PDB: 8H7X — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8H7XA
DFGinter None 1 50.0% 8H7XB
All chains - renumbered by
Uniprot PDB Alignment

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8H7XA P00533 697 1019 1210.0 6GY:1500 Type1 Active DFGin 5.635 13.772 BLAminus -162.89, 168.84 77.21, 81.71 -97.92, 23.57 309.06, 76.3 -58.42, -31.29 in-in in 8.899 Saltbr-in 3.163 HRD-in -78.19, -35.41 64.93, 5.25 in-in-in SNCiii in-in ActLoopNT-in 3.032 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -124.33, 109.95 APE9-dihe-in -128.71, 142.43 APE8-dihe-in -73.85, 112.86 APE8-rot-na 33.56 APE67-dihe-in -80.76, -11.68 -63.25, -24.22 APE12-dist-na 12.291 APE11-dist-na 9.112 APE10-dist-na 10.289 APE9-dist-in 6.269 T790M,C797S None None XRAY 3.404 0.189 0.256 A 330 299 0 0 0 0 [[712, 970]] 1.0 8h7x TYR_EGFR_HUMAN TYR 6.2e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8H7XB P00533 697 1018 1210.0 No_ligand No_ligand Inactive DFGinter 8.474 4.539 None -64.56, 138.69 -118.16, 46.75 -84.7, 147.88 264.74, 132.9 65.94, 48.18 in-in in 7.861 Saltbr-in 2.743 HRD-in -95.26, -40.89 71.41, -6.98 in-out-none SNCion out-none ActLoopNT-out 5.284 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.76 APE8-dihe-in -79.73, 83.74 APE8-rot-na 34.28 APE67-dihe-in -52.0, -45.23 -70.34, -44.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.766 T790M,C797S None None XRAY 3.404 0.189 0.256 B 330 304 7 0 0 7 [[712, 970]] 1.0 8h7x TYR_EGFR_HUMAN TYR 6.2e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8H7X — TYR EGFR_HUMAN

Total number of chains: 2
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 1 50.0% 8H7XA
DFGinter None 1 50.0% 8H7XB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8H7XA P00533 697 1019 1210.0 6GY:1500 Type1 Active DFGin 5.635 13.772 BLAminus -162.89, 168.84 77.21, 81.71 -97.92, 23.57 309.06, 76.3 -58.42, -31.29 in-in in 8.899 Saltbr-in 3.163 HRD-in -78.19, -35.41 64.93, 5.25 in-in-in SNCiii in-in ActLoopNT-in 3.032 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -124.33, 109.95 APE9-dihe-in -128.71, 142.43 APE8-dihe-in -73.85, 112.86 APE8-rot-na 33.56 APE67-dihe-in -80.76, -11.68 -63.25, -24.22 APE12-dist-na 12.291 APE11-dist-na 9.112 APE10-dist-na 10.289 APE9-dist-in 6.269 T790M,C797S None None XRAY 3.404 0.189 0.256 A 330 299 0 0 0 0 [[712, 970]] 1.0 8h7x Homo sapiens TYR_EGFR_HUMAN TYR 6.2e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8H7XB P00533 697 1018 1210.0 No_ligand No_ligand Inactive DFGinter 8.474 4.539 None -64.56, 138.69 -118.16, 46.75 -84.7, 147.88 264.74, 132.9 65.94, 48.18 in-in in 7.861 Saltbr-in 2.743 HRD-in -95.26, -40.89 71.41, -6.98 in-out-none SNCion out-none ActLoopNT-out 5.284 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.76 APE8-dihe-in -79.73, 83.74 APE8-rot-na 34.28 APE67-dihe-in -52.0, -45.23 -70.34, -44.7 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.766 T790M,C797S None None XRAY 3.404 0.189 0.256 B 330 304 7 0 0 7 [[712, 970]] 1.0 8h7x Homo sapiens TYR_EGFR_HUMAN TYR 6.2e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8H7X — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name