PDB: 8G6Z — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8G6ZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8G6ZA O60674 843 1131 1132.0 YSI:1201 Type1 Inactive DFGin 6.5066 13.4808 ABAminus -112.8, -5.23 -143.49, 146.77 -138.83, 38.03 298.53, 91.36 -63.83, -28.22 in-in in 8.1795 Saltbr-in 2.5487 HRD-in -65.64, -52.64 73.67, 5.8 in-in-in SNCiii in-in ActLoopNT-in 2.945 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.74, 129.64 APE9-dihe-in -136.21, 150.63 APE8-dihe-in -82.42, 71.95 APE8-rot-na 35.87 APE67-dihe-in -78.82, 3.44 -55.51, -28.44 APE12-dist-na 9.9833 APE11-dist-na 10.9562 APE10-dist-na 12.3315 APE9-dist-in 7.4526 M1073S,F1076T PTR1007 PTR1007 XRAY 2.45 0.228 0.281 A 318.0 281.0 8 31 29 2 [[545, 807], [849, 1125]] 2.0 8g6z TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G6ZB O60674 843 1131 1132.0 YSI:1201 Type1 Inactive DFGin 6.4784 13.5187 ABAminus -114.28, -24.13 -123.15, 146.92 -135.04, 38.65 297.12, 87.98 -64.32, -25.66 in-in in 8.3282 Saltbr-in 2.5339 HRD-in -64.88, -55.1 79.03, -3.13 in-in-in SNCiii in-in ActLoopNT-in 2.9482 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.77, 129.6 APE9-dihe-in -136.97, 149.24 APE8-dihe-in -83.09, 73.37 APE8-rot-na 34.87 APE67-dihe-in -79.65, 4.6 -55.74, -28.56 APE12-dist-na 10.3868 APE11-dist-na 10.7927 APE10-dist-na 11.9784 APE9-dist-in 7.4146 M1073S,F1076T PTR1007 PTR1007 XRAY 2.45 0.228 0.281 B 318.0 280.0 9 31 29 2 [[545, 807], [849, 1125]] 2.0 8g6z TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 8G6Z — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8G6ZA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8G6ZA O60674 843 1131 1132.0 YSI:1201 Type1 Inactive DFGin 6.5066 13.4808 ABAminus -112.8, -5.23 -143.49, 146.77 -138.83, 38.03 298.53, 91.36 -63.83, -28.22 in-in in 8.1795 Saltbr-in 2.5487 HRD-in -65.64, -52.64 73.67, 5.8 in-in-in SNCiii in-in ActLoopNT-in 2.945 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.74, 129.64 APE9-dihe-in -136.21, 150.63 APE8-dihe-in -82.42, 71.95 APE8-rot-na 35.87 APE67-dihe-in -78.82, 3.44 -55.51, -28.44 APE12-dist-na 9.9833 APE11-dist-na 10.9562 APE10-dist-na 12.3315 APE9-dist-in 7.4526 M1073S,F1076T PTR1007 PTR1007 XRAY 2.45 0.228 0.281 A 318.0 281.0 8 31 29 2 [[545, 807], [849, 1125]] 2.0 8g6z Homo sapiens TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8G6ZB O60674 843 1131 1132.0 YSI:1201 Type1 Inactive DFGin 6.4784 13.5187 ABAminus -114.28, -24.13 -123.15, 146.92 -135.04, 38.65 297.12, 87.98 -64.32, -25.66 in-in in 8.3282 Saltbr-in 2.5339 HRD-in -64.88, -55.1 79.03, -3.13 in-in-in SNCiii in-in ActLoopNT-in 2.9482 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -70.77, 129.6 APE9-dihe-in -136.97, 149.24 APE8-dihe-in -83.09, 73.37 APE8-rot-na 34.87 APE67-dihe-in -79.65, 4.6 -55.74, -28.56 APE12-dist-na 10.3868 APE11-dist-na 10.7927 APE10-dist-na 11.9784 APE9-dist-in 7.4146 M1073S,F1076T PTR1007 PTR1007 XRAY 2.45 0.228 0.281 B 318.0 280.0 9 31 29 2 [[545, 807], [849, 1125]] 2.0 8g6z Homo sapiens TYR_JAK2-2_HUMAN TYR 7.8e-87 296.9 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 8G6Z — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name