PDB: 7UYV — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7UYVB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein
TYR JAK3-2 JAK3_HUMAN 7UYVA 2.15 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7UYVB 2.15 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7UYVC 2.15 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao OV5 Type1 812 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3
TYR JAK3-2 JAK3_HUMAN 7UYVD 2.15 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3

PDB: 7UYV — TYR JAK3_HUMAN

Total number of chains: 4
Active chains: 2
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLAminus 4 100.0% 7UYVB

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism
TYR JAK3-2 JAK3_HUMAN 7UYVA 2.15 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 7UYVB 2.15 Active DFGin‑BLAminus in-in in-in TYR APEdihe_iiiai APEdist_aaai OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 7UYVC 2.15 Inactive DFGin‑BLAminus in-in in-out TYR APEdihe_iiiai APEdist_aaao OV5 Type1 812 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens
TYR JAK3-2 JAK3_HUMAN 7UYVD 2.15 None DFGin‑BLAminus in-in in-none TYR APEdihe_nniai APEdist_aaai OV5 Type1 814 - 1100 0 PTR980,PTR981 None Tyrosine-protein kinase JAK3 Homo sapiens

PDB: 7UYV — TYR JAK3_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

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Family Gene UniprotID PDB Resolution Activity Spatial-Dihedral Chelix-SaltBridge ActLoopNT-ActLoopCT APEtype APEdihe APEdist Ligand Ligand Type Residues in structure Unresolved residues in A-loop Phosphorylation Mutation Protein Organism