PDB: 7JXM — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 7JXMB
DFGin BLBtrans 1 25.0% 7JXMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXMC P00533 702 1006 1210.0 ANP:1101 ATPlike Inactive DFGin 4.2828 13.994 BLBplus -133.09, 168.24 59.36, 33.1 -80.78, 143.72 58.15, 87.09 66.36, 74.02 out-out out 13.9625 Saltbr-out 13.1185 HRD-in -67.9, -61.75 83.53, -6.82 out-out-none SNCoon out-none ActLoopNT-out 9.0085 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 139.47 APE8-dihe-in -77.6, 66.96 APE8-rot-na 35.92 APE67-dihe-in -75.2, -5.27 -47.14, -42.38 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.517 T790M,V948R None None XRAY 2.192 0.228 0.271 C 331.0 285.0 20 30 15 15 [[712, 970]] 1.0 7jxm TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMD P00533 700 1007 1210.0 ANP:1101,9LL:1103 ATPlike,Type3 Inactive DFGin 4.9516 14.3368 BLBplus -135.28, 170.25 61.86, 31.57 -85.27, 155.14 53.77, 85.22 78.23, 19.31 out-out out 13.0485 Saltbr-out 11.8943 HRD-in -66.52, -63.02 84.71, -6.37 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 136.04 APE8-dihe-in -80.42, 66.88 APE8-rot-na 32.97 APE67-dihe-in -76.05, -3.45 -51.47, -42.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.762 T790M,V948R None None XRAY 2.192 0.228 0.271 D 331.0 291.0 17 30 13 17 [[712, 970]] 1.0 7jxm TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMB P00533 701 1012 1210.0 YY3:1101,9LL:1102 Type1,Type3 Inactive DFGin 5.1552 14.6479 BLBplus -133.95, 169.04 59.67, 39.65 -96.16, 166.65 49.37, 86.58 68.24, 16.57 out-out out 13.1662 Saltbr-out 10.454 HRD-in -67.1, -62.37 83.6, -7.78 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 126.13 APE8-dihe-in -90.39, 74.47 APE8-rot-na 39.92 APE67-dihe-in -71.29, -11.25 -51.45, -39.54 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7793 T790M,V948R None None XRAY 2.192 0.228 0.271 B 331.0 296.0 16 30 14 16 [[712, 970]] 1.0 7jxm TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMA P00533 700 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 4.9584 16.1723 BLBtrans -132.35, 172.29 62.1, 35.15 -75.21, 146.26 142.71, 77.54 74.06, -11.26 out-out out 13.8943 Saltbr-out 13.3399 HRD-in -71.64, -59.02 81.62, -5.92 out-out-none SNCoon out-none ActLoopNT-out 8.0723 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 131.88 APE8-dihe-in -79.6, 70.11 APE8-rot-na 34.33 APE67-dihe-in -76.06, -4.61 -47.57, -45.29 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5303 T790M,V948R None None XRAY 2.192 0.228 0.271 A 331.0 287.0 18 30 16 14 [[712, 970]] 1.0 7jxm TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXM — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 7JXMB
DFGin BLBtrans 1 25.0% 7JXMA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXMC P00533 702 1006 1210.0 ANP:1101 ATPlike Inactive DFGin 4.2828 13.994 BLBplus -133.09, 168.24 59.36, 33.1 -80.78, 143.72 58.15, 87.09 66.36, 74.02 out-out out 13.9625 Saltbr-out 13.1185 HRD-in -67.9, -61.75 83.53, -6.82 out-out-none SNCoon out-none ActLoopNT-out 9.0085 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 139.47 APE8-dihe-in -77.6, 66.96 APE8-rot-na 35.92 APE67-dihe-in -75.2, -5.27 -47.14, -42.38 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.517 T790M,V948R None None XRAY 2.192 0.228 0.271 C 331.0 285.0 20 30 15 15 [[712, 970]] 1.0 7jxm Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMD P00533 700 1007 1210.0 ANP:1101,9LL:1103 ATPlike,Type3 Inactive DFGin 4.9516 14.3368 BLBplus -135.28, 170.25 61.86, 31.57 -85.27, 155.14 53.77, 85.22 78.23, 19.31 out-out out 13.0485 Saltbr-out 11.8943 HRD-in -66.52, -63.02 84.71, -6.37 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 136.04 APE8-dihe-in -80.42, 66.88 APE8-rot-na 32.97 APE67-dihe-in -76.05, -3.45 -51.47, -42.13 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.762 T790M,V948R None None XRAY 2.192 0.228 0.271 D 331.0 291.0 17 30 13 17 [[712, 970]] 1.0 7jxm Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMB P00533 701 1012 1210.0 YY3:1101,9LL:1102 Type1,Type3 Inactive DFGin 5.1552 14.6479 BLBplus -133.95, 169.04 59.67, 39.65 -96.16, 166.65 49.37, 86.58 68.24, 16.57 out-out out 13.1662 Saltbr-out 10.454 HRD-in -67.1, -62.37 83.6, -7.78 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 126.13 APE8-dihe-in -90.39, 74.47 APE8-rot-na 39.92 APE67-dihe-in -71.29, -11.25 -51.45, -39.54 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.7793 T790M,V948R None None XRAY 2.192 0.228 0.271 B 331.0 296.0 16 30 14 16 [[712, 970]] 1.0 7jxm Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXMA P00533 700 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 4.9584 16.1723 BLBtrans -132.35, 172.29 62.1, 35.15 -75.21, 146.26 142.71, 77.54 74.06, -11.26 out-out out 13.8943 Saltbr-out 13.3399 HRD-in -71.64, -59.02 81.62, -5.92 out-out-none SNCoon out-none ActLoopNT-out 8.0723 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 131.88 APE8-dihe-in -79.6, 70.11 APE8-rot-na 34.33 APE67-dihe-in -76.06, -4.61 -47.57, -45.29 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5303 T790M,V948R None None XRAY 2.192 0.228 0.271 A 331.0 287.0 18 30 16 14 [[712, 970]] 1.0 7jxm Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXM — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name