PDB: 8DKS — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8DKSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8DKSA Q9NWZ3 165 459 460.0 SO9:501 Type1 Inactive DFGin 6.9825 14.0197 BLAminus -134.64, 178.03 63.45, 86.35 -110.27, 29.73 310.97, 98.17 -70.79, -35.85 in-out in 8.2912 Saltbr-out 4.4467 HRD-in -75.38, -48.79 72.8, 5.5 out-in-in SNCoii in-in ActLoopNT-in 2.9065 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.77, 162.36 APE9-dihe-na 128.07, -167.6 APE8-dihe-in -119.72, 111.55 APE8-rot-in 307.86 APE67-dihe-in -64.51, -15.13 -57.7, -32.23 APE12-dist-in 9.8577 APE11-dist-in 11.5245 APE10-dist-in 6.2214 APE9-dist-in 3.6652 None SEP346 SEP346 XRAY 2.45 0.215 0.267 A 460.0 283.0 12 30 23 7 [[183, 456]] 1.0 8dks TKL_IRAK4_HUMAN TKL 1.6e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8DKSB Q9NWZ3 164 459 460.0 SO9:501 Type1 Inactive DFGin 7.0195 14.2623 BLAminus -133.36, 172.32 69.94, 86.94 -110.0, 21.28 306.52, 104.01 -69.01, -36.15 in-out in 8.4475 Saltbr-out 4.2848 HRD-in -74.58, -51.41 77.38, 3.56 out-in-in SNCoii in-in ActLoopNT-in 2.6651 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.18, 157.32 APE9-dihe-na 125.46, -172.72 APE8-dihe-in -116.19, 115.21 APE8-rot-in 297.6 APE67-dihe-in -69.09, -18.07 -48.21, -41.4 APE12-dist-in 10.1058 APE11-dist-in 11.7004 APE10-dist-in 6.2871 APE9-dist-in 3.8575 None SEP346 SEP346 XRAY 2.45 0.215 0.267 B 460.0 278.0 18 30 24 6 [[183, 456]] 1.0 8dks TKL_IRAK4_HUMAN TKL 1.6e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8DKS — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8DKSA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8DKSA Q9NWZ3 165 459 460.0 SO9:501 Type1 Inactive DFGin 6.9825 14.0197 BLAminus -134.64, 178.03 63.45, 86.35 -110.27, 29.73 310.97, 98.17 -70.79, -35.85 in-out in 8.2912 Saltbr-out 4.4467 HRD-in -75.38, -48.79 72.8, 5.5 out-in-in SNCoii in-in ActLoopNT-in 2.9065 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -143.77, 162.36 APE9-dihe-na 128.07, -167.6 APE8-dihe-in -119.72, 111.55 APE8-rot-in 307.86 APE67-dihe-in -64.51, -15.13 -57.7, -32.23 APE12-dist-in 9.8577 APE11-dist-in 11.5245 APE10-dist-in 6.2214 APE9-dist-in 3.6652 None SEP346 SEP346 XRAY 2.45 0.215 0.267 A 460.0 283.0 12 30 23 7 [[183, 456]] 1.0 8dks Homo sapiens TKL_IRAK4_HUMAN TKL 1.6e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8DKSB Q9NWZ3 164 459 460.0 SO9:501 Type1 Inactive DFGin 7.0195 14.2623 BLAminus -133.36, 172.32 69.94, 86.94 -110.0, 21.28 306.52, 104.01 -69.01, -36.15 in-out in 8.4475 Saltbr-out 4.2848 HRD-in -74.58, -51.41 77.38, 3.56 out-in-in SNCoii in-in ActLoopNT-in 2.6651 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -135.18, 157.32 APE9-dihe-na 125.46, -172.72 APE8-dihe-in -116.19, 115.21 APE8-rot-in 297.6 APE67-dihe-in -69.09, -18.07 -48.21, -41.4 APE12-dist-in 10.1058 APE11-dist-in 11.7004 APE10-dist-in 6.2871 APE9-dist-in 3.8575 None SEP346 SEP346 XRAY 2.45 0.215 0.267 B 460.0 278.0 18 30 24 6 [[183, 456]] 1.0 8dks Homo sapiens TKL_IRAK4_HUMAN TKL 1.6e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8DKS — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name