PDB: 7T0P — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 7T0PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 7T0PA O60674 536 808 1132.0 E3W:901 Type1 Pseudo DFGin 5.5356 13.4525 None -71.36, 169.62 -64.37, 154.19 -64.4, -34.91 335.03, 35.41 82.73, -164.25 out-na out 11.6251 Saltbr-na 999.0 HRD-in -78.49, -60.16 92.47, -7.36 na-out-out SNCaoo out-out ActLoopNT-out 9.4113 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -60.7, -41.68 APE9-dihe-out -61.62, -27.73 APE8-dihe-out -89.13, 13.42 APE8-rot-na 292.46 APE67-dihe-out -104.69, 27.09 -67.15, 136.9 APE12-dist-na 10.1283 APE11-dist-na 11.4772 APE10-dist-na 16.1721 APE9-dist-out 12.8246 W659A,W777A,F794H None None XRAY 2.04 0.197 0.247 A 289.0 273.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 7t0p TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7T0PB O60674 536 808 1132.0 E3W:901 Type1 Pseudo DFGin 5.5841 13.3753 None -73.4, 171.14 -67.99, 156.9 -65.04, -35.98 333.3, 36.74 84.58, -160.86 out-na out 11.6751 Saltbr-na 999.0 HRD-in -82.44, -59.87 91.7, -5.68 na-out-out SNCaoo out-out ActLoopNT-out 9.5252 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -63.77, -34.38 APE9-dihe-out -70.23, -20.91 APE8-dihe-out -95.01, 13.79 APE8-rot-na 294.77 APE67-dihe-out -106.03, 28.99 -67.37, 133.92 APE12-dist-na 10.0828 APE11-dist-na 11.624 APE10-dist-na 16.2602 APE9-dist-out 12.9567 W659A,W777A,F794H None None XRAY 2.04 0.197 0.247 B 289.0 273.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 7t0p TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

PDB: 7T0P — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 7T0PA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-1 JAK2_HUMAN 7T0PA O60674 536 808 1132.0 E3W:901 Type1 Pseudo DFGin 5.5356 13.4525 None -71.36, 169.62 -64.37, 154.19 -64.4, -34.91 335.03, 35.41 82.73, -164.25 out-na out 11.6251 Saltbr-na 999.0 HRD-in -78.49, -60.16 92.47, -7.36 na-out-out SNCaoo out-out ActLoopNT-out 9.4113 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -60.7, -41.68 APE9-dihe-out -61.62, -27.73 APE8-dihe-out -89.13, 13.42 APE8-rot-na 292.46 APE67-dihe-out -104.69, 27.09 -67.15, 136.9 APE12-dist-na 10.1283 APE11-dist-na 11.4772 APE10-dist-na 16.1721 APE9-dist-out 12.8246 W659A,W777A,F794H None None XRAY 2.04 0.197 0.247 A 289.0 273.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 7t0p Homo sapiens TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2
TYR JAK2-1 JAK2_HUMAN 7T0PB O60674 536 808 1132.0 E3W:901 Type1 Pseudo DFGin 5.5841 13.3753 None -73.4, 171.14 -67.99, 156.9 -65.04, -35.98 333.3, 36.74 84.58, -160.86 out-na out 11.6751 Saltbr-na 999.0 HRD-in -82.44, -59.87 91.7, -5.68 na-out-out SNCaoo out-out ActLoopNT-out 9.5252 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -63.77, -34.38 APE9-dihe-out -70.23, -20.91 APE8-dihe-out -95.01, 13.79 APE8-rot-na 294.77 APE67-dihe-out -106.03, 28.99 -67.37, 133.92 APE12-dist-na 10.0828 APE11-dist-na 11.624 APE10-dist-na 16.2602 APE9-dist-out 12.9567 W659A,W777A,F794H None None XRAY 2.04 0.197 0.247 B 289.0 273.0 0 24 24 0 [[545, 807], [849, 1125]] 2.0 7t0p Homo sapiens TYR_JAK2-1_HUMAN TYR 1.9e-64 223.4 2.0 260.0 259.0 698 699 700 702 704 581 597 601 670 672 671 673.0 735 722 717 716 715 714 713 712 711 627 Tyrosine-protein kinase JAK2

PDB: 7T0P — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name