| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OA | O75116 | 24 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.0154 | 13.121 | BLAminus | -129.99, 173.74 | 63.69, 84.38 | -107.33, 35.64 | 304.65, 101.12 | -72.03, -45.78 | in-in | in | 8.633 | Saltbr-in | 2.7576 | HRD-in | -67.26, -41.63 | 68.26, 2.18 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2221 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iooi | APE10-dihe-na | -114.07, 159.24 | APE9-dihe-na | -78.74, -160.5 | APE8-dihe-in | -69.68, 142.93 | APE8-rot-out | 53.5 | APE67-dihe-in | -55.96, -37.76 | -73.63, -19.8 | APE12-dist-in | 10.3281 | APE11-dist-out | 7.6374 | APE10-dist-out | 8.5783 | APE9-dist-in | 5.5052 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | A | 399.0 | 388.0 | 2 | 29 | 27 | 2 | [[92, 354]] | 1.0 | 7p6o | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OB | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.03 | 13.1172 | BLAminus | -130.02, 173.83 | 63.76, 84.52 | -107.31, 35.45 | 304.31, 101.62 | -71.82, -45.98 | in-in | in | 8.6543 | Saltbr-in | 2.7589 | HRD-in | -67.3, -41.49 | 68.16, 2.38 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2198 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 142.81 | APE8-rot-out | 53.14 | APE67-dihe-in | -56.68, -36.81 | -74.24, -19.91 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | B | 399.0 | 379.0 | 12 | 29 | 22 | 7 | [[92, 354]] | 1.0 | 7p6o | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OD | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.0295 | 13.1154 | BLAminus | -130.14, 174.07 | 63.77, 84.08 | -107.41, 35.57 | 304.55, 101.36 | -72.14, -45.87 | in-in | in | 8.6845 | Saltbr-in | 2.7583 | HRD-in | -67.39, -41.46 | 68.03, 2.41 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2201 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_inii | APE10-dihe-na | 999.0, 157.1 | APE9-dihe-na | 77.73, 175.48 | APE8-dihe-in | -69.48, 142.35 | APE8-rot-out | 52.81 | APE67-dihe-in | -56.84, -36.56 | -74.86, -19.55 | APE12-dist-in | 9.4752 | APE11-dist-none | 999.0 | APE10-dist-in | 5.3825 | APE9-dist-in | 5.499 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | D | 399.0 | 384.0 | 5 | 29 | 28 | 1 | [[92, 354]] | 1.0 | 7p6o | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OE | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.0376 | 13.1036 | BLAminus | -130.06, 173.52 | 64.1, 84.65 | -107.82, 35.44 | 304.2, 101.68 | -73.02, -45.03 | in-in | in | 8.6513 | Saltbr-in | 2.7586 | HRD-in | -67.66, -41.03 | 68.51, 2.53 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2252 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 143.09 | APE8-rot-out | 52.96 | APE67-dihe-in | -55.98, -37.45 | -73.98, -19.61 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | E | 399.0 | 385.0 | 5 | 29 | 24 | 5 | [[92, 354]] | 1.0 | 7p6o | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OF | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.0289 | 13.1241 | BLAminus | -130.14, 174.06 | 63.83, 84.14 | -107.45, 35.57 | 304.61, 101.55 | -72.27, -45.71 | in-in | in | 8.6797 | Saltbr-in | 2.7572 | HRD-in | -67.35, -41.53 | 67.92, 2.62 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2207 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -115.42, 157.65 | APE9-dihe-na | 77.78, 174.44 | APE8-dihe-in | -69.32, 142.43 | APE8-rot-out | 52.91 | APE67-dihe-in | -56.82, -36.56 | -74.83, -19.59 | APE12-dist-in | 11.2408 | APE11-dist-in | 10.6912 | APE10-dist-in | 5.3659 | APE9-dist-in | 5.4727 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | F | 399.0 | 383.0 | 6 | 29 | 28 | 1 | [[92, 354]] | 1.0 | 7p6o | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OC | O75116 | 22 | 417 | 1388.0 | 5YK:501 | Type1.5_Front | None | DFGin | 6.0199 | 13.0977 | BLAminus | -129.77, 174.02 | 63.85, 83.94 | -107.22, 35.66 | 304.43, 101.43 | -71.69, -46.2 | in-in | in | 8.6693 | Saltbr-in | 2.758 | HRD-in | -67.24, -41.54 | 67.86, 2.47 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.2217 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -56.0, -37.44 | 999.0, -18.95 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | C | 399.0 | 377.0 | 13 | 29 | 22 | 7 | [[92, 354]] | 1.0 | 7p6o | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OG | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1.5_Front | Inactive | DFGin | 6.0297 | 13.0932 | BLAminus | -130.18, 173.76 | 63.87, 84.33 | -107.4, 35.32 | 304.41, 101.68 | -72.33, -45.62 | in-in | in | 8.6573 | Saltbr-in | 2.7572 | HRD-in | -67.47, -41.36 | 68.16, 2.55 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2227 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 143.09 | APE8-rot-out | 52.99 | APE67-dihe-in | -56.93, -36.54 | -73.99, -19.83 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | G | 399.0 | 381.0 | 8 | 29 | 24 | 5 | [[92, 354]] | 1.0 | 7p6o | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OH | O75116 | 24 | 417 | 1388.0 | 5YK:501 | Type1.5_Front | None | DFGin | 6.0306 | 13.1422 | BLAminus | -130.18, 173.86 | 63.9, 84.23 | -107.39, 35.65 | 304.66, 101.19 | -71.86, -45.96 | in-in | in | 8.6848 | Saltbr-in | 2.7574 | HRD-in | -67.2, -41.51 | 67.93, 2.34 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.2184 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -56.17, -36.5 | 999.0, -17.01 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | H | 399.0 | 369.0 | 19 | 29 | 15 | 14 | [[92, 354]] | 1.0 | 7p6o | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OA | O75116 | 24 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.0154 | 13.121 | BLAminus | -129.99, 173.74 | 63.69, 84.38 | -107.33, 35.64 | 304.65, 101.12 | -72.03, -45.78 | in-in | in | 8.633 | Saltbr-in | 2.7576 | HRD-in | -67.26, -41.63 | 68.26, 2.18 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2221 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iooi | APE10-dihe-na | -114.07, 159.24 | APE9-dihe-na | -78.74, -160.5 | APE8-dihe-in | -69.68, 142.93 | APE8-rot-out | 53.5 | APE67-dihe-in | -55.96, -37.76 | -73.63, -19.8 | APE12-dist-in | 10.3281 | APE11-dist-out | 7.6374 | APE10-dist-out | 8.5783 | APE9-dist-in | 5.5052 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | A | 399.0 | 388.0 | 2 | 29 | 27 | 2 | [[92, 354]] | 1.0 | 7p6o | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OB | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.03 | 13.1172 | BLAminus | -130.02, 173.83 | 63.76, 84.52 | -107.31, 35.45 | 304.31, 101.62 | -71.82, -45.98 | in-in | in | 8.6543 | Saltbr-in | 2.7589 | HRD-in | -67.3, -41.49 | 68.16, 2.38 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2198 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 142.81 | APE8-rot-out | 53.14 | APE67-dihe-in | -56.68, -36.81 | -74.24, -19.91 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | B | 399.0 | 379.0 | 12 | 29 | 22 | 7 | [[92, 354]] | 1.0 | 7p6o | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OD | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.0295 | 13.1154 | BLAminus | -130.14, 174.07 | 63.77, 84.08 | -107.41, 35.57 | 304.55, 101.36 | -72.14, -45.87 | in-in | in | 8.6845 | Saltbr-in | 2.7583 | HRD-in | -67.39, -41.46 | 68.03, 2.41 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2201 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_inii | APE10-dihe-na | 999.0, 157.1 | APE9-dihe-na | 77.73, 175.48 | APE8-dihe-in | -69.48, 142.35 | APE8-rot-out | 52.81 | APE67-dihe-in | -56.84, -36.56 | -74.86, -19.55 | APE12-dist-in | 9.4752 | APE11-dist-none | 999.0 | APE10-dist-in | 5.3825 | APE9-dist-in | 5.499 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | D | 399.0 | 384.0 | 5 | 29 | 28 | 1 | [[92, 354]] | 1.0 | 7p6o | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OE | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.0376 | 13.1036 | BLAminus | -130.06, 173.52 | 64.1, 84.65 | -107.82, 35.44 | 304.2, 101.68 | -73.02, -45.03 | in-in | in | 8.6513 | Saltbr-in | 2.7586 | HRD-in | -67.66, -41.03 | 68.51, 2.53 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2252 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 143.09 | APE8-rot-out | 52.96 | APE67-dihe-in | -55.98, -37.45 | -73.98, -19.61 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | E | 399.0 | 385.0 | 5 | 29 | 24 | 5 | [[92, 354]] | 1.0 | 7p6o | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OF | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1 | Inactive | DFGin | 6.0289 | 13.1241 | BLAminus | -130.14, 174.06 | 63.83, 84.14 | -107.45, 35.57 | 304.61, 101.55 | -72.27, -45.71 | in-in | in | 8.6797 | Saltbr-in | 2.7572 | HRD-in | -67.35, -41.53 | 67.92, 2.62 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2207 | ActLoopCT-out | nonTYR | APEdihe_aaioi | APEdist_iiii | APE10-dihe-na | -115.42, 157.65 | APE9-dihe-na | 77.78, 174.44 | APE8-dihe-in | -69.32, 142.43 | APE8-rot-out | 52.91 | APE67-dihe-in | -56.82, -36.56 | -74.83, -19.59 | APE12-dist-in | 11.2408 | APE11-dist-in | 10.6912 | APE10-dist-in | 5.3659 | APE9-dist-in | 5.4727 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | F | 399.0 | 383.0 | 6 | 29 | 28 | 1 | [[92, 354]] | 1.0 | 7p6o | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OC | O75116 | 22 | 417 | 1388.0 | 5YK:501 | Type1.5_Front | None | DFGin | 6.0199 | 13.0977 | BLAminus | -129.77, 174.02 | 63.85, 83.94 | -107.22, 35.66 | 304.43, 101.43 | -71.69, -46.2 | in-in | in | 8.6693 | Saltbr-in | 2.758 | HRD-in | -67.24, -41.54 | 67.86, 2.47 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.2217 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -56.0, -37.44 | 999.0, -18.95 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | C | 399.0 | 377.0 | 13 | 29 | 22 | 7 | [[92, 354]] | 1.0 | 7p6o | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OG | O75116 | 25 | 417 | 1388.0 | 5YK:501 | Type1.5_Front | Inactive | DFGin | 6.0297 | 13.0932 | BLAminus | -130.18, 173.76 | 63.87, 84.33 | -107.4, 35.32 | 304.41, 101.68 | -72.33, -45.62 | in-in | in | 8.6573 | Saltbr-in | 2.7572 | HRD-in | -67.47, -41.36 | 68.16, 2.55 | in-in-out | SNCiio | in-out | ActLoopNT-in | 3.2227 | ActLoopCT-out | nonTYR | APEdihe_aanoi | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 143.09 | APE8-rot-out | 52.99 | APE67-dihe-in | -56.93, -36.54 | -73.99, -19.83 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | G | 399.0 | 381.0 | 8 | 29 | 24 | 5 | [[92, 354]] | 1.0 | 7p6o | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| AGC | ROCK2 | ROCK2_HUMAN | 7P6OH | O75116 | 24 | 417 | 1388.0 | 5YK:501 | Type1.5_Front | None | DFGin | 6.0306 | 13.1422 | BLAminus | -130.18, 173.86 | 63.9, 84.23 | -107.39, 35.65 | 304.66, 101.19 | -71.86, -45.96 | in-in | in | 8.6848 | Saltbr-in | 2.7574 | HRD-in | -67.2, -41.51 | 67.93, 2.34 | in-in-none | SNCiin | in-none | ActLoopNT-in | 3.2184 | ActLoopCT-none | nonTYR | APEdihe_aannn | APEdist_nnnn | APE10-dihe-na | 999.0, 999.0 | APE9-dihe-na | 999.0, 999.0 | APE8-dihe-none | 999.0, 999.0 | APE8-rot-none | 999.0 | APE67-dihe-none | -56.17, -36.5 | 999.0, -17.01 | APE12-dist-none | 999.0 | APE11-dist-none | 999.0 | APE10-dist-none | 999.0 | APE9-dist-none | 999.0 | None | None | None | XRAY | 2.75 | 0.241 | 0.286 | H | 399.0 | 369.0 | 19 | 29 | 15 | 14 | [[92, 354]] | 1.0 | 7p6o | Homo sapiens | AGC_ROCK2_HUMAN | AGC | 2.3e-93 | 318.0 | 1.0 | 260.0 | 260.0 | 231 | 232 | 233 | 235 | 237 | 121 | 140 | 144 | 211 | 213 | 212 | 214.0 | 276 | 260 | 255 | 254 | 253 | 252 | 251 | 250 | 249 | 170 | Rho-associated protein kinase 2 |
| Spatial label | Dihedral label | Number of Chains | Percent | Representative |
|---|
| Group | Gene | SwissprotID | PDB | UniprotID | First_obs_res | Last_obs_res | Length_Unp | Ligand | Ligand_type | Activity_label | Spatial_label | Phe_Glu4_dis | Phe_Lys_dis | Dihedral_label | XDFG φ,ψ |
DFG-Asp φ,ψ |
DFG-Phe φ,ψ |
DFG-Phe χ1,χ2 |
DFG-Gly φ,ψ |
ChelixSaltbr_label | Chelix_label | Lys_Glu_dis | Saltbr_label | LysNZ_GluOE_dis | HRD_label | His φ,ψ | Arg φ,ψ | SNC_label | SNCpymol_label | ActLoop_label | ActLoopNT_label | DFG6_XHRD_dis | ActLoopCT_label | APEtype | APEdihe_label | APEdist_label | APE10_dihe_label | APE10 φ,ψ | APE9_dihe_label | APE9 φ,ψ | APE8_dihe_label | APE8 φ,ψ | APE8_rotamer_label | APE8 χ1 | APE67_label | APE6 φ,ψ | APE7 φ,ψ | APE12_dist_label | APE12_DFG4_dis | APE11_dist_label | APE11_DFG4_dis | APE10_dist_label | APE10_DFG4_dis | APE9_dist_label | APE9_Arg_dis | Chain_mut | Chain_phos | Modified_aa | Method | Resolution | Rvalue | FreeRvalue | Chain_id | ChainLen | Ordered_residues | DomainBreak | ActLoopLength | ActLoopResolvedResidues | ActLoopDisorderedResidues | Kinase_domains_Unp | N_Kinase_domains_Unp | pdb | Species | Kincore_name | hmm | Evalue | Score | hmmbeg | hmmend | hmmlen | XDFGnum | DFGnum | PHEnum | DFG4num | DFG6num | LYSnum | GLUnum | GLU4num | XHRDnum | ARGnum | HRDnum | HRDaspnum | aFaspnum | APEnum | APE6num | APE7num | APE8num | APE9num | APE10num | APE11num | APE12num | Hinge1num | Protein_name |
|---|