PDB: 7N9G — TYR ABL1_HUMAN

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 2 66.7% 7N9GA
DFGin BLAminus 1 33.3% 7N9GB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ABL1 ABL1_HUMAN 7N9GB P00519 233 498 1130.0 STI:60601,1N1:60602 Allosteric,Type1 Active DFGin 6.7541 13.4449 BLAminus -122.97, -168.58 58.54, 84.79 -109.7, 15.38 305.77, 104.92 -56.72, -36.19 in-in in 7.8072 Saltbr-in 2.716 HRD-in -94.83, -54.73 76.06, 6.03 in-in-in SNCiii in-in ActLoopNT-in 3.0408 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.97, 124.86 APE9-dihe-in -118.42, 152.72 APE8-dihe-in -70.17, 95.62 APE8-rot-na 28.18 APE67-dihe-in -73.36, -13.19 -53.92, -45.07 APE12-dist-na 14.9514 APE11-dist-na 10.1213 APE10-dist-na 12.2789 APE9-dist-in 7.1369 None None None XRAY 2.2 0.219 0.251 B 271.0 264.0 2 29 29 0 [[242, 495]] 1.0 7n9g TYR_ABL1_HUMAN TYR 2.2e-100 341.2 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7N9GA P00519 233 498 1130.0 STI:60601,1N1:60602 Allosteric,Type1 Inactive DFGinter 10.4212 8.1868 None -69.43, 136.44 -123.08, 27.78 -75.4, -30.96 178.85, 77.99 -98.31, 50.2 in-out in 8.8784 Saltbr-out 9.7861 HRD-out -92.88, 142.81 -110.01, 0.88 out-out-none SNCoon out-none ActLoopNT-out 5.5443 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 170.84 APE8-dihe-in -72.01, 95.09 APE8-rot-na 30.25 APE67-dihe-in -73.75, -10.66 -54.08, -44.56 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.8503 None None None XRAY 2.2 0.219 0.251 A 271.0 250.0 16 29 16 13 [[242, 495]] 1.0 7n9g TYR_ABL1_HUMAN TYR 2.2e-100 341.2 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7N9GC P00519 234 499 1130.0 STI:60601,1N1:60602 Allosteric,Type1 Inactive DFGinter 10.016 7.7618 None -68.53, 140.81 -120.26, 3.31 -57.57, -42.4 182.82, 108.58 -86.96, 40.71 in-none in 9.4392 Saltbr-none 999.0 HRD-out -106.92, 134.12 -80.26, -30.58 none-out-none SNCnon out-none ActLoopNT-out 5.4779 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 96.82 APE8-dihe-in -65.53, 99.76 APE8-rot-na 23.57 APE67-dihe-in -73.61, -20.46 -60.17, -42.86 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.8914 None None None XRAY 2.2 0.219 0.251 C 271.0 233.0 33 29 24 5 [[242, 495]] 1.0 7n9g TYR_ABL1_HUMAN TYR 2.2e-100 341.2 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1

PDB: 7N9G — TYR ABL1_HUMAN

Total number of chains: 3
Active chains: 1
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGinter None 2 66.7% 7N9GA
DFGin BLAminus 1 33.3% 7N9GB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR ABL1 ABL1_HUMAN 7N9GB P00519 233 498 1130.0 STI:60601,1N1:60602 Allosteric,Type1 Active DFGin 6.7541 13.4449 BLAminus -122.97, -168.58 58.54, 84.79 -109.7, 15.38 305.77, 104.92 -56.72, -36.19 in-in in 7.8072 Saltbr-in 2.716 HRD-in -94.83, -54.73 76.06, 6.03 in-in-in SNCiii in-in ActLoopNT-in 3.0408 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -97.97, 124.86 APE9-dihe-in -118.42, 152.72 APE8-dihe-in -70.17, 95.62 APE8-rot-na 28.18 APE67-dihe-in -73.36, -13.19 -53.92, -45.07 APE12-dist-na 14.9514 APE11-dist-na 10.1213 APE10-dist-na 12.2789 APE9-dist-in 7.1369 None None None XRAY 2.2 0.219 0.251 B 271.0 264.0 2 29 29 0 [[242, 495]] 1.0 7n9g Homo sapiens TYR_ABL1_HUMAN TYR 2.2e-100 341.2 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7N9GA P00519 233 498 1130.0 STI:60601,1N1:60602 Allosteric,Type1 Inactive DFGinter 10.4212 8.1868 None -69.43, 136.44 -123.08, 27.78 -75.4, -30.96 178.85, 77.99 -98.31, 50.2 in-out in 8.8784 Saltbr-out 9.7861 HRD-out -92.88, 142.81 -110.01, 0.88 out-out-none SNCoon out-none ActLoopNT-out 5.5443 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 170.84 APE8-dihe-in -72.01, 95.09 APE8-rot-na 30.25 APE67-dihe-in -73.75, -10.66 -54.08, -44.56 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 5.8503 None None None XRAY 2.2 0.219 0.251 A 271.0 250.0 16 29 16 13 [[242, 495]] 1.0 7n9g Homo sapiens TYR_ABL1_HUMAN TYR 2.2e-100 341.2 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1
TYR ABL1 ABL1_HUMAN 7N9GC P00519 234 499 1130.0 STI:60601,1N1:60602 Allosteric,Type1 Inactive DFGinter 10.016 7.7618 None -68.53, 140.81 -120.26, 3.31 -57.57, -42.4 182.82, 108.58 -86.96, 40.71 in-none in 9.4392 Saltbr-none 999.0 HRD-out -106.92, 134.12 -80.26, -30.58 none-out-none SNCnon out-none ActLoopNT-out 5.4779 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 96.82 APE8-dihe-in -65.53, 99.76 APE8-rot-na 23.57 APE67-dihe-in -73.61, -20.46 -60.17, -42.86 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 6.8914 None None None XRAY 2.2 0.219 0.251 C 271.0 233.0 33 29 24 5 [[242, 495]] 1.0 7n9g Homo sapiens TYR_ABL1_HUMAN TYR 2.2e-100 341.2 1.0 260.0 260.0 380 381 382 384 386 271 286 290 360 362 361 363.0 421 409 404 403 402 401 400 399 398 316 Tyrosine-protein kinase ABL1

PDB: 7N9G — TYR ABL1_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name