| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | MARK3 | MARK3_HUMAN | 8UOJA | P27448 | 50 | 370 | 753.0 | X5I:401,BEZ:408 | Type1,Allosteric | Inactive | DFGin | 10.5796 | 18.0713 | BLBtrans | -101.05, 155.21 | 67.06, 21.18 | -66.94, 120.95 | 226.3, 128.46 | 101.28, -16.49 | out-out | out | 11.0581 | Saltbr-out | 8.2805 | HRD-in | -69.51, -52.67 | 78.76, -9.16 | out-out-out | SNCooo | out-out | ActLoopNT-out | 9.6283 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_oooi | APE10-dihe-na | 71.66, 19.37 | APE9-dihe-na | -168.75, -176.01 | APE8-dihe-in | -87.16, 114.56 | APE8-rot-out | 184.74 | APE67-dihe-in | -62.01, -17.38 | -58.58, -38.0 | APE12-dist-out | 17.3988 | APE11-dist-out | 15.69 | APE10-dist-out | 10.5158 | APE9-dist-in | 5.6024 | I62L,L72R,V116I,G137K,F141Y,A146E | None | CME213 | XRAY | 1.6 | 0.16 | 0.186 | A | 328.0 | 321.0 | 0 | 27 | 27 | 0 | [[56, 307]] | 1.0 | 8uoj | CAMK_MARK3_HUMAN | CAMK | 5.9e-96 | 326.7 | 1.0 | 256.0 | 256.0 | 195 | 196 | 197 | 199 | 201 | 85 | 103 | 107 | 175 | 177 | 176 | 178.0 | 235 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 133 | MAP/microtubule affinity-regulating kinase 3 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK | MARK3 | MARK3_HUMAN | 8UOJA | P27448 | 50 | 370 | 753.0 | X5I:401,BEZ:408 | Type1,Allosteric | Inactive | DFGin | 10.5796 | 18.0713 | BLBtrans | -101.05, 155.21 | 67.06, 21.18 | -66.94, 120.95 | 226.3, 128.46 | 101.28, -16.49 | out-out | out | 11.0581 | Saltbr-out | 8.2805 | HRD-in | -69.51, -52.67 | 78.76, -9.16 | out-out-out | SNCooo | out-out | ActLoopNT-out | 9.6283 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_oooi | APE10-dihe-na | 71.66, 19.37 | APE9-dihe-na | -168.75, -176.01 | APE8-dihe-in | -87.16, 114.56 | APE8-rot-out | 184.74 | APE67-dihe-in | -62.01, -17.38 | -58.58, -38.0 | APE12-dist-out | 17.3988 | APE11-dist-out | 15.69 | APE10-dist-out | 10.5158 | APE9-dist-in | 5.6024 | I62L,L72R,V116I,G137K,F141Y,A146E | None | CME213 | XRAY | 1.6 | 0.16 | 0.186 | A | 328.0 | 321.0 | 0 | 27 | 27 | 0 | [[56, 307]] | 1.0 | 8uoj | Homo sapiens | CAMK_MARK3_HUMAN | CAMK | 5.9e-96 | 326.7 | 1.0 | 256.0 | 256.0 | 195 | 196 | 197 | 199 | 201 | 85 | 103 | 107 | 175 | 177 | 176 | 178.0 | 235 | 222 | 217 | 216 | 215 | 214 | 213 | 212 | 211 | 133 | MAP/microtubule affinity-regulating kinase 3 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|