PDB: 8R4O — CAMK SIK3_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 8R4OA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK SIK3 SIK3_HUMAN 8R4OA Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.789 14.519 BLAminus -125.71, 175.86 61.17, 85.12 -103.12, 32.38 284.88, 82.02 -69.13, -38.43 in-in in 9.211 Saltbr-in 2.707 HRD-in -68.78, -49.07 59.21, 16.18 in-in-out SNCiio in-out ActLoopNT-in 2.97 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.95, 164.22 APE9-dihe-na 138.1, 167.3 APE8-dihe-in -77.26, 120.01 APE8-rot-out 188.49 APE67-dihe-in -63.99, -17.85 -45.41, -48.19 APE12-dist-in 7.613 APE11-dist-in 11.08 APE10-dist-in 5.461 APE9-dist-in 3.338 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 A 328 316 0 0 0 0 [[66, 317]] 1.0 8r4o CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OC Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.828 14.447 BLAminus -129.55, 168.82 71.42, 83.09 -102.43, 31.89 286.31, 82.55 -67.62, -40.46 in-in in 9.165 Saltbr-in 2.644 HRD-in -65.95, -51.63 61.3, 16.73 in-in-out SNCiio in-out ActLoopNT-in 2.961 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.01, 164.27 APE9-dihe-na 137.9, 165.52 APE8-dihe-in -76.91, 120.34 APE8-rot-out 188.4 APE67-dihe-in -64.71, -17.77 -46.15, -47.73 APE12-dist-in 7.591 APE11-dist-in 11.054 APE10-dist-in 5.442 APE9-dist-in 3.369 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 C 328 315 0 0 0 0 [[66, 317]] 1.0 8r4o CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OE Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.939 14.597 BLAminus -125.14, 175.42 62.75, 84.83 -103.08, 31.64 285.5, 81.52 -67.98, -40.19 in-in in 9.121 Saltbr-in 2.636 HRD-in -67.61, -51.56 60.74, 18.57 in-in-out SNCiio in-out ActLoopNT-in 2.984 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.89, 164.3 APE9-dihe-na 136.57, 164.66 APE8-dihe-in -75.86, 119.82 APE8-rot-out 188.72 APE67-dihe-in -65.37, -17.85 -45.28, -48.13 APE12-dist-in 7.58 APE11-dist-in 11.062 APE10-dist-in 5.458 APE9-dist-in 3.39 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 E 328 315 0 0 0 0 [[66, 317]] 1.0 8r4o CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OG Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.91 14.615 BLAminus -124.38, 176.33 61.69, 84.93 -103.28, 30.5 286.01, 80.88 -68.19, -39.92 in-in in 9.182 Saltbr-in 2.866 HRD-in -70.7, -46.33 56.28, 19.08 in-in-out SNCiio in-out ActLoopNT-in 2.982 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.89, 164.45 APE9-dihe-na 136.64, 161.97 APE8-dihe-in -75.05, 120.57 APE8-rot-out 189.09 APE67-dihe-in -63.53, -18.35 -45.81, -48.67 APE12-dist-in 7.52 APE11-dist-in 11.021 APE10-dist-in 5.45 APE9-dist-in 3.395 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 G 328 323 0 0 0 0 [[66, 317]] 1.0 8r4o CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OI Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.899 14.565 BLAminus -132.68, 177.0 60.73, 84.44 -102.51, 32.39 285.22, 81.32 -69.52, -27.66 in-in in 9.194 Saltbr-in 2.714 HRD-in -82.53, -49.17 62.06, 18.27 in-in-out SNCiio in-out ActLoopNT-in 2.959 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.98, 164.61 APE9-dihe-na 136.93, 163.75 APE8-dihe-in -76.2, 120.78 APE8-rot-out 188.08 APE67-dihe-in -64.67, -17.51 -46.63, -48.17 APE12-dist-in 7.587 APE11-dist-in 11.079 APE10-dist-in 5.471 APE9-dist-in 3.381 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 I 328 317 0 0 0 0 [[66, 317]] 1.0 8r4o CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OK Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.973 14.783 BLAminus -128.99, 172.89 59.57, 78.9 -97.11, 33.89 284.36, 89.39 -70.96, -33.22 in-in in 9.212 Saltbr-in 2.733 HRD-in -72.38, -44.94 53.52, 24.05 in-in-out SNCiio in-out ActLoopNT-in 3.004 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -139.55, 165.44 APE9-dihe-na 135.73, 162.63 APE8-dihe-in -74.63, 117.97 APE8-rot-out 178.94 APE67-dihe-in -64.29, -16.62 -46.32, -48.14 APE12-dist-in 7.41 APE11-dist-in 10.926 APE10-dist-in 5.392 APE9-dist-in 3.295 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 K 328 316 0 0 0 0 [[66, 317]] 1.0 8r4o CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3

PDB: 8R4O — CAMK SIK3_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 6 100.0% 8R4OA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
CAMK SIK3 SIK3_HUMAN 8R4OA Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.789 14.519 BLAminus -125.71, 175.86 61.17, 85.12 -103.12, 32.38 284.88, 82.02 -69.13, -38.43 in-in in 9.211 Saltbr-in 2.707 HRD-in -68.78, -49.07 59.21, 16.18 in-in-out SNCiio in-out ActLoopNT-in 2.97 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.95, 164.22 APE9-dihe-na 138.1, 167.3 APE8-dihe-in -77.26, 120.01 APE8-rot-out 188.49 APE67-dihe-in -63.99, -17.85 -45.41, -48.19 APE12-dist-in 7.613 APE11-dist-in 11.08 APE10-dist-in 5.461 APE9-dist-in 3.338 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 A 328 316 0 0 0 0 [[66, 317]] 1.0 8r4o Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OC Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.828 14.447 BLAminus -129.55, 168.82 71.42, 83.09 -102.43, 31.89 286.31, 82.55 -67.62, -40.46 in-in in 9.165 Saltbr-in 2.644 HRD-in -65.95, -51.63 61.3, 16.73 in-in-out SNCiio in-out ActLoopNT-in 2.961 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.01, 164.27 APE9-dihe-na 137.9, 165.52 APE8-dihe-in -76.91, 120.34 APE8-rot-out 188.4 APE67-dihe-in -64.71, -17.77 -46.15, -47.73 APE12-dist-in 7.591 APE11-dist-in 11.054 APE10-dist-in 5.442 APE9-dist-in 3.369 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 C 328 315 0 0 0 0 [[66, 317]] 1.0 8r4o Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OE Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.939 14.597 BLAminus -125.14, 175.42 62.75, 84.83 -103.08, 31.64 285.5, 81.52 -67.98, -40.19 in-in in 9.121 Saltbr-in 2.636 HRD-in -67.61, -51.56 60.74, 18.57 in-in-out SNCiio in-out ActLoopNT-in 2.984 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.89, 164.3 APE9-dihe-na 136.57, 164.66 APE8-dihe-in -75.86, 119.82 APE8-rot-out 188.72 APE67-dihe-in -65.37, -17.85 -45.28, -48.13 APE12-dist-in 7.58 APE11-dist-in 11.062 APE10-dist-in 5.458 APE9-dist-in 3.39 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 E 328 315 0 0 0 0 [[66, 317]] 1.0 8r4o Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OG Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.91 14.615 BLAminus -124.38, 176.33 61.69, 84.93 -103.28, 30.5 286.01, 80.88 -68.19, -39.92 in-in in 9.182 Saltbr-in 2.866 HRD-in -70.7, -46.33 56.28, 19.08 in-in-out SNCiio in-out ActLoopNT-in 2.982 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.89, 164.45 APE9-dihe-na 136.64, 161.97 APE8-dihe-in -75.05, 120.57 APE8-rot-out 189.09 APE67-dihe-in -63.53, -18.35 -45.81, -48.67 APE12-dist-in 7.52 APE11-dist-in 11.021 APE10-dist-in 5.45 APE9-dist-in 3.395 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 G 328 323 0 0 0 0 [[66, 317]] 1.0 8r4o Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OI Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.899 14.565 BLAminus -132.68, 177.0 60.73, 84.44 -102.51, 32.39 285.22, 81.32 -69.52, -27.66 in-in in 9.194 Saltbr-in 2.714 HRD-in -82.53, -49.17 62.06, 18.27 in-in-out SNCiio in-out ActLoopNT-in 2.959 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -137.98, 164.61 APE9-dihe-na 136.93, 163.75 APE8-dihe-in -76.2, 120.78 APE8-rot-out 188.08 APE67-dihe-in -64.67, -17.51 -46.63, -48.17 APE12-dist-in 7.587 APE11-dist-in 11.079 APE10-dist-in 5.471 APE9-dist-in 3.381 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 I 328 317 0 0 0 0 [[66, 317]] 1.0 8r4o Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3
CAMK SIK3 SIK3_HUMAN 8R4OK Q9Y2K2 62 384 1321.0 XVI:401 Type1 Inactive DFGin 6.973 14.783 BLAminus -128.99, 172.89 59.57, 78.9 -97.11, 33.89 284.36, 89.39 -70.96, -33.22 in-in in 9.212 Saltbr-in 2.733 HRD-in -72.38, -44.94 53.52, 24.05 in-in-out SNCiio in-out ActLoopNT-in 3.004 ActLoopCT-out nonTYR APEdihe_aaioi APEdist_iiii APE10-dihe-na -139.55, 165.44 APE9-dihe-na 135.73, 162.63 APE8-dihe-in -74.63, 117.97 APE8-rot-out 178.94 APE67-dihe-in -64.29, -16.62 -46.32, -48.14 APE12-dist-in 7.41 APE11-dist-in 10.926 APE10-dist-in 5.392 APE9-dist-in 3.295 C121S,C181S,C333S TPO221 TPO221 XRAY 2.725 0.216 0.244 K 328 316 0 0 0 0 [[66, 317]] 1.0 8r4o Homo sapiens CAMK_SIK3_HUMAN CAMK 1.8e-96 328.4 1 256 256 205 206 207 209 211 95 113 117 185 187 186 188 245 232 227 226 225 224 223 222 221 143 Serine/threonine-protein kinase SIK3

PDB: 8R4O — CAMK SIK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name