PDB: 8TB5 — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8TB5A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 8TB5A P29597 580 868 1187.0 ZOQ:902 Type1 Pseudo DFGin 7.5755 12.8276 None -72.9, 166.16 -62.82, 156.7 -75.2, -1.8 19.44, 155.05 65.85, -157.21 in-na in 9.6283 Saltbr-na 999.0 HRD-in -77.18, -55.68 90.86, -17.89 na-out-out SNCaoo out-out ActLoopNT-out 8.0333 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -58.91, -37.05 APE9-dihe-out -64.82, -24.45 APE8-dihe-out -87.22, -2.73 APE8-rot-na 294.55 APE67-dihe-out -99.67, 13.88 -62.74, 133.89 APE12-dist-na 9.9661 APE11-dist-na 12.452 APE10-dist-na 16.6371 APE9-dist-out 11.8185 None None None XRAY 2.32 0.187 0.243 A 326.0 257.0 32 24 24 0 [[589, 868], [897, 1171]] 2.0 8tb5 TYR_TYK2-1_HUMAN TYR 5.9e-60 208.8 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8TB5B P29597 580 868 1187.0 ZOQ:902 Type1 Pseudo DFGin 7.3538 12.8302 None -69.46, 162.15 -62.48, 155.25 -75.42, -2.04 28.22, 143.07 66.45, -159.8 in-na in 9.6545 Saltbr-na 999.0 HRD-in -80.42, -58.38 87.54, 2.75 na-out-out SNCaoo out-out ActLoopNT-out 8.229 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -60.71, -36.16 APE9-dihe-out -65.57, -18.78 APE8-dihe-out -89.43, 3.6 APE8-rot-na 301.67 APE67-dihe-out -95.11, 8.54 -67.3, 136.04 APE12-dist-na 10.0198 APE11-dist-na 12.281 APE10-dist-na 16.5002 APE9-dist-out 11.7261 None None None XRAY 2.32 0.187 0.243 B 326.0 257.0 32 24 24 0 [[589, 868], [897, 1171]] 2.0 8tb5 TYR_TYK2-1_HUMAN TYR 5.9e-60 208.8 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 8TB5 — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8TB5A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 8TB5A P29597 580 868 1187.0 ZOQ:902 Type1 Pseudo DFGin 7.5755 12.8276 None -72.9, 166.16 -62.82, 156.7 -75.2, -1.8 19.44, 155.05 65.85, -157.21 in-na in 9.6283 Saltbr-na 999.0 HRD-in -77.18, -55.68 90.86, -17.89 na-out-out SNCaoo out-out ActLoopNT-out 8.0333 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -58.91, -37.05 APE9-dihe-out -64.82, -24.45 APE8-dihe-out -87.22, -2.73 APE8-rot-na 294.55 APE67-dihe-out -99.67, 13.88 -62.74, 133.89 APE12-dist-na 9.9661 APE11-dist-na 12.452 APE10-dist-na 16.6371 APE9-dist-out 11.8185 None None None XRAY 2.32 0.187 0.243 A 326.0 257.0 32 24 24 0 [[589, 868], [897, 1171]] 2.0 8tb5 Homo sapiens TYR_TYK2-1_HUMAN TYR 5.9e-60 208.8 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 8TB5B P29597 580 868 1187.0 ZOQ:902 Type1 Pseudo DFGin 7.3538 12.8302 None -69.46, 162.15 -62.48, 155.25 -75.42, -2.04 28.22, 143.07 66.45, -159.8 in-na in 9.6545 Saltbr-na 999.0 HRD-in -80.42, -58.38 87.54, 2.75 na-out-out SNCaoo out-out ActLoopNT-out 8.229 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -60.71, -36.16 APE9-dihe-out -65.57, -18.78 APE8-dihe-out -89.43, 3.6 APE8-rot-na 301.67 APE67-dihe-out -95.11, 8.54 -67.3, 136.04 APE12-dist-na 10.0198 APE11-dist-na 12.281 APE10-dist-na 16.5002 APE9-dist-out 11.7261 None None None XRAY 2.32 0.187 0.243 B 326.0 257.0 32 24 24 0 [[589, 868], [897, 1171]] 2.0 8tb5 Homo sapiens TYR_TYK2-1_HUMAN TYR 5.9e-60 208.8 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 8TB5 — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name