PDB: 8C08 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8C08A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 8C08A O60674 537 810 1132.0 ATP:901 ATPlike Pseudo DFGin 6.5983 13.736 None -72.21, 176.69 -66.6, 164.57 -72.8, -15.2 349.18, 27.02 73.34, -163.25 in-na in 9.3998 Saltbr-na 999.0 HRD-in -80.72, -74.63 111.24, -16.83 na-out-out SNCaoo out-out ActLoopNT-out 9.4736 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -55.86, -37.52 APE9-dihe-out -72.05, -28.92 APE8-dihe-out -74.69, -10.21 APE8-rot-na 283.12 APE67-dihe-out -93.42, 18.23 -54.81, 139.34 APE12-dist-na 9.9203 APE11-dist-na 11.8594 APE10-dist-na 16.3524 APE9-dist-out 12.5304 W659A,W777A,F794H None None XRAY 2.2 0.267 0.259 A 289.0 270.0 4 24 24 0 [[545, 807], [849, 1125]] 2.0 8c08 TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C08B O60674 536 810 1132.0 ATP:901 ATPlike Pseudo DFGin 5.6459 13.5394 None -63.04, -178.12 -72.48, 164.14 -59.19, -39.37 337.51, 34.58 89.58, -173.09 out-na out 12.1784 Saltbr-na 999.0 HRD-in -76.08, -63.96 89.49, 0.26 na-out-out SNCaoo out-out ActLoopNT-out 8.7296 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.09, -36.29 APE9-dihe-out -67.21, -14.45 APE8-dihe-out -97.09, 0.9 APE8-rot-na 279.42 APE67-dihe-out -95.31, 21.21 -63.75, 135.54 APE12-dist-na 10.8478 APE11-dist-na 11.8372 APE10-dist-na 16.5999 APE9-dist-out 12.658 W659A,W777A,F794H None None XRAY 2.2 0.267 0.259 B 289.0 269.0 6 24 24 0 [[545, 807], [849, 1125]] 2.0 8c08 TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

PDB: 8C08 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 8C08A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 8C08A O60674 537 810 1132.0 ATP:901 ATPlike Pseudo DFGin 6.5983 13.736 None -72.21, 176.69 -66.6, 164.57 -72.8, -15.2 349.18, 27.02 73.34, -163.25 in-na in 9.3998 Saltbr-na 999.0 HRD-in -80.72, -74.63 111.24, -16.83 na-out-out SNCaoo out-out ActLoopNT-out 9.4736 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -55.86, -37.52 APE9-dihe-out -72.05, -28.92 APE8-dihe-out -74.69, -10.21 APE8-rot-na 283.12 APE67-dihe-out -93.42, 18.23 -54.81, 139.34 APE12-dist-na 9.9203 APE11-dist-na 11.8594 APE10-dist-na 16.3524 APE9-dist-out 12.5304 W659A,W777A,F794H None None XRAY 2.2 0.267 0.259 A 289.0 270.0 4 24 24 0 [[545, 807], [849, 1125]] 2.0 8c08 Homo sapiens TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 8C08B O60674 536 810 1132.0 ATP:901 ATPlike Pseudo DFGin 5.6459 13.5394 None -63.04, -178.12 -72.48, 164.14 -59.19, -39.37 337.51, 34.58 89.58, -173.09 out-na out 12.1784 Saltbr-na 999.0 HRD-in -76.08, -63.96 89.49, 0.26 na-out-out SNCaoo out-out ActLoopNT-out 8.7296 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -65.09, -36.29 APE9-dihe-out -67.21, -14.45 APE8-dihe-out -97.09, 0.9 APE8-rot-na 279.42 APE67-dihe-out -95.31, 21.21 -63.75, 135.54 APE12-dist-na 10.8478 APE11-dist-na 11.8372 APE10-dist-na 16.5999 APE9-dist-out 12.658 W659A,W777A,F794H None None XRAY 2.2 0.267 0.259 B 289.0 269.0 6 24 24 0 [[545, 807], [849, 1125]] 2.0 8c08 Homo sapiens TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

PDB: 8C08 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name