PDB: 7JXK — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7JXKD

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXKB P00533 700 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 4.788 14.304 BLBplus -133.99, 169.66 58.32, 39.23 -93.88, 160.42 49.41, 87.38 74.89, 999.0 out-out out 13.49 Saltbr-out 12.394 HRD-in -66.37, -58.14 81.2, -5.32 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.52 APE8-dihe-in -80.54, 72.01 APE8-rot-na 30.24 APE67-dihe-in -73.85, -4.26 -53.45, -45.93 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.541 T790M,V948R None None XRAY 3.1 0.223 0.261 B 331 290 18 0 0 18 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKD P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.861 14.45 BLBplus -134.29, 170.65 60.11, 37.92 -95.07, 160.21 48.8, 86.41 74.63, 26.88 out-out out 13.457 Saltbr-out 11.763 HRD-in -66.46, -59.56 80.54, -6.1 out-out-none SNCoon out-none ActLoopNT-out 8.903 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.41 APE8-dihe-in -81.29, 71.57 APE8-rot-na 30.4 APE67-dihe-in -73.66, -4.05 -53.54, -44.77 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.472 T790M,V948R None None XRAY 3.1 0.223 0.261 D 331 294 14 0 0 14 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKA P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.862 14.824 BLBplus -134.12, 169.24 58.43, 39.5 -93.7, 161.51 49.25, 87.25 75.0, 16.23 out-out out 13.778 Saltbr-out 10.461 HRD-in -66.55, -57.53 81.35, -6.11 out-out-none SNCoon out-none ActLoopNT-out 8.816 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.68 APE8-dihe-in -81.09, 70.58 APE8-rot-na 30.58 APE67-dihe-in -73.21, -4.24 -54.1, -46.78 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.489 T790M,V948R None None XRAY 3.1 0.223 0.261 A 331 293 15 0 0 15 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKC P00533 701 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.503 14.594 BLBplus -134.13, 170.52 59.34, 39.88 -92.58, 159.61 51.08, 87.14 75.55, 20.71 out-out out 13.608 Saltbr-out 11.925 HRD-in -66.31, -58.5 79.98, -6.68 out-out-none SNCoon out-none ActLoopNT-out 8.44 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.55 APE8-dihe-in -81.28, 70.99 APE8-rot-na 30.58 APE67-dihe-in -73.05, -5.14 -53.98, -44.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.444 T790M,V948R None None XRAY 3.1 0.223 0.261 C 331 292 15 0 0 15 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKE P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.893 14.488 BLBplus -134.7, 170.02 59.73, 38.84 -95.72, 161.23 49.85, 87.39 75.41, 21.47 out-out out 13.509 Saltbr-out 11.783 HRD-in -66.69, -59.11 80.54, -6.15 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.43 APE8-dihe-in -79.83, 71.88 APE8-rot-na 29.74 APE67-dihe-in -73.96, -4.52 -53.36, -45.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.534 T790M,V948R None None XRAY 3.1 0.223 0.261 E 331 287 16 0 0 16 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKF P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.872 14.387 BLBplus -134.77, 169.91 59.08, 39.36 -94.94, 160.87 49.89, 87.34 75.14, 17.06 out-out out 13.528 Saltbr-out 12.787 HRD-in -66.88, -58.5 80.33, -5.79 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.79 APE8-dihe-in -81.39, 71.1 APE8-rot-na 29.52 APE67-dihe-in -73.84, -5.2 -54.64, -45.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.478 T790M,V948R None None XRAY 3.1 0.223 0.261 F 331 292 16 0 0 16 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXK — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7JXKD

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXKB P00533 700 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 4.788 14.304 BLBplus -133.99, 169.66 58.32, 39.23 -93.88, 160.42 49.41, 87.38 74.89, 999.0 out-out out 13.49 Saltbr-out 12.394 HRD-in -66.37, -58.14 81.2, -5.32 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.52 APE8-dihe-in -80.54, 72.01 APE8-rot-na 30.24 APE67-dihe-in -73.85, -4.26 -53.45, -45.93 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.541 T790M,V948R None None XRAY 3.1 0.223 0.261 B 331 290 18 0 0 18 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKD P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.861 14.45 BLBplus -134.29, 170.65 60.11, 37.92 -95.07, 160.21 48.8, 86.41 74.63, 26.88 out-out out 13.457 Saltbr-out 11.763 HRD-in -66.46, -59.56 80.54, -6.1 out-out-none SNCoon out-none ActLoopNT-out 8.903 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.41 APE8-dihe-in -81.29, 71.57 APE8-rot-na 30.4 APE67-dihe-in -73.66, -4.05 -53.54, -44.77 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.472 T790M,V948R None None XRAY 3.1 0.223 0.261 D 331 294 14 0 0 14 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKA P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.862 14.824 BLBplus -134.12, 169.24 58.43, 39.5 -93.7, 161.51 49.25, 87.25 75.0, 16.23 out-out out 13.778 Saltbr-out 10.461 HRD-in -66.55, -57.53 81.35, -6.11 out-out-none SNCoon out-none ActLoopNT-out 8.816 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.68 APE8-dihe-in -81.09, 70.58 APE8-rot-na 30.58 APE67-dihe-in -73.21, -4.24 -54.1, -46.78 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.489 T790M,V948R None None XRAY 3.1 0.223 0.261 A 331 293 15 0 0 15 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKC P00533 701 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.503 14.594 BLBplus -134.13, 170.52 59.34, 39.88 -92.58, 159.61 51.08, 87.14 75.55, 20.71 out-out out 13.608 Saltbr-out 11.925 HRD-in -66.31, -58.5 79.98, -6.68 out-out-none SNCoon out-none ActLoopNT-out 8.44 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.55 APE8-dihe-in -81.28, 70.99 APE8-rot-na 30.58 APE67-dihe-in -73.05, -5.14 -53.98, -44.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.444 T790M,V948R None None XRAY 3.1 0.223 0.261 C 331 292 15 0 0 15 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKE P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.893 14.488 BLBplus -134.7, 170.02 59.73, 38.84 -95.72, 161.23 49.85, 87.39 75.41, 21.47 out-out out 13.509 Saltbr-out 11.783 HRD-in -66.69, -59.11 80.54, -6.15 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.43 APE8-dihe-in -79.83, 71.88 APE8-rot-na 29.74 APE67-dihe-in -73.96, -4.52 -53.36, -45.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.534 T790M,V948R None None XRAY 3.1 0.223 0.261 E 331 287 16 0 0 16 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKF P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.872 14.387 BLBplus -134.77, 169.91 59.08, 39.36 -94.94, 160.87 49.89, 87.34 75.14, 17.06 out-out out 13.528 Saltbr-out 12.787 HRD-in -66.88, -58.5 80.33, -5.79 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.79 APE8-dihe-in -81.39, 71.1 APE8-rot-na 29.52 APE67-dihe-in -73.84, -5.2 -54.64, -45.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.478 T790M,V948R None None XRAY 3.1 0.223 0.261 F 331 292 16 0 0 16 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXK — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name