| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | BTK | BTK_MOUSE | 9EJRA | P35991 | 394 | 659 | 659.0 | A1BI0:701 | Type1.5_Front | Inactive | DFGin | 5.9148 | 13.6438 | BLBplus | -146.74, 166.14 | 62.28, 23.66 | -68.17, 124.47 | 38.27, 88.12 | 78.54, 14.19 | out-out | out | 15.6993 | Saltbr-out | 15.7409 | HRD-in | -72.31, -57.13 | 80.67, 0.3 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.8158 | ActLoopCT-out | TYR | APEdihe_iooai | APEdist_aaao | APE10-dihe-in | -92.94, 175.88 | APE9-dihe-out | -65.52, -38.77 | APE8-dihe-out | -63.32, -1.31 | APE8-rot-na | 335.74 | APE67-dihe-in | -69.18, -9.94 | -59.0, -31.83 | APE12-dist-na | 21.4888 | APE11-dist-na | 20.0612 | APE10-dist-na | 15.1372 | APE9-dist-out | 11.1199 | L390G,Y551E,Y617P | None | None | XRAY | 2.1 | 0.25 | 0.295 | A | 279.0 | 260.0 | 6 | 29 | 23 | 6 | [[402, 653]] | 1.0 | 9ejr | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| TYR | BTK | BTK_MOUSE | 9EJRB | P35991 | 394 | 659 | 659.0 | A1BI0:701 | Type1.5_Front | Inactive | DFGin | 5.5791 | 14.023 | BLBplus | -146.82, 168.57 | 65.02, 26.83 | -69.27, 132.22 | 36.8, 90.68 | 70.75, 10.33 | out-out | out | 16.1259 | Saltbr-out | 17.3767 | HRD-in | -76.4, -57.97 | 82.93, -6.46 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.8983 | ActLoopCT-out | TYR | APEdihe_iooai | APEdist_aaao | APE10-dihe-in | -73.95, 158.19 | APE9-dihe-out | -60.45, -36.51 | APE8-dihe-out | -63.06, -4.13 | APE8-rot-na | 335.95 | APE67-dihe-in | -67.11, -17.18 | -54.59, -31.21 | APE12-dist-na | 999.0 | APE11-dist-na | 19.985 | APE10-dist-na | 13.9759 | APE9-dist-out | 10.8815 | L390G,Y551E,Y617P | None | None | XRAY | 2.1 | 0.25 | 0.295 | B | 279.0 | 256.0 | 10 | 29 | 21 | 8 | [[402, 653]] | 1.0 | 9ejr | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | BTK | BTK_MOUSE | 9EJRA | P35991 | 394 | 659 | 659.0 | A1BI0:701 | Type1.5_Front | Inactive | DFGin | 5.9148 | 13.6438 | BLBplus | -146.74, 166.14 | 62.28, 23.66 | -68.17, 124.47 | 38.27, 88.12 | 78.54, 14.19 | out-out | out | 15.6993 | Saltbr-out | 15.7409 | HRD-in | -72.31, -57.13 | 80.67, 0.3 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.8158 | ActLoopCT-out | TYR | APEdihe_iooai | APEdist_aaao | APE10-dihe-in | -92.94, 175.88 | APE9-dihe-out | -65.52, -38.77 | APE8-dihe-out | -63.32, -1.31 | APE8-rot-na | 335.74 | APE67-dihe-in | -69.18, -9.94 | -59.0, -31.83 | APE12-dist-na | 21.4888 | APE11-dist-na | 20.0612 | APE10-dist-na | 15.1372 | APE9-dist-out | 11.1199 | L390G,Y551E,Y617P | None | None | XRAY | 2.1 | 0.25 | 0.295 | A | 279.0 | 260.0 | 6 | 29 | 23 | 6 | [[402, 653]] | 1.0 | 9ejr | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| TYR | BTK | BTK_MOUSE | 9EJRB | P35991 | 394 | 659 | 659.0 | A1BI0:701 | Type1.5_Front | Inactive | DFGin | 5.5791 | 14.023 | BLBplus | -146.82, 168.57 | 65.02, 26.83 | -69.27, 132.22 | 36.8, 90.68 | 70.75, 10.33 | out-out | out | 16.1259 | Saltbr-out | 17.3767 | HRD-in | -76.4, -57.97 | 82.93, -6.46 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.8983 | ActLoopCT-out | TYR | APEdihe_iooai | APEdist_aaao | APE10-dihe-in | -73.95, 158.19 | APE9-dihe-out | -60.45, -36.51 | APE8-dihe-out | -63.06, -4.13 | APE8-rot-na | 335.95 | APE67-dihe-in | -67.11, -17.18 | -54.59, -31.21 | APE12-dist-na | 999.0 | APE11-dist-na | 19.985 | APE10-dist-na | 13.9759 | APE9-dist-out | 10.8815 | L390G,Y551E,Y617P | None | None | XRAY | 2.1 | 0.25 | 0.295 | B | 279.0 | 256.0 | 10 | 29 | 21 | 8 | [[402, 653]] | 1.0 | 9ejr | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |