| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OTHER | PINK1 | PINK1_PEDHC | 7T4MA | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4567 | 15.3433 | BLAminus | -127.4, -170.86 | 58.97, 63.02 | -87.19, 20.85 | 281.34, 75.45 | -64.84, -21.34 | in-out | in | 8.1944 | Saltbr-out | 3.885 | HRD-in | -68.66, -42.56 | 64.85, 4.3 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6865 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.59, -140.69 | APE9-dihe-na | -106.62, -106.93 | APE8-dihe-in | -68.31, 139.19 | APE8-rot-na | 59.41 | APE67-dihe-in | -67.76, -42.21 | -82.79, -14.93 | APE12-dist-in | 7.7682 | APE11-dist-in | 10.1876 | APE10-dist-in | 5.7017 | APE9-dist-in | 3.8117 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | A | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MB | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4458 | 15.1586 | BLAminus | -124.66, -170.75 | 57.76, 62.9 | -85.07, 17.46 | 283.69, 83.5 | -66.21, -19.41 | in-in | in | 8.1446 | Saltbr-in | 2.9807 | HRD-in | -66.82, -42.5 | 62.63, 5.38 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6814 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.09, -157.06 | APE9-dihe-na | -101.87, -102.82 | APE8-dihe-in | -69.46, 135.78 | APE8-rot-na | 61.3 | APE67-dihe-in | -67.7, -41.91 | -79.71, -16.62 | APE12-dist-in | 7.6671 | APE11-dist-in | 10.2472 | APE10-dist-in | 5.8331 | APE9-dist-in | 3.7106 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | B | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MC | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4559 | 15.3428 | BLAminus | -127.47, -170.9 | 58.97, 63.06 | -87.21, 20.89 | 281.25, 75.56 | -64.84, -21.3 | in-out | in | 8.194 | Saltbr-out | 3.8854 | HRD-in | -68.73, -42.51 | 64.89, 4.27 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6868 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.58, -140.72 | APE9-dihe-na | -106.57, -107.0 | APE8-dihe-in | -68.26, 139.18 | APE8-rot-na | 59.39 | APE67-dihe-in | -67.66, -42.32 | -82.76, -14.96 | APE12-dist-in | 7.7688 | APE11-dist-in | 10.1871 | APE10-dist-in | 5.7016 | APE9-dist-in | 3.8105 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | C | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MD | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4453 | 15.1586 | BLAminus | -124.71, -170.76 | 57.78, 62.93 | -85.11, 17.45 | 283.65, 83.55 | -66.22, -19.41 | in-in | in | 8.1433 | Saltbr-in | 2.9813 | HRD-in | -66.81, -42.58 | 62.67, 5.34 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6811 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.07, -157.03 | APE9-dihe-na | -101.91, -102.76 | APE8-dihe-in | -69.48, 135.84 | APE8-rot-na | 61.21 | APE67-dihe-in | -67.68, -41.9 | -79.71, -16.67 | APE12-dist-in | 7.6656 | APE11-dist-in | 10.2463 | APE10-dist-in | 5.8322 | APE9-dist-in | 3.7105 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | D | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4ME | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4552 | 15.3425 | BLAminus | -127.47, -170.84 | 58.9, 63.05 | -87.16, 20.84 | 281.31, 75.5 | -64.82, -21.31 | in-out | in | 8.1941 | Saltbr-out | 3.8848 | HRD-in | -68.66, -42.58 | 64.89, 4.28 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6861 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.56, -140.66 | APE9-dihe-na | -106.59, -106.95 | APE8-dihe-in | -68.27, 139.21 | APE8-rot-na | 59.41 | APE67-dihe-in | -67.7, -42.34 | -82.79, -14.94 | APE12-dist-in | 7.7686 | APE11-dist-in | 10.1868 | APE10-dist-in | 5.7011 | APE9-dist-in | 3.8117 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | E | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MF | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4457 | 15.1575 | BLAminus | -124.72, -170.76 | 57.86, 62.86 | -85.09, 17.45 | 283.71, 83.57 | -66.15, -19.49 | in-in | in | 8.1434 | Saltbr-in | 2.9813 | HRD-in | -66.83, -42.48 | 62.6, 5.43 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6813 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.08, -157.09 | APE9-dihe-na | -101.83, -102.79 | APE8-dihe-in | -69.48, 135.79 | APE8-rot-na | 61.21 | APE67-dihe-in | -67.63, -41.93 | -79.68, -16.69 | APE12-dist-in | 7.6662 | APE11-dist-in | 10.2467 | APE10-dist-in | 5.833 | APE9-dist-in | 3.7105 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | F | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MG | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4562 | 15.3436 | BLAminus | -127.44, -170.88 | 58.97, 63.08 | -87.21, 20.88 | 281.29, 75.51 | -64.84, -21.36 | in-out | in | 8.1943 | Saltbr-out | 3.8848 | HRD-in | -68.75, -42.55 | 64.93, 4.23 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6864 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.58, -140.73 | APE9-dihe-na | -106.61, -106.93 | APE8-dihe-in | -68.3, 139.23 | APE8-rot-na | 59.38 | APE67-dihe-in | -67.77, -42.24 | -82.83, -14.9 | APE12-dist-in | 7.7686 | APE11-dist-in | 10.1867 | APE10-dist-in | 5.7012 | APE9-dist-in | 3.8113 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | G | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MH | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4454 | 15.1585 | BLAminus | -124.65, -170.74 | 57.77, 62.9 | -85.07, 17.42 | 283.68, 83.49 | -66.18, -19.44 | in-in | in | 8.144 | Saltbr-in | 2.9811 | HRD-in | -66.85, -42.45 | 62.6, 5.35 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6817 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.02, -157.1 | APE9-dihe-na | -101.92, -102.83 | APE8-dihe-in | -69.44, 135.8 | APE8-rot-na | 61.22 | APE67-dihe-in | -67.66, -41.95 | -79.67, -16.64 | APE12-dist-in | 7.6661 | APE11-dist-in | 10.2467 | APE10-dist-in | 5.8333 | APE9-dist-in | 3.7111 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | H | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MI | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4556 | 15.3425 | BLAminus | -127.45, -170.82 | 58.99, 63.0 | -87.25, 20.98 | 281.25, 75.5 | -64.87, -21.33 | in-out | in | 8.1943 | Saltbr-out | 3.884 | HRD-in | -68.66, -42.61 | 64.96, 4.2 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6861 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.59, -140.7 | APE9-dihe-na | -106.56, -106.93 | APE8-dihe-in | -68.32, 139.25 | APE8-rot-na | 59.38 | APE67-dihe-in | -67.7, -42.28 | -82.79, -14.99 | APE12-dist-in | 7.7684 | APE11-dist-in | 10.1871 | APE10-dist-in | 5.7019 | APE9-dist-in | 3.8113 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | I | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MJ | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4459 | 15.1587 | BLAminus | -124.74, -170.75 | 57.78, 62.94 | -85.14, 17.48 | 283.67, 83.57 | -66.2, -19.36 | in-in | in | 8.1438 | Saltbr-in | 2.9814 | HRD-in | -66.85, -42.5 | 62.69, 5.31 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6813 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.09, -157.04 | APE9-dihe-na | -101.89, -102.82 | APE8-dihe-in | -69.44, 135.89 | APE8-rot-na | 61.26 | APE67-dihe-in | -67.65, -41.92 | -79.75, -16.69 | APE12-dist-in | 7.6662 | APE11-dist-in | 10.247 | APE10-dist-in | 5.8327 | APE9-dist-in | 3.7102 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | J | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MK | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4561 | 15.3431 | BLAminus | -127.45, -170.84 | 58.91, 63.06 | -87.21, 20.87 | 281.29, 75.54 | -64.8, -21.37 | in-out | in | 8.1943 | Saltbr-out | 3.8848 | HRD-in | -68.66, -42.56 | 64.86, 4.32 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6868 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.61, -140.66 | APE9-dihe-na | -106.66, -106.92 | APE8-dihe-in | -68.31, 139.18 | APE8-rot-na | 59.35 | APE67-dihe-in | -67.65, -42.32 | -82.71, -15.04 | APE12-dist-in | 7.7691 | APE11-dist-in | 10.1874 | APE10-dist-in | 5.7019 | APE9-dist-in | 3.8114 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | K | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4ML | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4459 | 15.1581 | BLAminus | -124.68, -170.8 | 57.84, 62.88 | -85.03, 17.42 | 283.74, 83.54 | -66.23, -19.4 | in-in | in | 8.1437 | Saltbr-in | 2.9816 | HRD-in | -66.77, -42.55 | 62.69, 5.3 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6806 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.08, -157.11 | APE9-dihe-na | -101.89, -102.77 | APE8-dihe-in | -69.47, 135.83 | APE8-rot-na | 61.25 | APE67-dihe-in | -67.72, -41.88 | -79.65, -16.7 | APE12-dist-in | 7.6665 | APE11-dist-in | 10.2469 | APE10-dist-in | 5.8336 | APE9-dist-in | 3.7104 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | L | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OTHER | PINK1 | PINK1_PEDHC | 7T4MA | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4567 | 15.3433 | BLAminus | -127.4, -170.86 | 58.97, 63.02 | -87.19, 20.85 | 281.34, 75.45 | -64.84, -21.34 | in-out | in | 8.1944 | Saltbr-out | 3.885 | HRD-in | -68.66, -42.56 | 64.85, 4.3 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6865 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.59, -140.69 | APE9-dihe-na | -106.62, -106.93 | APE8-dihe-in | -68.31, 139.19 | APE8-rot-na | 59.41 | APE67-dihe-in | -67.76, -42.21 | -82.79, -14.93 | APE12-dist-in | 7.7682 | APE11-dist-in | 10.1876 | APE10-dist-in | 5.7017 | APE9-dist-in | 3.8117 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | A | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MB | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4458 | 15.1586 | BLAminus | -124.66, -170.75 | 57.76, 62.9 | -85.07, 17.46 | 283.69, 83.5 | -66.21, -19.41 | in-in | in | 8.1446 | Saltbr-in | 2.9807 | HRD-in | -66.82, -42.5 | 62.63, 5.38 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6814 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.09, -157.06 | APE9-dihe-na | -101.87, -102.82 | APE8-dihe-in | -69.46, 135.78 | APE8-rot-na | 61.3 | APE67-dihe-in | -67.7, -41.91 | -79.71, -16.62 | APE12-dist-in | 7.6671 | APE11-dist-in | 10.2472 | APE10-dist-in | 5.8331 | APE9-dist-in | 3.7106 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | B | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MC | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4559 | 15.3428 | BLAminus | -127.47, -170.9 | 58.97, 63.06 | -87.21, 20.89 | 281.25, 75.56 | -64.84, -21.3 | in-out | in | 8.194 | Saltbr-out | 3.8854 | HRD-in | -68.73, -42.51 | 64.89, 4.27 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6868 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.58, -140.72 | APE9-dihe-na | -106.57, -107.0 | APE8-dihe-in | -68.26, 139.18 | APE8-rot-na | 59.39 | APE67-dihe-in | -67.66, -42.32 | -82.76, -14.96 | APE12-dist-in | 7.7688 | APE11-dist-in | 10.1871 | APE10-dist-in | 5.7016 | APE9-dist-in | 3.8105 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | C | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MD | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4453 | 15.1586 | BLAminus | -124.71, -170.76 | 57.78, 62.93 | -85.11, 17.45 | 283.65, 83.55 | -66.22, -19.41 | in-in | in | 8.1433 | Saltbr-in | 2.9813 | HRD-in | -66.81, -42.58 | 62.67, 5.34 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6811 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.07, -157.03 | APE9-dihe-na | -101.91, -102.76 | APE8-dihe-in | -69.48, 135.84 | APE8-rot-na | 61.21 | APE67-dihe-in | -67.68, -41.9 | -79.71, -16.67 | APE12-dist-in | 7.6656 | APE11-dist-in | 10.2463 | APE10-dist-in | 5.8322 | APE9-dist-in | 3.7105 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | D | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4ME | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4552 | 15.3425 | BLAminus | -127.47, -170.84 | 58.9, 63.05 | -87.16, 20.84 | 281.31, 75.5 | -64.82, -21.31 | in-out | in | 8.1941 | Saltbr-out | 3.8848 | HRD-in | -68.66, -42.58 | 64.89, 4.28 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6861 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.56, -140.66 | APE9-dihe-na | -106.59, -106.95 | APE8-dihe-in | -68.27, 139.21 | APE8-rot-na | 59.41 | APE67-dihe-in | -67.7, -42.34 | -82.79, -14.94 | APE12-dist-in | 7.7686 | APE11-dist-in | 10.1868 | APE10-dist-in | 5.7011 | APE9-dist-in | 3.8117 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | E | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MF | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4457 | 15.1575 | BLAminus | -124.72, -170.76 | 57.86, 62.86 | -85.09, 17.45 | 283.71, 83.57 | -66.15, -19.49 | in-in | in | 8.1434 | Saltbr-in | 2.9813 | HRD-in | -66.83, -42.48 | 62.6, 5.43 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6813 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.08, -157.09 | APE9-dihe-na | -101.83, -102.79 | APE8-dihe-in | -69.48, 135.79 | APE8-rot-na | 61.21 | APE67-dihe-in | -67.63, -41.93 | -79.68, -16.69 | APE12-dist-in | 7.6662 | APE11-dist-in | 10.2467 | APE10-dist-in | 5.833 | APE9-dist-in | 3.7105 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | F | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MG | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4562 | 15.3436 | BLAminus | -127.44, -170.88 | 58.97, 63.08 | -87.21, 20.88 | 281.29, 75.51 | -64.84, -21.36 | in-out | in | 8.1943 | Saltbr-out | 3.8848 | HRD-in | -68.75, -42.55 | 64.93, 4.23 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6864 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.58, -140.73 | APE9-dihe-na | -106.61, -106.93 | APE8-dihe-in | -68.3, 139.23 | APE8-rot-na | 59.38 | APE67-dihe-in | -67.77, -42.24 | -82.83, -14.9 | APE12-dist-in | 7.7686 | APE11-dist-in | 10.1867 | APE10-dist-in | 5.7012 | APE9-dist-in | 3.8113 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | G | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MH | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4454 | 15.1585 | BLAminus | -124.65, -170.74 | 57.77, 62.9 | -85.07, 17.42 | 283.68, 83.49 | -66.18, -19.44 | in-in | in | 8.144 | Saltbr-in | 2.9811 | HRD-in | -66.85, -42.45 | 62.6, 5.35 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6817 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.02, -157.1 | APE9-dihe-na | -101.92, -102.83 | APE8-dihe-in | -69.44, 135.8 | APE8-rot-na | 61.22 | APE67-dihe-in | -67.66, -41.95 | -79.67, -16.64 | APE12-dist-in | 7.6661 | APE11-dist-in | 10.2467 | APE10-dist-in | 5.8333 | APE9-dist-in | 3.7111 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | H | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MI | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4556 | 15.3425 | BLAminus | -127.45, -170.82 | 58.99, 63.0 | -87.25, 20.98 | 281.25, 75.5 | -64.87, -21.33 | in-out | in | 8.1943 | Saltbr-out | 3.884 | HRD-in | -68.66, -42.61 | 64.96, 4.2 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6861 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.59, -140.7 | APE9-dihe-na | -106.56, -106.93 | APE8-dihe-in | -68.32, 139.25 | APE8-rot-na | 59.38 | APE67-dihe-in | -67.7, -42.28 | -82.79, -14.99 | APE12-dist-in | 7.7684 | APE11-dist-in | 10.1871 | APE10-dist-in | 5.7019 | APE9-dist-in | 3.8113 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | I | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MJ | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4459 | 15.1587 | BLAminus | -124.74, -170.75 | 57.78, 62.94 | -85.14, 17.48 | 283.67, 83.57 | -66.2, -19.36 | in-in | in | 8.1438 | Saltbr-in | 2.9814 | HRD-in | -66.85, -42.5 | 62.69, 5.31 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6813 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.09, -157.04 | APE9-dihe-na | -101.89, -102.82 | APE8-dihe-in | -69.44, 135.89 | APE8-rot-na | 61.26 | APE67-dihe-in | -67.65, -41.92 | -79.75, -16.69 | APE12-dist-in | 7.6662 | APE11-dist-in | 10.247 | APE10-dist-in | 5.8327 | APE9-dist-in | 3.7102 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | J | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4MK | E0W1I1 | 116 | 574 | 575.0 | No_ligand | No_ligand | Inactive | DFGin | 9.4561 | 15.3431 | BLAminus | -127.45, -170.84 | 58.91, 63.06 | -87.21, 20.87 | 281.29, 75.54 | -64.8, -21.37 | in-out | in | 8.1943 | Saltbr-out | 3.8848 | HRD-in | -68.66, -42.56 | 64.86, 4.32 | out-in-in | SNCoii | in-in | ActLoopNT-in | 2.6868 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 153.61, -140.66 | APE9-dihe-na | -106.66, -106.92 | APE8-dihe-in | -68.31, 139.18 | APE8-rot-na | 59.35 | APE67-dihe-in | -67.65, -42.32 | -82.71, -15.04 | APE12-dist-in | 7.7691 | APE11-dist-in | 10.1874 | APE10-dist-in | 5.7019 | APE9-dist-in | 3.8114 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | K | 463.0 | 408.0 | 20 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |
| OTHER | PINK1 | PINK1_PEDHC | 7T4ML | E0W1I1 | 120 | 574 | 575.0 | No_ligand | No_ligand | Active | DFGin | 9.4459 | 15.1581 | BLAminus | -124.68, -170.8 | 57.84, 62.88 | -85.03, 17.42 | 283.74, 83.54 | -66.23, -19.4 | in-in | in | 8.1437 | Saltbr-in | 2.9816 | HRD-in | -66.77, -42.55 | 62.69, 5.3 | in-in-in | SNCiii | in-in | ActLoopNT-in | 2.6806 | ActLoopCT-in | nonTYR | APEdihe_aaiai | APEdist_iiii | APE10-dihe-na | 138.08, -157.11 | APE9-dihe-na | -101.89, -102.77 | APE8-dihe-in | -69.47, 135.83 | APE8-rot-na | 61.25 | APE67-dihe-in | -67.72, -41.88 | -79.65, -16.7 | APE12-dist-in | 7.6665 | APE11-dist-in | 10.2469 | APE10-dist-in | 5.8336 | APE9-dist-in | 3.7104 | D357A | None | None | EM | 2.48 | 999.0 | 999.0 | L | 463.0 | 401.0 | 22 | 34 | 34 | 0 | [[64, 514]] | 1.0 | 7t4m | Pediculus humanus | OTHER_PINK1_PEDHC | PINK1 | 1.6e-85 | 293.1 | 4.0 | 367.0 | 364.0 | 356 | 357 | 358 | 360 | 362 | 193 | 214 | 218 | 331 | 333 | 332 | 334.0 | 408 | 390 | 385 | 384 | 383 | 382 | 381 | 380 | 379 | 291 | Serine/threonine-protein kinase Pink1, mitochondrial |