Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | RET | RET_HUMAN | 7RUNA | P07949 | 705 | 1012 | 1114.0 | 7QU:1102 | Type1.5_Back | Inactive | DFGin | 6.628 | 14.248 | BLAminus | -134.77, -173.78 | 63.39, 56.13 | -81.71, 19.24 | 291.69, 108.11 | -66.54, -40.45 | in-in | in | 7.588 | Saltbr-in | 3.458 | HRD-in | -98.1, -27.51 | 77.75, -68.34 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.687 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -96.35, -14.09 | APE9-dihe-in | -83.31, 135.75 | APE8-dihe-in | -58.85, 127.12 | APE8-rot-na | 17.23 | APE67-dihe-in | -70.31, -31.91 | -52.84, -32.19 | APE12-dist-na | 11.765 | APE11-dist-na | 10.714 | APE10-dist-na | 6.934 | APE9-dist-in | 6.239 | None | PTR809,PTR905,SEP909,PTR928 | PTR809,PTR905,SEP909,PTR928 | XRAY | 3.51 | 0.222 | 0.247 | A | 334 | 287 | 21 | 0 | 0 | 0 | [[724, 1007]] | 1.0 | 7run | TYR_RET_HUMAN | TYR | 5.1e-101 | 343.3 | 1 | 261 | 261 | 891 | 892 | 893 | 895 | 897 | 758 | 775 | 779 | 871 | 873 | 872 | 874 | 933 | 921 | 916 | 915 | 914 | 913 | 912 | 911 | 910 | 805 | Proto-oncogene tyrosine-protein kinase receptor Ret |
| TYR | RET | RET_HUMAN | 7RUNB | P07949 | 706 | 1012 | 1114.0 | 7QU:1102 | Type1.5_Back | Inactive | DFGin | 6.479 | 14.172 | BLAminus | -134.95, -173.5 | 63.71, 56.59 | -81.67, 19.29 | 291.63, 107.9 | -66.46, -40.71 | in-in | in | 7.592 | Saltbr-in | 3.385 | HRD-in | -99.07, -30.7 | 75.06, -75.74 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.704 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -94.95, -13.05 | APE9-dihe-in | -82.84, 135.71 | APE8-dihe-in | -58.94, 126.93 | APE8-rot-na | 17.11 | APE67-dihe-in | -69.79, -32.06 | -52.79, -32.62 | APE12-dist-na | 11.867 | APE11-dist-na | 10.687 | APE10-dist-na | 6.82 | APE9-dist-in | 6.591 | None | PTR809,PTR905,SEP909,PTR928 | PTR809,PTR905,SEP909,PTR928 | XRAY | 3.51 | 0.222 | 0.247 | B | 334 | 288 | 19 | 0 | 0 | 0 | [[724, 1007]] | 1.0 | 7run | TYR_RET_HUMAN | TYR | 5.1e-101 | 343.3 | 1 | 261 | 261 | 891 | 892 | 893 | 895 | 897 | 758 | 775 | 779 | 871 | 873 | 872 | 874 | 933 | 921 | 916 | 915 | 914 | 913 | 912 | 911 | 910 | 805 | Proto-oncogene tyrosine-protein kinase receptor Ret |
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TYR | RET | RET_HUMAN | 7RUNA | P07949 | 705 | 1012 | 1114.0 | 7QU:1102 | Type1.5_Back | Inactive | DFGin | 6.628 | 14.248 | BLAminus | -134.77, -173.78 | 63.39, 56.13 | -81.71, 19.24 | 291.69, 108.11 | -66.54, -40.45 | in-in | in | 7.588 | Saltbr-in | 3.458 | HRD-in | -98.1, -27.51 | 77.75, -68.34 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.687 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -96.35, -14.09 | APE9-dihe-in | -83.31, 135.75 | APE8-dihe-in | -58.85, 127.12 | APE8-rot-na | 17.23 | APE67-dihe-in | -70.31, -31.91 | -52.84, -32.19 | APE12-dist-na | 11.765 | APE11-dist-na | 10.714 | APE10-dist-na | 6.934 | APE9-dist-in | 6.239 | None | PTR809,PTR905,SEP909,PTR928 | PTR809,PTR905,SEP909,PTR928 | XRAY | 3.51 | 0.222 | 0.247 | A | 334 | 287 | 21 | 0 | 0 | 0 | [[724, 1007]] | 1.0 | 7run | Homo sapiens | TYR_RET_HUMAN | TYR | 5.1e-101 | 343.3 | 1 | 261 | 261 | 891 | 892 | 893 | 895 | 897 | 758 | 775 | 779 | 871 | 873 | 872 | 874 | 933 | 921 | 916 | 915 | 914 | 913 | 912 | 911 | 910 | 805 | Proto-oncogene tyrosine-protein kinase receptor Ret |
| TYR | RET | RET_HUMAN | 7RUNB | P07949 | 706 | 1012 | 1114.0 | 7QU:1102 | Type1.5_Back | Inactive | DFGin | 6.479 | 14.172 | BLAminus | -134.95, -173.5 | 63.71, 56.59 | -81.67, 19.29 | 291.63, 107.9 | -66.46, -40.71 | in-in | in | 7.592 | Saltbr-in | 3.385 | HRD-in | -99.07, -30.7 | 75.06, -75.74 | in-in-out | SNCiio | in-out | ActLoopNT-in | 2.704 | ActLoopCT-out | TYR | APEdihe_oiiai | APEdist_aaai | APE10-dihe-out | -94.95, -13.05 | APE9-dihe-in | -82.84, 135.71 | APE8-dihe-in | -58.94, 126.93 | APE8-rot-na | 17.11 | APE67-dihe-in | -69.79, -32.06 | -52.79, -32.62 | APE12-dist-na | 11.867 | APE11-dist-na | 10.687 | APE10-dist-na | 6.82 | APE9-dist-in | 6.591 | None | PTR809,PTR905,SEP909,PTR928 | PTR809,PTR905,SEP909,PTR928 | XRAY | 3.51 | 0.222 | 0.247 | B | 334 | 288 | 19 | 0 | 0 | 0 | [[724, 1007]] | 1.0 | 7run | Homo sapiens | TYR_RET_HUMAN | TYR | 5.1e-101 | 343.3 | 1 | 261 | 261 | 891 | 892 | 893 | 895 | 897 | 758 | 775 | 779 | 871 | 873 | 872 | 874 | 933 | 921 | 916 | 915 | 914 | 913 | 912 | 911 | 910 | 805 | Proto-oncogene tyrosine-protein kinase receptor Ret |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
Hover over column headers for tooltip help
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|