PDB: 8BR7 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8BR7BBB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8BR7AAA Q9NWZ3 165 458 460.0 R6R:501 Type1 Inactive DFGin 6.7483 13.7843 BLAminus -121.68, 175.13 64.52, 68.33 -88.96, 4.22 313.41, 97.24 -60.18, 142.14 in-out in 8.2357 Saltbr-out 7.7831 HRD-in -69.56, -54.74 85.52, -4.41 out-in-in SNCoii in-in ActLoopNT-in 2.938 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.26, 163.97 APE9-dihe-na 117.6, -170.85 APE8-dihe-in -114.4, 114.65 APE8-rot-in 314.25 APE67-dihe-in -62.57, -14.8 -45.12, -53.09 APE12-dist-in 9.6098 APE11-dist-in 11.5218 APE10-dist-in 6.0807 APE9-dist-in 3.6881 K400A,E401A,E402A TPO345,SEP346 TPO345,SEP346 XRAY 2.119 0.241 0.288 AAA 298.0 273.0 21 30 24 6 [[183, 456]] 1.0 8br7 TKL_IRAK4_HUMAN TKL 1.3e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR7BBB Q9NWZ3 165 458 460.0 R6R:501 Type1 Inactive DFGin 6.7251 14.0843 BLAminus -127.23, 169.57 70.93, 84.26 -111.93, 23.51 310.86, 94.87 -67.5, -27.24 in-out in 9.0787 Saltbr-out 4.6695 HRD-in -74.15, -52.75 85.58, -3.83 out-in-in SNCoii in-in ActLoopNT-in 2.7055 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.6, 148.06 APE9-dihe-na 139.81, -171.92 APE8-dihe-in -112.09, 123.4 APE8-rot-in 327.06 APE67-dihe-in -62.8, -13.81 -52.63, -52.65 APE12-dist-in 10.0265 APE11-dist-in 11.8292 APE10-dist-in 6.6234 APE9-dist-in 3.9928 K400A,E401A,E402A TPO345,SEP346 TPO345,SEP346 XRAY 2.119 0.241 0.288 BBB 298.0 278.0 16 30 25 5 [[183, 456]] 1.0 8br7 TKL_IRAK4_HUMAN TKL 1.3e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8BR7 — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8BR7BBB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8BR7AAA Q9NWZ3 165 458 460.0 R6R:501 Type1 Inactive DFGin 6.7483 13.7843 BLAminus -121.68, 175.13 64.52, 68.33 -88.96, 4.22 313.41, 97.24 -60.18, 142.14 in-out in 8.2357 Saltbr-out 7.7831 HRD-in -69.56, -54.74 85.52, -4.41 out-in-in SNCoii in-in ActLoopNT-in 2.938 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -127.26, 163.97 APE9-dihe-na 117.6, -170.85 APE8-dihe-in -114.4, 114.65 APE8-rot-in 314.25 APE67-dihe-in -62.57, -14.8 -45.12, -53.09 APE12-dist-in 9.6098 APE11-dist-in 11.5218 APE10-dist-in 6.0807 APE9-dist-in 3.6881 K400A,E401A,E402A TPO345,SEP346 TPO345,SEP346 XRAY 2.119 0.241 0.288 AAA 298.0 273.0 21 30 24 6 [[183, 456]] 1.0 8br7 Homo sapiens TKL_IRAK4_HUMAN TKL 1.3e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8BR7BBB Q9NWZ3 165 458 460.0 R6R:501 Type1 Inactive DFGin 6.7251 14.0843 BLAminus -127.23, 169.57 70.93, 84.26 -111.93, 23.51 310.86, 94.87 -67.5, -27.24 in-out in 9.0787 Saltbr-out 4.6695 HRD-in -74.15, -52.75 85.58, -3.83 out-in-in SNCoii in-in ActLoopNT-in 2.7055 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -146.6, 148.06 APE9-dihe-na 139.81, -171.92 APE8-dihe-in -112.09, 123.4 APE8-rot-in 327.06 APE67-dihe-in -62.8, -13.81 -52.63, -52.65 APE12-dist-in 10.0265 APE11-dist-in 11.8292 APE10-dist-in 6.6234 APE9-dist-in 3.9928 K400A,E401A,E402A TPO345,SEP346 TPO345,SEP346 XRAY 2.119 0.241 0.288 BBB 298.0 278.0 16 30 25 5 [[183, 456]] 1.0 8br7 Homo sapiens TKL_IRAK4_HUMAN TKL 1.3e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8BR7 — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name