PDB: 8UCB — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8UCBD

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8UCBA Q9NWZ3 164 459 460.0 X1T:501 Type1 Inactive DFGin 6.5864 13.5726 BLAminus -133.38, -177.12 64.35, 68.66 -97.8, 16.07 315.98, 102.93 -65.68, -24.73 in-out in 8.6022 Saltbr-out 4.6911 HRD-in -74.88, -51.2 76.87, -1.43 out-in-in SNCoii in-in ActLoopNT-in 2.7607 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.62, 153.75 APE9-dihe-na 131.02, 179.21 APE8-dihe-in -98.2, 123.02 APE8-rot-in 308.0 APE67-dihe-in -65.09, -13.5 -58.01, -44.66 APE12-dist-in 10.2847 APE11-dist-in 12.061 APE10-dist-in 6.9488 APE9-dist-in 4.5201 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.85 0.209 0.243 A 307.0 289.0 7 30 26 4 [[183, 456]] 1.0 8ucb TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBB Q9NWZ3 164 459 460.0 X1T:501 Type1 Inactive DFGin 6.6068 13.6491 BLAminus -133.65, -177.71 64.73, 70.02 -96.46, 15.08 312.24, 106.62 -64.34, -23.76 in-out in 8.4707 Saltbr-out 4.4017 HRD-in -75.17, -52.58 77.06, -2.05 out-in-in SNCoii in-in ActLoopNT-in 2.7252 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.68, 152.68 APE9-dihe-na 139.38, -177.32 APE8-dihe-in -102.85, 112.84 APE8-rot-in 315.95 APE67-dihe-in -69.47, -15.98 -65.94, -25.77 APE12-dist-in 10.0344 APE11-dist-in 12.218 APE10-dist-in 7.2634 APE9-dist-in 4.5061 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.85 0.209 0.243 B 307.0 288.0 8 30 24 6 [[183, 456]] 1.0 8ucb TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBC Q9NWZ3 164 459 460.0 X1T:501 Type1 Inactive DFGin 6.8619 13.6822 BLAminus -134.97, -176.91 65.3, 70.16 -98.18, 15.85 309.36, 103.91 -62.86, -30.38 in-out in 8.58 Saltbr-out 4.6734 HRD-in -73.7, -52.09 76.17, -2.4 out-in-in SNCoii in-in ActLoopNT-in 2.7491 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.82, 155.19 APE9-dihe-na 136.02, -175.98 APE8-dihe-in -107.53, 111.71 APE8-rot-in 310.29 APE67-dihe-in -67.32, -13.57 -61.09, -32.68 APE12-dist-in 10.0286 APE11-dist-in 11.8791 APE10-dist-in 6.6271 APE9-dist-in 4.3453 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.85 0.209 0.243 C 307.0 287.0 9 30 24 6 [[183, 456]] 1.0 8ucb TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBD Q9NWZ3 163 459 460.0 X1T:501 Type1 Inactive DFGin 6.6554 13.7707 BLAminus -133.17, -176.75 64.27, 71.56 -97.28, 15.93 311.73, 106.12 -63.94, -30.66 in-out in 8.6256 Saltbr-out 4.5655 HRD-in -70.95, -49.5 72.68, -1.18 out-in-in SNCoii in-in ActLoopNT-in 2.6741 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.88, 149.05 APE9-dihe-na 123.76, 174.28 APE8-dihe-in -91.74, 123.53 APE8-rot-in 308.1 APE67-dihe-in -62.24, -18.02 -60.37, -40.94 APE12-dist-in 10.2039 APE11-dist-in 11.968 APE10-dist-in 6.4738 APE9-dist-in 4.435 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.85 0.209 0.243 D 307.0 291.0 6 30 25 5 [[183, 456]] 1.0 8ucb TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8UCB — TKL IRAK4_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 8UCBD

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8UCBA Q9NWZ3 164 459 460.0 X1T:501 Type1 Inactive DFGin 6.5864 13.5726 BLAminus -133.38, -177.12 64.35, 68.66 -97.8, 16.07 315.98, 102.93 -65.68, -24.73 in-out in 8.6022 Saltbr-out 4.6911 HRD-in -74.88, -51.2 76.87, -1.43 out-in-in SNCoii in-in ActLoopNT-in 2.7607 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -130.62, 153.75 APE9-dihe-na 131.02, 179.21 APE8-dihe-in -98.2, 123.02 APE8-rot-in 308.0 APE67-dihe-in -65.09, -13.5 -58.01, -44.66 APE12-dist-in 10.2847 APE11-dist-in 12.061 APE10-dist-in 6.9488 APE9-dist-in 4.5201 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.85 0.209 0.243 A 307.0 289.0 7 30 26 4 [[183, 456]] 1.0 8ucb Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBB Q9NWZ3 164 459 460.0 X1T:501 Type1 Inactive DFGin 6.6068 13.6491 BLAminus -133.65, -177.71 64.73, 70.02 -96.46, 15.08 312.24, 106.62 -64.34, -23.76 in-out in 8.4707 Saltbr-out 4.4017 HRD-in -75.17, -52.58 77.06, -2.05 out-in-in SNCoii in-in ActLoopNT-in 2.7252 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -136.68, 152.68 APE9-dihe-na 139.38, -177.32 APE8-dihe-in -102.85, 112.84 APE8-rot-in 315.95 APE67-dihe-in -69.47, -15.98 -65.94, -25.77 APE12-dist-in 10.0344 APE11-dist-in 12.218 APE10-dist-in 7.2634 APE9-dist-in 4.5061 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.85 0.209 0.243 B 307.0 288.0 8 30 24 6 [[183, 456]] 1.0 8ucb Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBC Q9NWZ3 164 459 460.0 X1T:501 Type1 Inactive DFGin 6.8619 13.6822 BLAminus -134.97, -176.91 65.3, 70.16 -98.18, 15.85 309.36, 103.91 -62.86, -30.38 in-out in 8.58 Saltbr-out 4.6734 HRD-in -73.7, -52.09 76.17, -2.4 out-in-in SNCoii in-in ActLoopNT-in 2.7491 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -129.82, 155.19 APE9-dihe-na 136.02, -175.98 APE8-dihe-in -107.53, 111.71 APE8-rot-in 310.29 APE67-dihe-in -67.32, -13.57 -61.09, -32.68 APE12-dist-in 10.0286 APE11-dist-in 11.8791 APE10-dist-in 6.6271 APE9-dist-in 4.3453 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.85 0.209 0.243 C 307.0 287.0 9 30 24 6 [[183, 456]] 1.0 8ucb Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8UCBD Q9NWZ3 163 459 460.0 X1T:501 Type1 Inactive DFGin 6.6554 13.7707 BLAminus -133.17, -176.75 64.27, 71.56 -97.28, 15.93 311.73, 106.12 -63.94, -30.66 in-out in 8.6256 Saltbr-out 4.5655 HRD-in -70.95, -49.5 72.68, -1.18 out-in-in SNCoii in-in ActLoopNT-in 2.6741 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -126.88, 149.05 APE9-dihe-na 123.76, 174.28 APE8-dihe-in -91.74, 123.53 APE8-rot-in 308.1 APE67-dihe-in -62.24, -18.02 -60.37, -40.94 APE12-dist-in 10.2039 APE11-dist-in 11.968 APE10-dist-in 6.4738 APE9-dist-in 4.435 None TPO342,TPO345,SEP346 TPO342,TPO345,SEP346 XRAY 1.85 0.209 0.243 D 307.0 291.0 6 30 25 5 [[183, 456]] 1.0 8ucb Homo sapiens TKL_IRAK4_HUMAN TKL 4.4e-84 288.1 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8UCB — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name