PDB: 8ATB — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8ATBBBB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8ATBAAA Q9NWZ3 165 459 460.0 O0H:501 Type1 Inactive DFGin 6.9325 14.0449 BLAminus -121.47, 173.79 68.09, 102.5 -125.51, 19.89 306.28, 88.96 -63.31, -35.55 in-out in 9.0143 Saltbr-out 4.7306 HRD-in -76.64, -56.17 81.36, 1.11 out-in-in SNCoii in-in ActLoopNT-in 2.7117 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.25, 147.68 APE9-dihe-na 138.07, -176.27 APE8-dihe-in -102.25, 110.92 APE8-rot-in 311.13 APE67-dihe-in -58.31, -27.03 -61.07, -35.05 APE12-dist-in 10.3429 APE11-dist-in 11.7734 APE10-dist-in 6.4836 APE9-dist-in 4.0423 K400A,E401A,E402A TPO345,SEP346 CSO240,CSO289,TPO345,SEP346 XRAY 2.35 0.214 0.26 AAA 298.0 280.0 15 30 22 8 [[183, 456]] 1.0 8atb TKL_IRAK4_HUMAN TKL 1.3e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8ATBBBB Q9NWZ3 165 459 460.0 O0H:501 Type1 Inactive DFGin 7.2148 13.7854 BLAminus -128.79, 170.66 65.65, 84.73 -111.53, 16.19 311.14, 85.88 -77.86, -13.48 in-out in 8.5669 Saltbr-out 7.2399 HRD-in -72.73, -56.78 83.28, 0.6 out-in-in SNCoii in-in ActLoopNT-in 2.6798 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.97, 161.24 APE9-dihe-na 134.69, -177.34 APE8-dihe-in -106.53, 101.49 APE8-rot-in 315.43 APE67-dihe-in -62.03, -21.88 -37.43, -49.3 APE12-dist-in 10.6974 APE11-dist-in 12.0305 APE10-dist-in 7.3801 APE9-dist-in 4.3329 K400A,E401A,E402A TPO345,SEP346 CSO240,CSO289,TPO345,SEP346 XRAY 2.35 0.214 0.26 BBB 298.0 282.0 13 30 24 6 [[183, 456]] 1.0 8atb TKL_IRAK4_HUMAN TKL 1.3e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8ATB — TKL IRAK4_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 2 100.0% 8ATBBBB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TKL IRAK4 IRAK4_HUMAN 8ATBAAA Q9NWZ3 165 459 460.0 O0H:501 Type1 Inactive DFGin 6.9325 14.0449 BLAminus -121.47, 173.79 68.09, 102.5 -125.51, 19.89 306.28, 88.96 -63.31, -35.55 in-out in 9.0143 Saltbr-out 4.7306 HRD-in -76.64, -56.17 81.36, 1.11 out-in-in SNCoii in-in ActLoopNT-in 2.7117 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -133.25, 147.68 APE9-dihe-na 138.07, -176.27 APE8-dihe-in -102.25, 110.92 APE8-rot-in 311.13 APE67-dihe-in -58.31, -27.03 -61.07, -35.05 APE12-dist-in 10.3429 APE11-dist-in 11.7734 APE10-dist-in 6.4836 APE9-dist-in 4.0423 K400A,E401A,E402A TPO345,SEP346 CSO240,CSO289,TPO345,SEP346 XRAY 2.35 0.214 0.26 AAA 298.0 280.0 15 30 22 8 [[183, 456]] 1.0 8atb Homo sapiens TKL_IRAK4_HUMAN TKL 1.3e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4
TKL IRAK4 IRAK4_HUMAN 8ATBBBB Q9NWZ3 165 459 460.0 O0H:501 Type1 Inactive DFGin 7.2148 13.7854 BLAminus -128.79, 170.66 65.65, 84.73 -111.53, 16.19 311.14, 85.88 -77.86, -13.48 in-out in 8.5669 Saltbr-out 7.2399 HRD-in -72.73, -56.78 83.28, 0.6 out-in-in SNCoii in-in ActLoopNT-in 2.6798 ActLoopCT-in nonTYR APEdihe_aaiii APEdist_iiii APE10-dihe-na -125.97, 161.24 APE9-dihe-na 134.69, -177.34 APE8-dihe-in -106.53, 101.49 APE8-rot-in 315.43 APE67-dihe-in -62.03, -21.88 -37.43, -49.3 APE12-dist-in 10.6974 APE11-dist-in 12.0305 APE10-dist-in 7.3801 APE9-dist-in 4.3329 K400A,E401A,E402A TPO345,SEP346 CSO240,CSO289,TPO345,SEP346 XRAY 2.35 0.214 0.26 BBB 298.0 282.0 13 30 24 6 [[183, 456]] 1.0 8atb Homo sapiens TKL_IRAK4_HUMAN TKL 1.3e-83 286.6 5.0 266.0 262.0 328 329 330 332 334 213 233 237 308 310 309 311.0 369 358 353 352 351 350 349 348 347 263 Interleukin-1 receptor-associated kinase 4

PDB: 8ATB — TKL IRAK4_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name