PDB: 8TB6 — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8TB6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 8TB6A P29597 572 869 1187.0 ZOI:901 Type1 Pseudo DFGin 7.5187 12.9175 None -70.48, 163.05 -64.31, 156.7 -77.96, 2.63 25.15, 152.72 70.88, -150.51 in-na in 9.7566 Saltbr-na 999.0 HRD-in -88.04, -58.25 80.3, 7.16 na-out-out SNCaoo out-out ActLoopNT-out 8.0054 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -64.83, -38.13 APE9-dihe-out -58.13, -23.83 APE8-dihe-out -87.03, -4.8 APE8-rot-na 225.26 APE67-dihe-out -95.58, 10.52 -67.22, 136.28 APE12-dist-na 9.6696 APE11-dist-na 12.2145 APE10-dist-na 16.3433 APE9-dist-out 11.3389 None None None XRAY 1.96 0.195 0.236 A 326.0 263.0 33 24 24 0 [[589, 868], [897, 1171]] 2.0 8tb6 TYR_TYK2-1_HUMAN TYR 5.9e-60 208.8 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8TB6B P29597 580 867 1187.0 ZOI:901 Type1 Pseudo DFGin 7.5755 12.8341 None -75.19, 161.88 -63.62, 154.56 -77.31, 0.0 28.4, 144.85 69.85, -142.97 in-na in 9.7458 Saltbr-na 999.0 HRD-in -86.92, -60.13 92.81, -6.33 na-out-out SNCaoo out-out ActLoopNT-out 8.2289 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -58.54, -39.0 APE9-dihe-out -57.31, -25.9 APE8-dihe-out -87.7, -3.61 APE8-rot-na 309.71 APE67-dihe-out -99.75, 10.76 -63.68, 135.57 APE12-dist-na 9.794 APE11-dist-na 12.1163 APE10-dist-na 16.3342 APE9-dist-out 11.4309 None None None XRAY 1.96 0.195 0.236 B 326.0 254.0 35 24 24 0 [[589, 868], [897, 1171]] 2.0 8tb6 TYR_TYK2-1_HUMAN TYR 5.9e-60 208.8 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 8TB6 — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8TB6A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 8TB6A P29597 572 869 1187.0 ZOI:901 Type1 Pseudo DFGin 7.5187 12.9175 None -70.48, 163.05 -64.31, 156.7 -77.96, 2.63 25.15, 152.72 70.88, -150.51 in-na in 9.7566 Saltbr-na 999.0 HRD-in -88.04, -58.25 80.3, 7.16 na-out-out SNCaoo out-out ActLoopNT-out 8.0054 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -64.83, -38.13 APE9-dihe-out -58.13, -23.83 APE8-dihe-out -87.03, -4.8 APE8-rot-na 225.26 APE67-dihe-out -95.58, 10.52 -67.22, 136.28 APE12-dist-na 9.6696 APE11-dist-na 12.2145 APE10-dist-na 16.3433 APE9-dist-out 11.3389 None None None XRAY 1.96 0.195 0.236 A 326.0 263.0 33 24 24 0 [[589, 868], [897, 1171]] 2.0 8tb6 Homo sapiens TYR_TYK2-1_HUMAN TYR 5.9e-60 208.8 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8TB6B P29597 580 867 1187.0 ZOI:901 Type1 Pseudo DFGin 7.5755 12.8341 None -75.19, 161.88 -63.62, 154.56 -77.31, 0.0 28.4, 144.85 69.85, -142.97 in-na in 9.7458 Saltbr-na 999.0 HRD-in -86.92, -60.13 92.81, -6.33 na-out-out SNCaoo out-out ActLoopNT-out 8.2289 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -58.54, -39.0 APE9-dihe-out -57.31, -25.9 APE8-dihe-out -87.7, -3.61 APE8-rot-na 309.71 APE67-dihe-out -99.75, 10.76 -63.68, 135.57 APE12-dist-na 9.794 APE11-dist-na 12.1163 APE10-dist-na 16.3342 APE9-dist-out 11.4309 None None None XRAY 1.96 0.195 0.236 B 326.0 254.0 35 24 24 0 [[589, 868], [897, 1171]] 2.0 8tb6 Homo sapiens TYR_TYK2-1_HUMAN TYR 5.9e-60 208.8 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 8TB6 — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name