PDB: 8W38 — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8W38A
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 8W38A P21802 467 764 821.0 TZ0:801 Type1.5_Back Inactive DFGin 5.884 13.939 BLAminus -141.73, -172.44 58.43, 85.09 -99.65, 33.03 296.5, 153.04 -60.44, -42.96 in-in in 7.716 Saltbr-in 2.73 HRD-in -67.46, -57.27 77.66, 6.76 in-in-out SNCiio in-out ActLoopNT-in 2.853 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -102.69, 6.19 APE9-dihe-in -92.48, 138.52 APE8-dihe-in -67.31, 130.89 APE8-rot-na 342.55 APE67-dihe-in -76.49, 2.73 -63.26, -44.89 APE12-dist-na 9.938 APE11-dist-na 10.863 APE10-dist-na 7.187 APE9-dist-in 4.84 N549D,D650V None None XRAY 2.6 0.337 0.359 A 324 298 0 0 0 0 [[481, 759]] 1.0 8w38 TYR_FGFR2_HUMAN TYR 1.5e-103 351.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38B P21802 467 764 821.0 TZ0:801 Type1.5_Back Inactive DFGin 5.917 13.867 BLAminus -141.61, -172.11 58.71, 84.88 -99.53, 33.01 296.86, 151.72 -60.67, -42.8 in-in in 7.677 Saltbr-in 2.736 HRD-in -66.89, -57.79 77.67, 7.38 in-in-out SNCiio in-out ActLoopNT-in 2.854 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -102.73, 7.76 APE9-dihe-in -92.14, 138.79 APE8-dihe-in -66.97, 130.73 APE8-rot-na 341.51 APE67-dihe-in -76.67, 2.98 -63.37, -44.91 APE12-dist-na 9.766 APE11-dist-na 10.751 APE10-dist-na 7.194 APE9-dist-in 4.826 N549D,D650V None None XRAY 2.6 0.337 0.359 B 324 288 10 0 0 6 [[481, 759]] 1.0 8w38 TYR_FGFR2_HUMAN TYR 1.5e-103 351.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38C P21802 465 764 821.0 TZ0:801 Type1.5_Back Inactive DFGin 5.905 14.001 BLAminus -141.73, -172.23 58.36, 85.55 -99.69, 32.51 297.47, 150.87 -60.14, -43.03 in-in in 7.766 Saltbr-in 2.733 HRD-in -67.3, -57.38 78.5, 5.79 in-in-out SNCiio in-out ActLoopNT-in 2.853 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.74, 8.72 APE9-dihe-in -90.56, 139.47 APE8-dihe-in -66.09, 130.7 APE8-rot-na 342.51 APE67-dihe-in -75.82, 2.85 -65.85, -41.6 APE12-dist-na 999.0 APE11-dist-na 10.65 APE10-dist-na 7.238 APE9-dist-in 4.776 N549D,D650V None None XRAY 2.6 0.337 0.359 C 324 289 11 0 0 11 [[481, 759]] 1.0 8w38 TYR_FGFR2_HUMAN TYR 1.5e-103 351.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38D P21802 467 764 821.0 TZ0:800 Type1.5_Back Inactive DFGin 5.958 13.994 BLAminus -141.63, -172.13 58.59, 85.21 -99.57, 33.16 297.38, 150.22 -60.22, -43.6 in-in in 7.782 Saltbr-in 2.764 HRD-in -66.88, -57.89 78.41, 5.63 in-in-out SNCiio in-out ActLoopNT-in 2.851 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.9, 7.03 APE9-dihe-in -91.06, 139.7 APE8-dihe-in -66.27, 130.75 APE8-rot-na 343.36 APE67-dihe-in -75.84, 2.91 -65.4, -41.85 APE12-dist-na 999.0 APE11-dist-na 10.75 APE10-dist-na 7.22 APE9-dist-in 4.794 N549D,D650V None None XRAY 2.6 0.337 0.359 D 324 271 27 0 0 11 [[481, 759]] 1.0 8w38 TYR_FGFR2_HUMAN TYR 1.5e-103 351.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 8W38 — TYR FGFR2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8W38A
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR FGFR2 FGFR2_HUMAN 8W38A P21802 467 764 821.0 TZ0:801 Type1.5_Back Inactive DFGin 5.884 13.939 BLAminus -141.73, -172.44 58.43, 85.09 -99.65, 33.03 296.5, 153.04 -60.44, -42.96 in-in in 7.716 Saltbr-in 2.73 HRD-in -67.46, -57.27 77.66, 6.76 in-in-out SNCiio in-out ActLoopNT-in 2.853 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -102.69, 6.19 APE9-dihe-in -92.48, 138.52 APE8-dihe-in -67.31, 130.89 APE8-rot-na 342.55 APE67-dihe-in -76.49, 2.73 -63.26, -44.89 APE12-dist-na 9.938 APE11-dist-na 10.863 APE10-dist-na 7.187 APE9-dist-in 4.84 N549D,D650V None None XRAY 2.6 0.337 0.359 A 324 298 0 0 0 0 [[481, 759]] 1.0 8w38 Homo sapiens TYR_FGFR2_HUMAN TYR 1.5e-103 351.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38B P21802 467 764 821.0 TZ0:801 Type1.5_Back Inactive DFGin 5.917 13.867 BLAminus -141.61, -172.11 58.71, 84.88 -99.53, 33.01 296.86, 151.72 -60.67, -42.8 in-in in 7.677 Saltbr-in 2.736 HRD-in -66.89, -57.79 77.67, 7.38 in-in-out SNCiio in-out ActLoopNT-in 2.854 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -102.73, 7.76 APE9-dihe-in -92.14, 138.79 APE8-dihe-in -66.97, 130.73 APE8-rot-na 341.51 APE67-dihe-in -76.67, 2.98 -63.37, -44.91 APE12-dist-na 9.766 APE11-dist-na 10.751 APE10-dist-na 7.194 APE9-dist-in 4.826 N549D,D650V None None XRAY 2.6 0.337 0.359 B 324 288 10 0 0 6 [[481, 759]] 1.0 8w38 Homo sapiens TYR_FGFR2_HUMAN TYR 1.5e-103 351.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38C P21802 465 764 821.0 TZ0:801 Type1.5_Back Inactive DFGin 5.905 14.001 BLAminus -141.73, -172.23 58.36, 85.55 -99.69, 32.51 297.47, 150.87 -60.14, -43.03 in-in in 7.766 Saltbr-in 2.733 HRD-in -67.3, -57.38 78.5, 5.79 in-in-out SNCiio in-out ActLoopNT-in 2.853 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.74, 8.72 APE9-dihe-in -90.56, 139.47 APE8-dihe-in -66.09, 130.7 APE8-rot-na 342.51 APE67-dihe-in -75.82, 2.85 -65.85, -41.6 APE12-dist-na 999.0 APE11-dist-na 10.65 APE10-dist-na 7.238 APE9-dist-in 4.776 N549D,D650V None None XRAY 2.6 0.337 0.359 C 324 289 11 0 0 11 [[481, 759]] 1.0 8w38 Homo sapiens TYR_FGFR2_HUMAN TYR 1.5e-103 351.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2
TYR FGFR2 FGFR2_HUMAN 8W38D P21802 467 764 821.0 TZ0:800 Type1.5_Back Inactive DFGin 5.958 13.994 BLAminus -141.63, -172.13 58.59, 85.21 -99.57, 33.16 297.38, 150.22 -60.22, -43.6 in-in in 7.782 Saltbr-in 2.764 HRD-in -66.88, -57.89 78.41, 5.63 in-in-out SNCiio in-out ActLoopNT-in 2.851 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -100.9, 7.03 APE9-dihe-in -91.06, 139.7 APE8-dihe-in -66.27, 130.75 APE8-rot-na 343.36 APE67-dihe-in -75.84, 2.91 -65.4, -41.85 APE12-dist-na 999.0 APE11-dist-na 10.75 APE10-dist-na 7.22 APE9-dist-in 4.794 N549D,D650V None None XRAY 2.6 0.337 0.359 D 324 271 27 0 0 11 [[481, 759]] 1.0 8w38 Homo sapiens TYR_FGFR2_HUMAN TYR 1.5e-103 351.6 1 260 260 643 644 645 647 649 517 534 538 623 625 624 626 685 673 668 667 666 665 664 663 662 565 Fibroblast growth factor receptor 2

PDB: 8W38 — TYR FGFR2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name