8RRQ

SYK (Tyrosine-protein kinase SYK)
Group: TYR
Uniprot: KSYK_HUMAN
Organism: Homo sapiens
Domain boundary: 370 - 628
Resolu: 1.6

Chain id Activity_label Spatial_label Dihedral_label Chelix-SaltBridge ActLoopNT-ActLoopCT Ligand Type Residues in structure Unresolved residues in A-loop
A Active DFGin BLAminus in-in in-in A1H2W Type1 363 - 632 2
All chains
Pymol session(ver 2.3) Pymol script
All chains - renumbered by
Uniprot PDB Alignment 
Representative sequence - Chain A
       363        373        383        393 
gpeeirpkeV YLDRKLLTLE DKELGSGNFG TVKKGYYQMK 
       403        413        423        433 
KVVKTVAVKI LKNEANDPAL KDELLAEANV MQQLDNPYIV 
       443        453        463        473 
RMIGICEAES WMLVMEMAEL GPLNKYLQQN RHVKDKNIIE 
       483        493        503        513 
LVHQVSMGMK YLEESNFVHR DLAARNVLLV TQHYAKISDF 
       523        533        543        553 
GLSKALRADE NYYKAQthGK WPVKWYAPEC INYYKFSSKS 
       563        573        583        593 
DVWSFGVLMW EAFSYGQKPY RGMKGSEVTA MLEKGERMGC 
       603        613        623        633 
PAGCPREMYD LMNLCWTYDV ENRPGFAAVE LRLRNYYYDv 

vn
Lower-case residues are disordered in structure.
Mutations: None
Phosphorylation: X525,X526