PDB: 8FV4 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8FV4C
DFGin BLBtrans 2 50.0% 8FV4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8FV4C P00533 702 1013 1210.0 ANP:1102 ATPlike Inactive DFGin 4.0815 13.5578 BLBplus -127.73, 168.23 73.07, 11.78 -61.24, 145.82 61.45, 98.91 81.41, -31.2 out-out out 13.7417 Saltbr-out 16.1154 HRD-in -67.13, -63.64 88.26, -13.01 out-out-out SNCooo out-out ActLoopNT-out 6.5839 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -45.21, -49.43 APE9-dihe-in -74.91, 126.99 APE8-dihe-in -76.17, 58.7 APE8-rot-na 28.97 APE67-dihe-in -74.88, -4.9 -52.62, -40.92 APE12-dist-na 999.0 APE11-dist-na 16.2617 APE10-dist-na 12.2316 APE9-dist-out 8.1002 T790M,V948R None None XRAY 2.2 0.204 0.261 C 328.0 296.0 11 30 19 11 [[712, 970]] 1.0 8fv4 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4D P00533 701 1005 1210.0 YAA:1101 Type1.5_Back Inactive DFGin 4.3363 14.1928 BLBplus -131.61, 167.63 65.73, 30.81 -71.32, 133.31 54.39, 91.6 84.61, 0.99 out-out out 13.9441 Saltbr-out 12.4326 HRD-in -68.84, -58.76 79.63, -1.53 out-out-none SNCoon out-none ActLoopNT-out 7.0831 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 100.68 APE8-dihe-in -73.69, 77.18 APE8-rot-na 31.74 APE67-dihe-in -70.65, -4.38 -67.28, -33.85 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8152 T790M,V948R None None XRAY 2.2 0.204 0.261 D 328.0 291.0 14 30 17 13 [[712, 970]] 1.0 8fv4 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4A P00533 701 1013 1210.0 ANP:1102 ATPlike Inactive DFGin 5.115 16.0834 BLBtrans -131.04, 178.71 63.39, 21.89 -65.77, 133.12 153.56, 67.25 81.77, -5.74 out-out out 13.9648 Saltbr-out 14.3656 HRD-in -75.29, -65.35 93.54, -10.41 out-out-out SNCooo out-out ActLoopNT-out 6.6138 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 123.22 APE8-dihe-in -79.99, 70.44 APE8-rot-na 34.65 APE67-dihe-in -69.8, 5.09 -60.12, -39.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.0271 T790M,V948R None None XRAY 2.2 0.204 0.261 A 328.0 298.0 15 30 17 13 [[712, 970]] 1.0 8fv4 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4B P00533 702 1007 1210.0 No_ligand No_ligand Inactive DFGin 5.1269 16.3621 BLBtrans -126.57, 176.61 61.99, 14.29 -48.04, 140.93 155.83, 88.84 81.69, -24.77 out-out out 14.3774 Saltbr-out 14.4834 HRD-in -71.39, -59.22 91.02, -25.25 out-out-none SNCoon out-none ActLoopNT-out 6.6572 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 172.6 APE9-dihe-in -105.91, 119.23 APE8-dihe-in -74.97, 58.92 APE8-rot-na 28.96 APE67-dihe-in -73.69, -0.36 -43.23, -49.45 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.9349 APE9-dist-in 7.6683 T790M,V948R None None XRAY 2.2 0.204 0.261 B 328.0 303.0 3 30 27 3 [[712, 970]] 1.0 8fv4 TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8FV4 — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 2 50.0% 8FV4C
DFGin BLBtrans 2 50.0% 8FV4B
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 8FV4C P00533 702 1013 1210.0 ANP:1102 ATPlike Inactive DFGin 4.0815 13.5578 BLBplus -127.73, 168.23 73.07, 11.78 -61.24, 145.82 61.45, 98.91 81.41, -31.2 out-out out 13.7417 Saltbr-out 16.1154 HRD-in -67.13, -63.64 88.26, -13.01 out-out-out SNCooo out-out ActLoopNT-out 6.5839 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaao APE10-dihe-out -45.21, -49.43 APE9-dihe-in -74.91, 126.99 APE8-dihe-in -76.17, 58.7 APE8-rot-na 28.97 APE67-dihe-in -74.88, -4.9 -52.62, -40.92 APE12-dist-na 999.0 APE11-dist-na 16.2617 APE10-dist-na 12.2316 APE9-dist-out 8.1002 T790M,V948R None None XRAY 2.2 0.204 0.261 C 328.0 296.0 11 30 19 11 [[712, 970]] 1.0 8fv4 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4D P00533 701 1005 1210.0 YAA:1101 Type1.5_Back Inactive DFGin 4.3363 14.1928 BLBplus -131.61, 167.63 65.73, 30.81 -71.32, 133.31 54.39, 91.6 84.61, 0.99 out-out out 13.9441 Saltbr-out 12.4326 HRD-in -68.84, -58.76 79.63, -1.53 out-out-none SNCoon out-none ActLoopNT-out 7.0831 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 100.68 APE8-dihe-in -73.69, 77.18 APE8-rot-na 31.74 APE67-dihe-in -70.65, -4.38 -67.28, -33.85 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.8152 T790M,V948R None None XRAY 2.2 0.204 0.261 D 328.0 291.0 14 30 17 13 [[712, 970]] 1.0 8fv4 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4A P00533 701 1013 1210.0 ANP:1102 ATPlike Inactive DFGin 5.115 16.0834 BLBtrans -131.04, 178.71 63.39, 21.89 -65.77, 133.12 153.56, 67.25 81.77, -5.74 out-out out 13.9648 Saltbr-out 14.3656 HRD-in -75.29, -65.35 93.54, -10.41 out-out-out SNCooo out-out ActLoopNT-out 6.6138 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 123.22 APE8-dihe-in -79.99, 70.44 APE8-rot-na 34.65 APE67-dihe-in -69.8, 5.09 -60.12, -39.98 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.0271 T790M,V948R None None XRAY 2.2 0.204 0.261 A 328.0 298.0 15 30 17 13 [[712, 970]] 1.0 8fv4 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 8FV4B P00533 702 1007 1210.0 No_ligand No_ligand Inactive DFGin 5.1269 16.3621 BLBtrans -126.57, 176.61 61.99, 14.29 -48.04, 140.93 155.83, 88.84 81.69, -24.77 out-out out 14.3774 Saltbr-out 14.4834 HRD-in -71.39, -59.22 91.02, -25.25 out-out-none SNCoon out-none ActLoopNT-out 6.6572 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, 172.6 APE9-dihe-in -105.91, 119.23 APE8-dihe-in -74.97, 58.92 APE8-rot-na 28.96 APE67-dihe-in -73.69, -0.36 -43.23, -49.45 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.9349 APE9-dist-in 7.6683 T790M,V948R None None XRAY 2.2 0.204 0.261 B 328.0 303.0 3 30 27 3 [[712, 970]] 1.0 8fv4 Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 8FV4 — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name