PDB: 7JXP — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7JXPA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXPA P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.747 14.617 BLBplus -136.18, 166.76 64.66, 34.04 -92.53, 168.9 56.02, 85.41 85.63, 11.86 out-out out 13.988 Saltbr-out 14.307 HRD-in -74.54, -64.28 89.28, -17.63 out-out-out SNCooo out-out ActLoopNT-out 7.509 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -97.63, -15.8 APE9-dihe-in -113.05, 126.54 APE8-dihe-in -83.29, 68.9 APE8-rot-na 33.94 APE67-dihe-in -74.36, -3.96 -52.3, -47.62 APE12-dist-na 17.096 APE11-dist-na 14.956 APE10-dist-na 11.693 APE9-dist-in 7.406 T790M,V948R None None XRAY 2.16 0.214 0.247 A 331 308 0 0 0 0 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPB P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.671 14.511 BLBplus -135.21, 165.17 64.35, 37.85 -90.15, 169.17 53.82, 91.67 84.59, 7.68 out-out out 13.756 Saltbr-out 13.888 HRD-in -70.65, -63.17 87.36, -17.28 out-out-out SNCooo out-out ActLoopNT-out 7.592 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -97.44, -17.16 APE9-dihe-in -126.66, 129.43 APE8-dihe-in -78.52, 67.74 APE8-rot-na 34.72 APE67-dihe-in -76.32, -3.64 -51.52, -45.13 APE12-dist-na 17.438 APE11-dist-na 15.214 APE10-dist-na 12.275 APE9-dist-in 7.617 T790M,V948R None None XRAY 2.16 0.214 0.247 B 331 308 0 0 0 0 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPD P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.766 14.661 BLBplus -135.69, 167.35 65.6, 33.96 -89.97, 168.72 55.6, 87.2 84.96, 9.82 out-out out 13.526 Saltbr-out 11.283 HRD-in -71.06, -65.03 87.13, -14.24 out-out-none SNCoon out-none ActLoopNT-out 8.004 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.01 APE8-dihe-in -77.89, 69.26 APE8-rot-na 33.29 APE67-dihe-in -74.9, -2.69 -52.27, -42.76 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.744 T790M,V948R None None XRAY 2.16 0.214 0.247 D 331 294 14 0 0 14 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPF P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.974 14.702 BLBplus -136.82, 166.82 61.14, 36.57 -93.57, 171.83 53.4, 92.66 83.03, -0.51 out-out out 13.674 Saltbr-out 11.57 HRD-in -71.01, -63.71 87.17, -13.68 out-out-none SNCoon out-none ActLoopNT-out 9.118 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 127.33 APE8-dihe-in -78.62, 69.48 APE8-rot-na 32.72 APE67-dihe-in -72.69, -4.28 -52.16, -45.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.621 T790M,V948R None None XRAY 2.16 0.214 0.247 F 331 294 14 0 0 14 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPC P00533 700 1007 1210.0 JBJ:1101,YY3:1102 Type3,Type1 Inactive DFGin 4.791 14.489 BLBplus -135.14, 166.93 58.75, 39.54 -88.72, 165.62 50.16, 82.07 80.91, 11.4 out-out out 13.215 Saltbr-out 10.01 HRD-in -71.03, -65.61 90.59, -16.24 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.4 APE8-dihe-in -78.08, 71.31 APE8-rot-na 31.49 APE67-dihe-in -74.31, -4.1 -55.2, -45.03 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.734 T790M,V948R None None XRAY 2.16 0.214 0.247 C 331 292 16 0 0 16 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPE P00533 700 1007 1210.0 JBJ:1101,YY3:1102 Type3,Type1 Inactive DFGin 5.017 14.71 BLBplus -135.91, 163.38 57.21, 38.2 -87.34, 167.11 54.31, 95.16 79.16, 16.43 out-out out 13.581 Saltbr-out 11.008 HRD-in -68.91, -62.25 86.58, -12.8 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 129.81 APE8-dihe-in -81.71, 69.65 APE8-rot-na 31.8 APE67-dihe-in -77.02, -5.14 -52.47, -41.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.46 T790M,V948R None None XRAY 2.16 0.214 0.247 E 331 287 16 0 0 16 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXP — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7JXPA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXPA P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.747 14.617 BLBplus -136.18, 166.76 64.66, 34.04 -92.53, 168.9 56.02, 85.41 85.63, 11.86 out-out out 13.988 Saltbr-out 14.307 HRD-in -74.54, -64.28 89.28, -17.63 out-out-out SNCooo out-out ActLoopNT-out 7.509 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -97.63, -15.8 APE9-dihe-in -113.05, 126.54 APE8-dihe-in -83.29, 68.9 APE8-rot-na 33.94 APE67-dihe-in -74.36, -3.96 -52.3, -47.62 APE12-dist-na 17.096 APE11-dist-na 14.956 APE10-dist-na 11.693 APE9-dist-in 7.406 T790M,V948R None None XRAY 2.16 0.214 0.247 A 331 308 0 0 0 0 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPB P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.671 14.511 BLBplus -135.21, 165.17 64.35, 37.85 -90.15, 169.17 53.82, 91.67 84.59, 7.68 out-out out 13.756 Saltbr-out 13.888 HRD-in -70.65, -63.17 87.36, -17.28 out-out-out SNCooo out-out ActLoopNT-out 7.592 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -97.44, -17.16 APE9-dihe-in -126.66, 129.43 APE8-dihe-in -78.52, 67.74 APE8-rot-na 34.72 APE67-dihe-in -76.32, -3.64 -51.52, -45.13 APE12-dist-na 17.438 APE11-dist-na 15.214 APE10-dist-na 12.275 APE9-dist-in 7.617 T790M,V948R None None XRAY 2.16 0.214 0.247 B 331 308 0 0 0 0 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPD P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.766 14.661 BLBplus -135.69, 167.35 65.6, 33.96 -89.97, 168.72 55.6, 87.2 84.96, 9.82 out-out out 13.526 Saltbr-out 11.283 HRD-in -71.06, -65.03 87.13, -14.24 out-out-none SNCoon out-none ActLoopNT-out 8.004 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.01 APE8-dihe-in -77.89, 69.26 APE8-rot-na 33.29 APE67-dihe-in -74.9, -2.69 -52.27, -42.76 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.744 T790M,V948R None None XRAY 2.16 0.214 0.247 D 331 294 14 0 0 14 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPF P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.974 14.702 BLBplus -136.82, 166.82 61.14, 36.57 -93.57, 171.83 53.4, 92.66 83.03, -0.51 out-out out 13.674 Saltbr-out 11.57 HRD-in -71.01, -63.71 87.17, -13.68 out-out-none SNCoon out-none ActLoopNT-out 9.118 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 127.33 APE8-dihe-in -78.62, 69.48 APE8-rot-na 32.72 APE67-dihe-in -72.69, -4.28 -52.16, -45.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.621 T790M,V948R None None XRAY 2.16 0.214 0.247 F 331 294 14 0 0 14 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPC P00533 700 1007 1210.0 JBJ:1101,YY3:1102 Type3,Type1 Inactive DFGin 4.791 14.489 BLBplus -135.14, 166.93 58.75, 39.54 -88.72, 165.62 50.16, 82.07 80.91, 11.4 out-out out 13.215 Saltbr-out 10.01 HRD-in -71.03, -65.61 90.59, -16.24 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.4 APE8-dihe-in -78.08, 71.31 APE8-rot-na 31.49 APE67-dihe-in -74.31, -4.1 -55.2, -45.03 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.734 T790M,V948R None None XRAY 2.16 0.214 0.247 C 331 292 16 0 0 16 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPE P00533 700 1007 1210.0 JBJ:1101,YY3:1102 Type3,Type1 Inactive DFGin 5.017 14.71 BLBplus -135.91, 163.38 57.21, 38.2 -87.34, 167.11 54.31, 95.16 79.16, 16.43 out-out out 13.581 Saltbr-out 11.008 HRD-in -68.91, -62.25 86.58, -12.8 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 129.81 APE8-dihe-in -81.71, 69.65 APE8-rot-na 31.8 APE67-dihe-in -77.02, -5.14 -52.47, -41.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.46 T790M,V948R None None XRAY 2.16 0.214 0.247 E 331 287 16 0 0 16 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXP — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name