PDB: 8G8O — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8G8OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8G8OA O60674 842 1130 1132.0 YT0:1201 Type1 Inactive DFGin 6.2024 13.3615 ABAminus -120.55, -4.2 -147.29, 140.78 -131.57, 35.21 298.42, 95.45 -70.36, -19.76 in-in in 8.1921 Saltbr-in 2.533 HRD-in -67.5, -52.92 71.36, 0.27 in-in-in SNCiii in-in ActLoopNT-in 2.7169 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -53.6, 147.72 APE9-dihe-in -134.85, 143.13 APE8-dihe-in -73.21, 78.3 APE8-rot-na 29.04 APE67-dihe-in -74.11, 1.81 -65.23, -33.21 APE12-dist-na 13.8977 APE11-dist-na 10.893 APE10-dist-na 12.1092 APE9-dist-in 7.4368 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.2 0.189 0.231 A 318.0 282.0 7 31 31 0 [[545, 807], [849, 1125]] 2.0 8g8o TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8OB O60674 843 1130 1132.0 YT0:1201 Type1 Inactive DFGin 6.1952 13.4562 ABAminus -116.17, -2.6 -150.03, 138.73 -130.97, 33.74 298.07, 97.39 -67.58, -22.65 in-in in 8.3026 Saltbr-in 2.5 HRD-in -66.68, -51.5 71.43, 0.69 in-in-none SNCiin in-none ActLoopNT-in 2.7336 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 153.39 APE9-dihe-in -126.18, 143.79 APE8-dihe-in -69.22, 78.32 APE8-rot-na 30.12 APE67-dihe-in -74.43, 0.93 -67.38, -32.46 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.8301 APE9-dist-in 7.6555 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.2 0.189 0.231 B 318.0 279.0 9 31 28 3 [[545, 807], [849, 1125]] 2.0 8g8o TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 8G8O — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8G8OA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8G8OA O60674 842 1130 1132.0 YT0:1201 Type1 Inactive DFGin 6.2024 13.3615 ABAminus -120.55, -4.2 -147.29, 140.78 -131.57, 35.21 298.42, 95.45 -70.36, -19.76 in-in in 8.1921 Saltbr-in 2.533 HRD-in -67.5, -52.92 71.36, 0.27 in-in-in SNCiii in-in ActLoopNT-in 2.7169 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -53.6, 147.72 APE9-dihe-in -134.85, 143.13 APE8-dihe-in -73.21, 78.3 APE8-rot-na 29.04 APE67-dihe-in -74.11, 1.81 -65.23, -33.21 APE12-dist-na 13.8977 APE11-dist-na 10.893 APE10-dist-na 12.1092 APE9-dist-in 7.4368 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.2 0.189 0.231 A 318.0 282.0 7 31 31 0 [[545, 807], [849, 1125]] 2.0 8g8o Homo sapiens TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G8OB O60674 843 1130 1132.0 YT0:1201 Type1 Inactive DFGin 6.1952 13.4562 ABAminus -116.17, -2.6 -150.03, 138.73 -130.97, 33.74 298.07, 97.39 -67.58, -22.65 in-in in 8.3026 Saltbr-in 2.5 HRD-in -66.68, -51.5 71.43, 0.69 in-in-none SNCiin in-none ActLoopNT-in 2.7336 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 153.39 APE9-dihe-in -126.18, 143.79 APE8-dihe-in -69.22, 78.32 APE8-rot-na 30.12 APE67-dihe-in -74.43, 0.93 -67.38, -32.46 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 12.8301 APE9-dist-in 7.6555 M1073S,F1076T PTR1007,PTR1008 PTR1007,PTR1008 XRAY 2.2 0.189 0.231 B 318.0 279.0 9 31 28 3 [[545, 807], [849, 1125]] 2.0 8g8o Homo sapiens TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 8G8O — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name