PDB: 7JXW — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 7JXWC

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXWA P00533 700 1007 1210.0 YY3:1301,VNS:1302 Type1,Type3 Inactive DFGin 4.579 14.666 BLBplus -138.64, 168.46 50.29, 44.7 -88.71, 170.77 52.75, 84.47 69.65, 17.94 out-out out 13.1767 Saltbr-out 9.9327 HRD-in -64.27, -62.7 83.56, -10.71 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -29.5 APE8-dihe-in -90.52, 58.97 APE8-rot-na 25.71 APE67-dihe-in -73.18, -5.87 -63.78, -37.62 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.655 T790M,V948R None None XRAY 2.5 0.276 0.319 A 331.0 288.0 20 30 14 16 [[712, 970]] 1.0 7jxw TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWB P00533 700 1007 1210.0 YY3:1301,VNS:1302 Type1,Type3 Inactive DFGin 4.8888 14.5479 BLBplus -137.39, 167.04 52.05, 48.78 -89.33, 172.11 49.0, 84.75 70.86, 14.53 out-out out 12.8795 Saltbr-out 9.6401 HRD-in -63.98, -61.04 82.53, -9.45 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 67.58 APE8-rot-na 26.38 APE67-dihe-in -75.13, -4.52 -61.59, -34.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T790M,V948R None None XRAY 2.5 0.276 0.319 B 331.0 291.0 17 30 13 17 [[712, 970]] 1.0 7jxw TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWC P00533 700 1007 1210.0 YY3:1301,VNS:1302 Type1,Type3 Inactive DFGin 4.6443 14.3085 BLBplus -142.67, 169.6 56.07, 43.83 -87.93, 169.01 48.26, 81.62 68.95, 14.82 out-out out 13.3941 Saltbr-out 10.0598 HRD-in -68.52, -63.21 83.53, -10.12 out-out-none SNCoon out-none ActLoopNT-out 9.3722 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 123.99 APE8-dihe-in -72.85, 69.17 APE8-rot-na 25.57 APE67-dihe-in -79.13, -5.07 -61.58, -38.99 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7407 T790M,V948R None None XRAY 2.5 0.276 0.319 C 331.0 293.0 15 30 15 15 [[712, 970]] 1.0 7jxw TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWD P00533 700 1007 1210.0 YY3:1301,VNS:1302 Type1,Type3 Inactive DFGin 4.4743 14.2146 BLBplus -140.27, 167.25 54.64, 43.57 -89.93, 170.58 53.09, 83.38 70.73, 14.16 out-out out 13.2865 Saltbr-out 10.1761 HRD-in -66.78, -61.63 83.28, -9.7 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.01 APE8-dihe-in -78.05, 71.87 APE8-rot-na 25.04 APE67-dihe-in -75.98, -6.06 -65.38, -38.44 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.0117 T790M,V948R None None XRAY 2.5 0.276 0.319 D 331.0 287.0 21 30 13 17 [[712, 970]] 1.0 7jxw TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXW — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 4 100.0% 7JXWC

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXWA P00533 700 1007 1210.0 YY3:1301,VNS:1302 Type1,Type3 Inactive DFGin 4.579 14.666 BLBplus -138.64, 168.46 50.29, 44.7 -88.71, 170.77 52.75, 84.47 69.65, 17.94 out-out out 13.1767 Saltbr-out 9.9327 HRD-in -64.27, -62.7 83.56, -10.71 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, -29.5 APE8-dihe-in -90.52, 58.97 APE8-rot-na 25.71 APE67-dihe-in -73.18, -5.87 -63.78, -37.62 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.655 T790M,V948R None None XRAY 2.5 0.276 0.319 A 331.0 288.0 20 30 14 16 [[712, 970]] 1.0 7jxw Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWB P00533 700 1007 1210.0 YY3:1301,VNS:1302 Type1,Type3 Inactive DFGin 4.8888 14.5479 BLBplus -137.39, 167.04 52.05, 48.78 -89.33, 172.11 49.0, 84.75 70.86, 14.53 out-out out 12.8795 Saltbr-out 9.6401 HRD-in -63.98, -61.04 82.53, -9.45 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nnnai APEdist_aaan APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 999.0 APE8-dihe-none 999.0, 67.58 APE8-rot-na 26.38 APE67-dihe-in -75.13, -4.52 -61.59, -34.64 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-none 999.0 T790M,V948R None None XRAY 2.5 0.276 0.319 B 331.0 291.0 17 30 13 17 [[712, 970]] 1.0 7jxw Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWC P00533 700 1007 1210.0 YY3:1301,VNS:1302 Type1,Type3 Inactive DFGin 4.6443 14.3085 BLBplus -142.67, 169.6 56.07, 43.83 -87.93, 169.01 48.26, 81.62 68.95, 14.82 out-out out 13.3941 Saltbr-out 10.0598 HRD-in -68.52, -63.21 83.53, -10.12 out-out-none SNCoon out-none ActLoopNT-out 9.3722 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 123.99 APE8-dihe-in -72.85, 69.17 APE8-rot-na 25.57 APE67-dihe-in -79.13, -5.07 -61.58, -38.99 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7407 T790M,V948R None None XRAY 2.5 0.276 0.319 C 331.0 293.0 15 30 15 15 [[712, 970]] 1.0 7jxw Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXWD P00533 700 1007 1210.0 YY3:1301,VNS:1302 Type1,Type3 Inactive DFGin 4.4743 14.2146 BLBplus -140.27, 167.25 54.64, 43.57 -89.93, 170.58 53.09, 83.38 70.73, 14.16 out-out out 13.2865 Saltbr-out 10.1761 HRD-in -66.78, -61.63 83.28, -9.7 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.01 APE8-dihe-in -78.05, 71.87 APE8-rot-na 25.04 APE67-dihe-in -75.98, -6.06 -65.38, -38.44 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.0117 T790M,V948R None None XRAY 2.5 0.276 0.319 D 331.0 287.0 21 30 13 17 [[712, 970]] 1.0 7jxw Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXW — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name