| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | IGF1R | IGF1R_HUMAN | 8PYIAAA | P08069 | 986 | 1286 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.1834 | 12.5096 | None | -115.76, -140.08 | -56.69, 128.49 | -118.25, -19.27 | 59.93, 80.29 | -40.9, -38.76 | out-out | out | 10.5805 | Saltbr-out | 8.1365 | HRD-in | -71.36, -56.99 | 87.46, -13.56 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.9222 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 111.18 | APE9-dihe-in | -126.65, 126.64 | APE8-dihe-in | -81.12, 76.62 | APE8-rot-na | 35.9 | APE67-dihe-in | -71.26, -20.53 | -54.98, -37.02 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.1722 | APE9-dist-in | 7.0729 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | AAA | 321.0 | 288.0 | 13 | 30 | 25 | 5 | [[999, 1268]] | 1.0 | 8pyi | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIBBB | P08069 | 986 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2198 | 12.4468 | None | -115.29, -140.05 | -57.59, 130.35 | -119.47, -19.04 | 57.6, 81.65 | -39.33, -40.51 | out-out | out | 10.5812 | Saltbr-out | 8.1383 | HRD-in | -71.54, -57.15 | 87.92, -15.23 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.9933 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 112.31 | APE9-dihe-in | -126.67, 128.52 | APE8-dihe-in | -80.09, 76.32 | APE8-rot-na | 35.62 | APE67-dihe-in | -70.72, -20.09 | -56.2, -36.65 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.1097 | APE9-dist-in | 7.0678 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | BBB | 321.0 | 287.0 | 13 | 30 | 25 | 5 | [[999, 1268]] | 1.0 | 8pyi | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYICCC | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.1658 | 12.5055 | None | -114.85, -140.89 | -57.29, 129.65 | -118.38, -19.22 | 58.71, 80.33 | -40.35, -39.19 | out-out | out | 10.5475 | Saltbr-out | 8.0781 | HRD-in | -70.97, -56.86 | 87.86, -15.93 | out-out-in | SNCooi | out-in | ActLoopNT-out | 8.949 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -146.69, 116.05 | APE9-dihe-in | -129.59, 126.27 | APE8-dihe-in | -80.63, 76.08 | APE8-rot-na | 36.39 | APE67-dihe-in | -71.13, -19.68 | -54.93, -37.06 | APE12-dist-na | 999.0 | APE11-dist-na | 9.6528 | APE10-dist-na | 6.1837 | APE9-dist-in | 7.1311 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | CCC | 321.0 | 286.0 | 13 | 30 | 25 | 5 | [[999, 1268]] | 1.0 | 8pyi | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIDDD | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2193 | 12.4591 | None | -115.04, -139.19 | -57.22, 129.11 | -118.66, -19.63 | 58.67, 81.12 | -40.31, -39.48 | out-out | out | 10.6051 | Saltbr-out | 8.0953 | HRD-in | -71.24, -57.12 | 86.84, -13.26 | out-out-in | SNCooi | out-in | ActLoopNT-out | 8.9353 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -91.29, 122.24 | APE9-dihe-in | -125.14, 125.87 | APE8-dihe-in | -79.9, 75.59 | APE8-rot-na | 36.0 | APE67-dihe-in | -70.95, -19.69 | -56.73, -36.41 | APE12-dist-na | 999.0 | APE11-dist-na | 9.5534 | APE10-dist-na | 5.9864 | APE9-dist-in | 7.1246 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | DDD | 321.0 | 287.0 | 12 | 30 | 26 | 4 | [[999, 1268]] | 1.0 | 8pyi | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIEEE | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2696 | 12.4395 | None | -115.61, -138.87 | -56.86, 128.87 | -118.49, -19.41 | 58.83, 81.0 | -40.15, -38.87 | out-out | out | 10.5158 | Saltbr-out | 8.0918 | HRD-in | -71.39, -56.94 | 87.82, -14.48 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.9511 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 116.42 | APE9-dihe-in | -125.67, 127.35 | APE8-dihe-in | -81.15, 76.83 | APE8-rot-na | 35.52 | APE67-dihe-in | -70.81, -19.39 | -56.95, -36.98 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.1552 | APE9-dist-in | 7.1131 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | EEE | 321.0 | 285.0 | 14 | 30 | 24 | 6 | [[999, 1268]] | 1.0 | 8pyi | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIFFF | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.3096 | 12.5061 | None | -114.84, -139.12 | -57.32, 129.09 | -119.24, -19.1 | 58.43, 80.95 | -39.6, -40.34 | out-out | out | 10.5617 | Saltbr-out | 8.089 | HRD-in | -71.51, -57.69 | 87.61, -14.16 | out-out-in | SNCooi | out-in | ActLoopNT-out | 8.9132 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -146.97, 119.39 | APE9-dihe-in | -127.92, 126.81 | APE8-dihe-in | -81.17, 76.54 | APE8-rot-na | 34.85 | APE67-dihe-in | -70.74, -20.02 | -56.2, -36.99 | APE12-dist-na | 14.2666 | APE11-dist-na | 9.7045 | APE10-dist-na | 6.1759 | APE9-dist-in | 7.0714 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | FFF | 321.0 | 287.0 | 12 | 30 | 27 | 3 | [[999, 1268]] | 1.0 | 8pyi | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIGGG | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2153 | 12.4108 | None | -115.39, -138.9 | -56.85, 128.81 | -118.89, -19.11 | 58.65, 81.01 | -40.57, -39.34 | out-out | out | 10.5825 | Saltbr-out | 8.1508 | HRD-in | -71.45, -56.87 | 87.79, -13.89 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.956 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 115.56 | APE9-dihe-in | -139.88, 129.5 | APE8-dihe-in | -81.92, 78.52 | APE8-rot-na | 36.73 | APE67-dihe-in | -71.48, -19.02 | -54.63, -36.81 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.3133 | APE9-dist-in | 6.9254 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | GGG | 321.0 | 284.0 | 15 | 30 | 24 | 6 | [[999, 1268]] | 1.0 | 8pyi | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIHHH | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2008 | 12.4942 | None | -116.04, -140.1 | -57.52, 129.83 | -118.81, -19.1 | 57.82, 80.84 | -40.32, -39.43 | out-out | out | 10.6159 | Saltbr-out | 8.1215 | HRD-in | -71.69, -57.04 | 87.53, -14.25 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.9588 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 112.91 | APE9-dihe-in | -126.66, 127.03 | APE8-dihe-in | -79.81, 75.92 | APE8-rot-na | 35.31 | APE67-dihe-in | -70.25, -19.75 | -57.25, -36.61 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.1541 | APE9-dist-in | 7.1652 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | HHH | 321.0 | 285.0 | 14 | 30 | 25 | 5 | [[999, 1268]] | 1.0 | 8pyi | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | IGF1R | IGF1R_HUMAN | 8PYIAAA | P08069 | 986 | 1286 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.1834 | 12.5096 | None | -115.76, -140.08 | -56.69, 128.49 | -118.25, -19.27 | 59.93, 80.29 | -40.9, -38.76 | out-out | out | 10.5805 | Saltbr-out | 8.1365 | HRD-in | -71.36, -56.99 | 87.46, -13.56 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.9222 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 111.18 | APE9-dihe-in | -126.65, 126.64 | APE8-dihe-in | -81.12, 76.62 | APE8-rot-na | 35.9 | APE67-dihe-in | -71.26, -20.53 | -54.98, -37.02 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.1722 | APE9-dist-in | 7.0729 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | AAA | 321.0 | 288.0 | 13 | 30 | 25 | 5 | [[999, 1268]] | 1.0 | 8pyi | Homo sapiens | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIBBB | P08069 | 986 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2198 | 12.4468 | None | -115.29, -140.05 | -57.59, 130.35 | -119.47, -19.04 | 57.6, 81.65 | -39.33, -40.51 | out-out | out | 10.5812 | Saltbr-out | 8.1383 | HRD-in | -71.54, -57.15 | 87.92, -15.23 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.9933 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 112.31 | APE9-dihe-in | -126.67, 128.52 | APE8-dihe-in | -80.09, 76.32 | APE8-rot-na | 35.62 | APE67-dihe-in | -70.72, -20.09 | -56.2, -36.65 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.1097 | APE9-dist-in | 7.0678 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | BBB | 321.0 | 287.0 | 13 | 30 | 25 | 5 | [[999, 1268]] | 1.0 | 8pyi | Homo sapiens | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYICCC | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.1658 | 12.5055 | None | -114.85, -140.89 | -57.29, 129.65 | -118.38, -19.22 | 58.71, 80.33 | -40.35, -39.19 | out-out | out | 10.5475 | Saltbr-out | 8.0781 | HRD-in | -70.97, -56.86 | 87.86, -15.93 | out-out-in | SNCooi | out-in | ActLoopNT-out | 8.949 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -146.69, 116.05 | APE9-dihe-in | -129.59, 126.27 | APE8-dihe-in | -80.63, 76.08 | APE8-rot-na | 36.39 | APE67-dihe-in | -71.13, -19.68 | -54.93, -37.06 | APE12-dist-na | 999.0 | APE11-dist-na | 9.6528 | APE10-dist-na | 6.1837 | APE9-dist-in | 7.1311 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | CCC | 321.0 | 286.0 | 13 | 30 | 25 | 5 | [[999, 1268]] | 1.0 | 8pyi | Homo sapiens | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIDDD | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2193 | 12.4591 | None | -115.04, -139.19 | -57.22, 129.11 | -118.66, -19.63 | 58.67, 81.12 | -40.31, -39.48 | out-out | out | 10.6051 | Saltbr-out | 8.0953 | HRD-in | -71.24, -57.12 | 86.84, -13.26 | out-out-in | SNCooi | out-in | ActLoopNT-out | 8.9353 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -91.29, 122.24 | APE9-dihe-in | -125.14, 125.87 | APE8-dihe-in | -79.9, 75.59 | APE8-rot-na | 36.0 | APE67-dihe-in | -70.95, -19.69 | -56.73, -36.41 | APE12-dist-na | 999.0 | APE11-dist-na | 9.5534 | APE10-dist-na | 5.9864 | APE9-dist-in | 7.1246 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | DDD | 321.0 | 287.0 | 12 | 30 | 26 | 4 | [[999, 1268]] | 1.0 | 8pyi | Homo sapiens | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIEEE | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2696 | 12.4395 | None | -115.61, -138.87 | -56.86, 128.87 | -118.49, -19.41 | 58.83, 81.0 | -40.15, -38.87 | out-out | out | 10.5158 | Saltbr-out | 8.0918 | HRD-in | -71.39, -56.94 | 87.82, -14.48 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.9511 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 116.42 | APE9-dihe-in | -125.67, 127.35 | APE8-dihe-in | -81.15, 76.83 | APE8-rot-na | 35.52 | APE67-dihe-in | -70.81, -19.39 | -56.95, -36.98 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.1552 | APE9-dist-in | 7.1131 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | EEE | 321.0 | 285.0 | 14 | 30 | 24 | 6 | [[999, 1268]] | 1.0 | 8pyi | Homo sapiens | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIFFF | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.3096 | 12.5061 | None | -114.84, -139.12 | -57.32, 129.09 | -119.24, -19.1 | 58.43, 80.95 | -39.6, -40.34 | out-out | out | 10.5617 | Saltbr-out | 8.089 | HRD-in | -71.51, -57.69 | 87.61, -14.16 | out-out-in | SNCooi | out-in | ActLoopNT-out | 8.9132 | ActLoopCT-in | TYR | APEdihe_iiiai | APEdist_aaai | APE10-dihe-in | -146.97, 119.39 | APE9-dihe-in | -127.92, 126.81 | APE8-dihe-in | -81.17, 76.54 | APE8-rot-na | 34.85 | APE67-dihe-in | -70.74, -20.02 | -56.2, -36.99 | APE12-dist-na | 14.2666 | APE11-dist-na | 9.7045 | APE10-dist-na | 6.1759 | APE9-dist-in | 7.0714 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | FFF | 321.0 | 287.0 | 12 | 30 | 27 | 3 | [[999, 1268]] | 1.0 | 8pyi | Homo sapiens | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIGGG | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2153 | 12.4108 | None | -115.39, -138.9 | -56.85, 128.81 | -118.89, -19.11 | 58.65, 81.01 | -40.57, -39.34 | out-out | out | 10.5825 | Saltbr-out | 8.1508 | HRD-in | -71.45, -56.87 | 87.79, -13.89 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.956 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 115.56 | APE9-dihe-in | -139.88, 129.5 | APE8-dihe-in | -81.92, 78.52 | APE8-rot-na | 36.73 | APE67-dihe-in | -71.48, -19.02 | -54.63, -36.81 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.3133 | APE9-dist-in | 6.9254 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | GGG | 321.0 | 284.0 | 15 | 30 | 24 | 6 | [[999, 1268]] | 1.0 | 8pyi | Homo sapiens | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| TYR | IGF1R | IGF1R_HUMAN | 8PYIHHH | P08069 | 987 | 1285 | 1367.0 | IER:3000 | Type1.5_Front | Inactive | DFGin | 6.2008 | 12.4942 | None | -116.04, -140.1 | -57.52, 129.83 | -118.81, -19.1 | 57.82, 80.84 | -40.32, -39.43 | out-out | out | 10.6159 | Saltbr-out | 8.1215 | HRD-in | -71.69, -57.04 | 87.53, -14.25 | out-out-none | SNCoon | out-none | ActLoopNT-out | 8.9588 | ActLoopCT-none | TYR | APEdihe_niiai | APEdist_aaai | APE10-dihe-none | 999.0, 112.91 | APE9-dihe-in | -126.66, 127.03 | APE8-dihe-in | -79.81, 75.92 | APE8-rot-na | 35.31 | APE67-dihe-in | -70.25, -19.75 | -57.25, -36.61 | APE12-dist-na | 999.0 | APE11-dist-na | 999.0 | APE10-dist-na | 6.1541 | APE9-dist-in | 7.1652 | None | None | None | XRAY | 3.06 | 0.193 | 0.235 | HHH | 321.0 | 285.0 | 14 | 30 | 25 | 5 | [[999, 1268]] | 1.0 | 8pyi | Homo sapiens | TYR_IGF1R_HUMAN | TYR | 2.3e-95 | 324.8 | 1.0 | 260.0 | 260.0 | 1152 | 1153 | 1154 | 1156 | 1158 | 1033 | 1050 | 1054 | 1132 | 1134 | 1133 | 1135.0 | 1194 | 1182 | 1177 | 1176 | 1175 | 1174 | 1173 | 1172 | 1171 | 1080 | Insulin-like growth factor 1 receptor |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|