PDB: 8S1A — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8S1AB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S1AA P10721 565 931 976.0 6T2:61001 Type1 Active DFGin 7.4808 13.4537 BLAminus -130.25, 174.66 66.24, 93.25 -105.72, 18.63 285.4, 75.09 -61.16, -30.32 in-in in 8.3211 Saltbr-in 3.005 HRD-in -89.71, -45.27 75.21, -0.98 in-in-in SNCiii in-in ActLoopNT-in 2.8512 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.31, 143.6 APE9-dihe-in -122.04, 151.68 APE8-dihe-in -82.91, 74.45 APE8-rot-na 35.68 APE67-dihe-in -72.93, -9.14 -57.9, -42.62 APE12-dist-na 13.9398 APE11-dist-na 9.4995 APE10-dist-na 12.9558 APE9-dist-in 7.5844 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.85 0.188 0.208 A 327.0 286.0 3 30 30 0 [[589, 926]] 1.0 8s1a TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1AB P10721 566 931 976.0 6T2:61001 Type1 Active DFGin 7.4323 13.5642 BLAminus -134.77, 174.81 62.68, 90.66 -103.62, 20.87 285.06, 74.67 -61.54, -35.7 in-in in 8.3104 Saltbr-in 2.716 HRD-in -95.21, -44.44 74.01, 0.64 in-in-in SNCiii in-in ActLoopNT-in 2.8065 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.03, 139.89 APE9-dihe-in -118.65, 149.04 APE8-dihe-in -82.35, 75.62 APE8-rot-na 34.69 APE67-dihe-in -73.13, -6.18 -57.98, -42.32 APE12-dist-na 14.1507 APE11-dist-na 9.6536 APE10-dist-na 13.1267 APE9-dist-in 7.6697 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.85 0.188 0.208 B 327.0 288.0 0 30 30 0 [[589, 926]] 1.0 8s1a TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S1A — TYR KIT_HUMAN

Total number of chains: 2
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8S1AB

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR KIT KIT_HUMAN 8S1AA P10721 565 931 976.0 6T2:61001 Type1 Active DFGin 7.4808 13.4537 BLAminus -130.25, 174.66 66.24, 93.25 -105.72, 18.63 285.4, 75.09 -61.16, -30.32 in-in in 8.3211 Saltbr-in 3.005 HRD-in -89.71, -45.27 75.21, -0.98 in-in-in SNCiii in-in ActLoopNT-in 2.8512 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -69.31, 143.6 APE9-dihe-in -122.04, 151.68 APE8-dihe-in -82.91, 74.45 APE8-rot-na 35.68 APE67-dihe-in -72.93, -9.14 -57.9, -42.62 APE12-dist-na 13.9398 APE11-dist-na 9.4995 APE10-dist-na 12.9558 APE9-dist-in 7.5844 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.85 0.188 0.208 A 327.0 286.0 3 30 30 0 [[589, 926]] 1.0 8s1a Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit
TYR KIT KIT_HUMAN 8S1AB P10721 566 931 976.0 6T2:61001 Type1 Active DFGin 7.4323 13.5642 BLAminus -134.77, 174.81 62.68, 90.66 -103.62, 20.87 285.06, 74.67 -61.54, -35.7 in-in in 8.3104 Saltbr-in 2.716 HRD-in -95.21, -44.44 74.01, 0.64 in-in-in SNCiii in-in ActLoopNT-in 2.8065 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.03, 139.89 APE9-dihe-in -118.65, 149.04 APE8-dihe-in -82.35, 75.62 APE8-rot-na 34.69 APE67-dihe-in -73.13, -6.18 -57.98, -42.32 APE12-dist-na 14.1507 APE11-dist-na 9.6536 APE10-dist-na 13.1267 APE9-dist-in 7.6697 I563S,V569S,Y609Q,L631S,M651E,I662H,D768H,R804N,V825D,C844S,L890S,H894Y,L912D,L923D None None XRAY 1.85 0.188 0.208 B 327.0 288.0 0 30 30 0 [[589, 926]] 1.0 8s1a Homo sapiens TYR_KIT_HUMAN TYR 2.3e-104 354.3 1.0 261.0 261.0 809 810 811 813 815 623 640 644 789 791 790 792.0 851 839 834 833 832 831 830 829 828 671 Mast/stem cell growth factor receptor Kit

PDB: 8S1A — TYR KIT_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name