PDB: 7JXP — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7JXPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXPA P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.7467 14.6167 BLBplus -136.18, 166.76 64.66, 34.04 -92.53, 168.9 56.02, 85.41 85.63, 11.86 out-out out 13.9879 Saltbr-out 14.3068 HRD-in -74.54, -64.28 89.28, -17.63 out-out-out SNCooo out-out ActLoopNT-out 7.5088 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -97.63, -15.8 APE9-dihe-in -113.05, 126.54 APE8-dihe-in -83.29, 68.9 APE8-rot-na 33.94 APE67-dihe-in -74.36, -3.96 -52.3, -47.62 APE12-dist-na 17.0956 APE11-dist-na 14.9557 APE10-dist-na 11.6928 APE9-dist-in 7.4058 T790M,V948R None None XRAY 2.16 0.214 0.247 A 331.0 308.0 0 30 30 0 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPB P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6706 14.5109 BLBplus -135.21, 165.17 64.35, 37.85 -90.15, 169.17 53.82, 91.67 84.59, 7.68 out-out out 13.7558 Saltbr-out 13.8881 HRD-in -70.65, -63.17 87.36, -17.28 out-out-out SNCooo out-out ActLoopNT-out 7.5923 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -97.44, -17.16 APE9-dihe-in -126.66, 129.43 APE8-dihe-in -78.52, 67.74 APE8-rot-na 34.72 APE67-dihe-in -76.32, -3.64 -51.52, -45.13 APE12-dist-na 17.4376 APE11-dist-na 15.2142 APE10-dist-na 12.2746 APE9-dist-in 7.6166 T790M,V948R None None XRAY 2.16 0.214 0.247 B 331.0 308.0 0 30 30 0 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPD P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.766 14.6606 BLBplus -135.69, 167.35 65.6, 33.96 -89.97, 168.72 55.6, 87.2 84.96, 9.82 out-out out 13.5259 Saltbr-out 11.2829 HRD-in -71.06, -65.03 87.13, -14.24 out-out-none SNCoon out-none ActLoopNT-out 8.0039 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.01 APE8-dihe-in -77.89, 69.26 APE8-rot-na 33.29 APE67-dihe-in -74.9, -2.69 -52.27, -42.76 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7443 T790M,V948R None None XRAY 2.16 0.214 0.247 D 331.0 294.0 14 30 16 14 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPF P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.9745 14.7024 BLBplus -136.82, 166.82 61.14, 36.57 -93.57, 171.83 53.4, 92.66 83.03, -0.51 out-out out 13.6744 Saltbr-out 11.5698 HRD-in -71.01, -63.71 87.17, -13.68 out-out-none SNCoon out-none ActLoopNT-out 9.118 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 127.33 APE8-dihe-in -78.62, 69.48 APE8-rot-na 32.72 APE67-dihe-in -72.69, -4.28 -52.16, -45.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.6211 T790M,V948R None None XRAY 2.16 0.214 0.247 F 331.0 294.0 14 30 16 14 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPC P00533 700 1007 1210.0 JBJ:1101,YY3:1102 Type3,Type1 Inactive DFGin 4.791 14.4893 BLBplus -135.14, 166.93 58.75, 39.54 -88.72, 165.62 50.16, 82.07 80.91, 11.4 out-out out 13.2148 Saltbr-out 10.0097 HRD-in -71.03, -65.61 90.59, -16.24 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.4 APE8-dihe-in -78.08, 71.31 APE8-rot-na 31.49 APE67-dihe-in -74.31, -4.1 -55.2, -45.03 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7338 T790M,V948R None None XRAY 2.16 0.214 0.247 C 331.0 292.0 16 30 14 16 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPE P00533 700 1007 1210.0 JBJ:1101,YY3:1102 Type3,Type1 Inactive DFGin 5.0169 14.7096 BLBplus -135.91, 163.38 57.21, 38.2 -87.34, 167.11 54.31, 95.16 79.16, 16.43 out-out out 13.5808 Saltbr-out 11.0085 HRD-in -68.91, -62.25 86.58, -12.8 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 129.81 APE8-dihe-in -81.71, 69.65 APE8-rot-na 31.8 APE67-dihe-in -77.02, -5.14 -52.47, -41.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4598 T790M,V948R None None XRAY 2.16 0.214 0.247 E 331.0 287.0 16 30 14 16 [[712, 970]] 1.0 7jxp TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXP — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7JXPA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXPA P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.7467 14.6167 BLBplus -136.18, 166.76 64.66, 34.04 -92.53, 168.9 56.02, 85.41 85.63, 11.86 out-out out 13.9879 Saltbr-out 14.3068 HRD-in -74.54, -64.28 89.28, -17.63 out-out-out SNCooo out-out ActLoopNT-out 7.5088 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -97.63, -15.8 APE9-dihe-in -113.05, 126.54 APE8-dihe-in -83.29, 68.9 APE8-rot-na 33.94 APE67-dihe-in -74.36, -3.96 -52.3, -47.62 APE12-dist-na 17.0956 APE11-dist-na 14.9557 APE10-dist-na 11.6928 APE9-dist-in 7.4058 T790M,V948R None None XRAY 2.16 0.214 0.247 A 331.0 308.0 0 30 30 0 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPB P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.6706 14.5109 BLBplus -135.21, 165.17 64.35, 37.85 -90.15, 169.17 53.82, 91.67 84.59, 7.68 out-out out 13.7558 Saltbr-out 13.8881 HRD-in -70.65, -63.17 87.36, -17.28 out-out-out SNCooo out-out ActLoopNT-out 7.5923 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -97.44, -17.16 APE9-dihe-in -126.66, 129.43 APE8-dihe-in -78.52, 67.74 APE8-rot-na 34.72 APE67-dihe-in -76.32, -3.64 -51.52, -45.13 APE12-dist-na 17.4376 APE11-dist-na 15.2142 APE10-dist-na 12.2746 APE9-dist-in 7.6166 T790M,V948R None None XRAY 2.16 0.214 0.247 B 331.0 308.0 0 30 30 0 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPD P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.766 14.6606 BLBplus -135.69, 167.35 65.6, 33.96 -89.97, 168.72 55.6, 87.2 84.96, 9.82 out-out out 13.5259 Saltbr-out 11.2829 HRD-in -71.06, -65.03 87.13, -14.24 out-out-none SNCoon out-none ActLoopNT-out 8.0039 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 134.01 APE8-dihe-in -77.89, 69.26 APE8-rot-na 33.29 APE67-dihe-in -74.9, -2.69 -52.27, -42.76 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7443 T790M,V948R None None XRAY 2.16 0.214 0.247 D 331.0 294.0 14 30 16 14 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPF P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.9745 14.7024 BLBplus -136.82, 166.82 61.14, 36.57 -93.57, 171.83 53.4, 92.66 83.03, -0.51 out-out out 13.6744 Saltbr-out 11.5698 HRD-in -71.01, -63.71 87.17, -13.68 out-out-none SNCoon out-none ActLoopNT-out 9.118 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 127.33 APE8-dihe-in -78.62, 69.48 APE8-rot-na 32.72 APE67-dihe-in -72.69, -4.28 -52.16, -45.07 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.6211 T790M,V948R None None XRAY 2.16 0.214 0.247 F 331.0 294.0 14 30 16 14 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPC P00533 700 1007 1210.0 JBJ:1101,YY3:1102 Type3,Type1 Inactive DFGin 4.791 14.4893 BLBplus -135.14, 166.93 58.75, 39.54 -88.72, 165.62 50.16, 82.07 80.91, 11.4 out-out out 13.2148 Saltbr-out 10.0097 HRD-in -71.03, -65.61 90.59, -16.24 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 133.4 APE8-dihe-in -78.08, 71.31 APE8-rot-na 31.49 APE67-dihe-in -74.31, -4.1 -55.2, -45.03 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7338 T790M,V948R None None XRAY 2.16 0.214 0.247 C 331.0 292.0 16 30 14 16 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXPE P00533 700 1007 1210.0 JBJ:1101,YY3:1102 Type3,Type1 Inactive DFGin 5.0169 14.7096 BLBplus -135.91, 163.38 57.21, 38.2 -87.34, 167.11 54.31, 95.16 79.16, 16.43 out-out out 13.5808 Saltbr-out 11.0085 HRD-in -68.91, -62.25 86.58, -12.8 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 129.81 APE8-dihe-in -81.71, 69.65 APE8-rot-na 31.8 APE67-dihe-in -77.02, -5.14 -52.47, -41.73 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4598 T790M,V948R None None XRAY 2.16 0.214 0.247 E 331.0 287.0 16 30 14 16 [[712, 970]] 1.0 7jxp Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXP — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name