PDB: 8BX9 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8BX9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8BX9A O60674 840 1132 1132.0 S59:61201 Type1 Inactive DFGin 6.2823 13.3135 ABAminus -115.66, -15.46 -143.67, 143.69 -132.35, 26.34 296.6, 90.45 -62.57, -27.31 in-in in 8.6932 Saltbr-in 2.7077 HRD-in -72.71, -45.4 77.34, -11.34 in-in-in SNCiii in-in ActLoopNT-in 2.8118 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.37, 138.38 APE9-dihe-in -118.57, 132.52 APE8-dihe-in -81.71, 72.52 APE8-rot-na 30.52 APE67-dihe-in -77.4, -1.6 -57.61, -31.37 APE12-dist-na 10.3478 APE11-dist-na 9.3824 APE10-dist-na 10.3305 APE9-dist-in 7.3391 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.4 0.193 0.223 A 316.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 8bx9 TYR_JAK2-2_HUMAN TYR 3.2e-87 298.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BX9B O60674 840 1132 1132.0 S59:61201 Type1 Inactive DFGin 6.2907 13.3324 ABAminus -114.72, -14.51 -143.68, 140.34 -129.13, 28.22 298.96, 84.54 -63.48, -25.1 in-in in 8.6656 Saltbr-in 2.6439 HRD-in -70.33, -47.05 74.41, -10.04 in-in-in SNCiii in-in ActLoopNT-in 2.7935 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.07, 136.0 APE9-dihe-in -119.91, 128.99 APE8-dihe-in -80.21, 75.11 APE8-rot-na 32.85 APE67-dihe-in -76.92, -1.3 -60.27, -31.85 APE12-dist-na 10.4676 APE11-dist-na 9.724 APE10-dist-na 10.1473 APE9-dist-in 7.2853 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.4 0.193 0.223 B 316.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 8bx9 TYR_JAK2-2_HUMAN TYR 3.2e-87 298.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 8BX9 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 8BX9A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 8BX9A O60674 840 1132 1132.0 S59:61201 Type1 Inactive DFGin 6.2823 13.3135 ABAminus -115.66, -15.46 -143.67, 143.69 -132.35, 26.34 296.6, 90.45 -62.57, -27.31 in-in in 8.6932 Saltbr-in 2.7077 HRD-in -72.71, -45.4 77.34, -11.34 in-in-in SNCiii in-in ActLoopNT-in 2.8118 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -75.37, 138.38 APE9-dihe-in -118.57, 132.52 APE8-dihe-in -81.71, 72.52 APE8-rot-na 30.52 APE67-dihe-in -77.4, -1.6 -57.61, -31.37 APE12-dist-na 10.3478 APE11-dist-na 9.3824 APE10-dist-na 10.3305 APE9-dist-in 7.3391 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.4 0.193 0.223 A 316.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 8bx9 Homo sapiens TYR_JAK2-2_HUMAN TYR 3.2e-87 298.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 8BX9B O60674 840 1132 1132.0 S59:61201 Type1 Inactive DFGin 6.2907 13.3324 ABAminus -114.72, -14.51 -143.68, 140.34 -129.13, 28.22 298.96, 84.54 -63.48, -25.1 in-in in 8.6656 Saltbr-in 2.6439 HRD-in -70.33, -47.05 74.41, -10.04 in-in-in SNCiii in-in ActLoopNT-in 2.7935 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -82.07, 136.0 APE9-dihe-in -119.91, 128.99 APE8-dihe-in -80.21, 75.11 APE8-rot-na 32.85 APE67-dihe-in -76.92, -1.3 -60.27, -31.85 APE12-dist-na 10.4676 APE11-dist-na 9.724 APE10-dist-na 10.1473 APE9-dist-in 7.2853 None PTR1007,PTR1008 PTR1007,PTR1008 XRAY 1.4 0.193 0.223 B 316.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 8bx9 Homo sapiens TYR_JAK2-2_HUMAN TYR 3.2e-87 298.1 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 8BX9 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name