| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | BTK | BTK_MOUSE | 9EJJA | P35991 | 394 | 659 | 659.0 | A1BIZ:701 | Type1.5_Front | Inactive | DFGin | 5.7614 | 13.6487 | BLBplus | -147.32, 173.09 | 58.85, 28.19 | -76.07, 130.26 | 40.28, 86.74 | 72.63, 22.79 | out-out | out | 15.3914 | Saltbr-out | 16.7212 | HRD-in | -81.76, -55.09 | 79.59, -6.11 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.8703 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | -88.9, -177.8 | APE9-dihe-out | -69.14, -44.42 | APE8-dihe-out | -58.97, -6.69 | APE8-rot-na | 334.43 | APE67-dihe-in | -64.23, -15.53 | -59.83, -30.31 | APE12-dist-na | 999.0 | APE11-dist-na | 19.696 | APE10-dist-na | 15.0024 | APE9-dist-out | 11.0263 | L390G,Y551E,Y617P | None | None | XRAY | 2.03 | 0.225 | 0.242 | A | 279.0 | 258.0 | 8 | 29 | 22 | 7 | [[402, 653]] | 1.0 | 9ejj | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| TYR | BTK | BTK_MOUSE | 9EJJB | P35991 | 394 | 659 | 659.0 | A1BIZ:701 | Type1.5_Front | Inactive | DFGin | 5.5008 | 14.0729 | BLBplus | -153.48, 175.7 | 63.93, 27.52 | -79.9, 134.25 | 41.75, 85.89 | 73.22, 13.03 | out-out | out | 16.4746 | Saltbr-out | 15.5152 | HRD-in | -79.13, -52.93 | 77.61, -0.8 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.9037 | ActLoopCT-out | TYR | APEdihe_iooai | APEdist_aaao | APE10-dihe-in | -93.15, 172.37 | APE9-dihe-out | -61.71, -38.19 | APE8-dihe-out | -62.73, -3.38 | APE8-rot-na | 336.57 | APE67-dihe-in | -68.39, -9.76 | -59.68, -31.05 | APE12-dist-na | 999.0 | APE11-dist-na | 19.4777 | APE10-dist-na | 14.5039 | APE9-dist-out | 10.8675 | L390G,Y551E,Y617P | None | None | XRAY | 2.03 | 0.225 | 0.242 | B | 279.0 | 256.0 | 10 | 29 | 21 | 8 | [[402, 653]] | 1.0 | 9ejj | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | BTK | BTK_MOUSE | 9EJJA | P35991 | 394 | 659 | 659.0 | A1BIZ:701 | Type1.5_Front | Inactive | DFGin | 5.7614 | 13.6487 | BLBplus | -147.32, 173.09 | 58.85, 28.19 | -76.07, 130.26 | 40.28, 86.74 | 72.63, 22.79 | out-out | out | 15.3914 | Saltbr-out | 16.7212 | HRD-in | -81.76, -55.09 | 79.59, -6.11 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.8703 | ActLoopCT-out | TYR | APEdihe_oooai | APEdist_aaao | APE10-dihe-out | -88.9, -177.8 | APE9-dihe-out | -69.14, -44.42 | APE8-dihe-out | -58.97, -6.69 | APE8-rot-na | 334.43 | APE67-dihe-in | -64.23, -15.53 | -59.83, -30.31 | APE12-dist-na | 999.0 | APE11-dist-na | 19.696 | APE10-dist-na | 15.0024 | APE9-dist-out | 11.0263 | L390G,Y551E,Y617P | None | None | XRAY | 2.03 | 0.225 | 0.242 | A | 279.0 | 258.0 | 8 | 29 | 22 | 7 | [[402, 653]] | 1.0 | 9ejj | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |
| TYR | BTK | BTK_MOUSE | 9EJJB | P35991 | 394 | 659 | 659.0 | A1BIZ:701 | Type1.5_Front | Inactive | DFGin | 5.5008 | 14.0729 | BLBplus | -153.48, 175.7 | 63.93, 27.52 | -79.9, 134.25 | 41.75, 85.89 | 73.22, 13.03 | out-out | out | 16.4746 | Saltbr-out | 15.5152 | HRD-in | -79.13, -52.93 | 77.61, -0.8 | out-out-out | SNCooo | out-out | ActLoopNT-out | 7.9037 | ActLoopCT-out | TYR | APEdihe_iooai | APEdist_aaao | APE10-dihe-in | -93.15, 172.37 | APE9-dihe-out | -61.71, -38.19 | APE8-dihe-out | -62.73, -3.38 | APE8-rot-na | 336.57 | APE67-dihe-in | -68.39, -9.76 | -59.68, -31.05 | APE12-dist-na | 999.0 | APE11-dist-na | 19.4777 | APE10-dist-na | 14.5039 | APE9-dist-out | 10.8675 | L390G,Y551E,Y617P | None | None | XRAY | 2.03 | 0.225 | 0.242 | B | 279.0 | 256.0 | 10 | 29 | 21 | 8 | [[402, 653]] | 1.0 | 9ejj | Mus musculus | TYR_BTK_MOUSE | TYR | 1.3e-92 | 315.7 | 1.0 | 258.0 | 258.0 | 538 | 539 | 540 | 542 | 544 | 430 | 445 | 449 | 518 | 520 | 519 | 521.0 | 579 | 567 | 562 | 561 | 560 | 559 | 558 | 557 | 556 | 475 | Tyrosine-protein kinase BTK |