.13 in-in in 8.5172 Saltbr-in 3.0362 HRD-in -81.5, -44.39 65.05, 13.56 in-in-out SNCiio in-out ActLoopNT-in 3.1501 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.88, -41.9 APE9-dihe-na -106.09, 143.29 APE8-dihe-in -52.94, 146.84 APE8-rot-out 167.82 APE67-dihe-in -65.97, -16.6 -59.29, -37.44 APE12-dist-in 13.6164 APE11-dist-in 11.5844 APE10-dist-in 7.2432 APE9-dist-in 3.6611 None TPO893 TPO893 XRAY 2.72 0.249 0.267 B 340.0 315.0 10 29 29 0 [[727, 1020]] 1.0 9jk1 CMGC_CDK12_HUMAN CMGC 2.6e-84 289.0 1.0 301.0 301.0 876 877 878 880 882 756 774 778 856 858 857 859.0 918 905 900 899 898 897 896 895 894 814 Cyclin-dependent kinase 12

PDB: 9JK1 — CMGC CDK12_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 9JK1B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CMGC CDK12 CDK12_HUMAN 9JK1A Q9NYV4 717 1039 1490.0 A1EB3:1202 Type1 Inactive DFGin 7.136 16.1944 BLAminus -133.53, 173.61 54.27, 71.41 -88.96, 16.92 270.96, 77.73 -63.15, -30.31 in-in in 8.4971 Saltbr-in 3.2847 HRD-in -81.17, -44.88 64.66, 14.44 in-in-out SNCiio in-out ActLoopNT-in 2.8569 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -131.0, -26.54 APE9-dihe-na -103.25, 143.89 APE8-dihe-in -52.76, 144.9 APE8-rot-out 169.48 APE67-dihe-in -66.06, -18.64 -58.71, -34.25 APE12-dist-in 13.7501 APE11-dist-in 12.2647 APE10-dist-in 7.1765 APE9-dist-in 3.888 None TPO893 TPO893 XRAY 2.72 0.249 0.267 A 340.0 311.0 12 29 27 2 [[727, 1020]] 1.0 9jk1 Homo sapiens CMGC_CDK12_HUMAN CMGC 2.6e-84 289.0 1.0 301.0 301.0 876 877 878 880 882 756 774 778 856 858 857 859.0 918 905 900 899 898 897 896 895 894 814 Cyclin-dependent kinase 12
CMGC CDK12 CDK12_HUMAN 9JK1B Q9NYV4 715 1039 1490.0 A1EB3:1101 Type1 Inactive DFGin 6.9737 15.7959 BLAminus -131.76, 174.62 55.08, 70.72 -88.19, 16.31 271.01, 79.18 -62.74, -29.13 in-in in 8.5172 Saltbr-in 3.0362 HRD-in -81.5, -44.39 65.05, 13.56 in-in-out SNCiio in-out ActLoopNT-in 3.1501 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -130.88, -41.9 APE9-dihe-na -106.09, 143.29 APE8-dihe-in -52.94, 146.84 APE8-rot-out 167.82 APE67-dihe-in -65.97, -16.6 -59.29, -37.44 APE12-dist-in 13.6164 APE11-dist-in 11.5844 APE10-dist-in 7.2432 APE9-dist-in 3.6611 None TPO893 TPO893 XRAY 2.72 0.249 0.267 B 340.0 315.0 10 29 29 0 [[727, 1020]] 1.0 9jk1 Homo sapiens CMGC_CDK12_HUMAN CMGC 2.6e-84 289.0 1.0 301.0 301.0 876 877 878 880 882 756 774 778 856 858 857 859.0 918 905 900 899 898 897 896 895 894 814 Cyclin-dependent kinase 12

PDB: 9JK1 — CMGC CDK12_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name