PDB: 7JXK — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7JXKD

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Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXKB P00533 700 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 4.788 14.3042 BLBplus -133.99, 169.66 58.32, 39.23 -93.88, 160.42 49.41, 87.38 74.89, 999.0 out-out out 13.4903 Saltbr-out 12.3941 HRD-in -66.37, -58.14 81.2, -5.32 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.52 APE8-dihe-in -80.54, 72.01 APE8-rot-na 30.24 APE67-dihe-in -73.85, -4.26 -53.45, -45.93 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5412 T790M,V948R None None XRAY 3.1 0.223 0.261 B 331.0 290.0 18 30 12 18 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKD P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.8614 14.45 BLBplus -134.29, 170.65 60.11, 37.92 -95.07, 160.21 48.8, 86.41 74.63, 26.88 out-out out 13.4574 Saltbr-out 11.7626 HRD-in -66.46, -59.56 80.54, -6.1 out-out-none SNCoon out-none ActLoopNT-out 8.9029 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.41 APE8-dihe-in -81.29, 71.57 APE8-rot-na 30.4 APE67-dihe-in -73.66, -4.05 -53.54, -44.77 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4718 T790M,V948R None None XRAY 3.1 0.223 0.261 D 331.0 294.0 14 30 16 14 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKA P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.8625 14.8244 BLBplus -134.12, 169.24 58.43, 39.5 -93.7, 161.51 49.25, 87.25 75.0, 16.23 out-out out 13.7778 Saltbr-out 10.4611 HRD-in -66.55, -57.53 81.35, -6.11 out-out-none SNCoon out-none ActLoopNT-out 8.8163 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.68 APE8-dihe-in -81.09, 70.58 APE8-rot-na 30.58 APE67-dihe-in -73.21, -4.24 -54.1, -46.78 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4886 T790M,V948R None None XRAY 3.1 0.223 0.261 A 331.0 293.0 15 30 15 15 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKC P00533 701 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.5028 14.594 BLBplus -134.13, 170.52 59.34, 39.88 -92.58, 159.61 51.08, 87.14 75.55, 20.71 out-out out 13.6078 Saltbr-out 11.9254 HRD-in -66.31, -58.5 79.98, -6.68 out-out-none SNCoon out-none ActLoopNT-out 8.4402 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.55 APE8-dihe-in -81.28, 70.99 APE8-rot-na 30.58 APE67-dihe-in -73.05, -5.14 -53.98, -44.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4444 T790M,V948R None None XRAY 3.1 0.223 0.261 C 331.0 292.0 15 30 15 15 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKE P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.8927 14.4875 BLBplus -134.7, 170.02 59.73, 38.84 -95.72, 161.23 49.85, 87.39 75.41, 21.47 out-out out 13.5094 Saltbr-out 11.7833 HRD-in -66.69, -59.11 80.54, -6.15 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.43 APE8-dihe-in -79.83, 71.88 APE8-rot-na 29.74 APE67-dihe-in -73.96, -4.52 -53.36, -45.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5344 T790M,V948R None None XRAY 3.1 0.223 0.261 E 331.0 287.0 16 30 14 16 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKF P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.8717 14.3868 BLBplus -134.77, 169.91 59.08, 39.36 -94.94, 160.87 49.89, 87.34 75.14, 17.06 out-out out 13.5278 Saltbr-out 12.787 HRD-in -66.88, -58.5 80.33, -5.79 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.79 APE8-dihe-in -81.39, 71.1 APE8-rot-na 29.52 APE67-dihe-in -73.84, -5.2 -54.64, -45.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4784 T790M,V948R None None XRAY 3.1 0.223 0.261 F 331.0 292.0 16 30 14 16 [[712, 970]] 1.0 7jxk TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXK — TYR EGFR_HUMAN

Total number of chains: 6
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 6 100.0% 7JXKD

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 7JXKB P00533 700 1007 1210.0 ANP:1101 ATPlike Inactive DFGin 4.788 14.3042 BLBplus -133.99, 169.66 58.32, 39.23 -93.88, 160.42 49.41, 87.38 74.89, 999.0 out-out out 13.4903 Saltbr-out 12.3941 HRD-in -66.37, -58.14 81.2, -5.32 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.52 APE8-dihe-in -80.54, 72.01 APE8-rot-na 30.24 APE67-dihe-in -73.85, -4.26 -53.45, -45.93 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5412 T790M,V948R None None XRAY 3.1 0.223 0.261 B 331.0 290.0 18 30 12 18 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKD P00533 700 1007 1210.0 ANP:1101,JBJ:1103 ATPlike,Type3 Inactive DFGin 4.8614 14.45 BLBplus -134.29, 170.65 60.11, 37.92 -95.07, 160.21 48.8, 86.41 74.63, 26.88 out-out out 13.4574 Saltbr-out 11.7626 HRD-in -66.46, -59.56 80.54, -6.1 out-out-none SNCoon out-none ActLoopNT-out 8.9029 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.41 APE8-dihe-in -81.29, 71.57 APE8-rot-na 30.4 APE67-dihe-in -73.66, -4.05 -53.54, -44.77 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4718 T790M,V948R None None XRAY 3.1 0.223 0.261 D 331.0 294.0 14 30 16 14 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKA P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.8625 14.8244 BLBplus -134.12, 169.24 58.43, 39.5 -93.7, 161.51 49.25, 87.25 75.0, 16.23 out-out out 13.7778 Saltbr-out 10.4611 HRD-in -66.55, -57.53 81.35, -6.11 out-out-none SNCoon out-none ActLoopNT-out 8.8163 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.68 APE8-dihe-in -81.09, 70.58 APE8-rot-na 30.58 APE67-dihe-in -73.21, -4.24 -54.1, -46.78 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4886 T790M,V948R None None XRAY 3.1 0.223 0.261 A 331.0 293.0 15 30 15 15 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKC P00533 701 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.5028 14.594 BLBplus -134.13, 170.52 59.34, 39.88 -92.58, 159.61 51.08, 87.14 75.55, 20.71 out-out out 13.6078 Saltbr-out 11.9254 HRD-in -66.31, -58.5 79.98, -6.68 out-out-none SNCoon out-none ActLoopNT-out 8.4402 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.55 APE8-dihe-in -81.28, 70.99 APE8-rot-na 30.58 APE67-dihe-in -73.05, -5.14 -53.98, -44.81 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4444 T790M,V948R None None XRAY 3.1 0.223 0.261 C 331.0 292.0 15 30 15 15 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKE P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.8927 14.4875 BLBplus -134.7, 170.02 59.73, 38.84 -95.72, 161.23 49.85, 87.39 75.41, 21.47 out-out out 13.5094 Saltbr-out 11.7833 HRD-in -66.69, -59.11 80.54, -6.15 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 138.43 APE8-dihe-in -79.83, 71.88 APE8-rot-na 29.74 APE67-dihe-in -73.96, -4.52 -53.36, -45.18 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.5344 T790M,V948R None None XRAY 3.1 0.223 0.261 E 331.0 287.0 16 30 14 16 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 7JXKF P00533 700 1007 1210.0 8BS:1101,JBJ:1102 Type1,Type3 Inactive DFGin 4.8717 14.3868 BLBplus -134.77, 169.91 59.08, 39.36 -94.94, 160.87 49.89, 87.34 75.14, 17.06 out-out out 13.5278 Saltbr-out 12.787 HRD-in -66.88, -58.5 80.33, -5.79 out-none-none SNConn none-none ActLoopNT-none 999.0 ActLoopCT-none TYR APEdihe_nniai APEdist_aaai APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 137.79 APE8-dihe-in -81.39, 71.1 APE8-rot-na 29.52 APE67-dihe-in -73.84, -5.2 -54.64, -45.48 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-in 7.4784 T790M,V948R None None XRAY 3.1 0.223 0.261 F 331.0 292.0 16 30 14 16 [[712, 970]] 1.0 7jxk Homo sapiens TYR_EGFR_HUMAN TYR 6.3e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 7JXK — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative

Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ
DFG-Asp
φ,ψ
DFG-Phe
φ,ψ
DFG-Phe
χ1,χ2
DFG-Gly
φ,ψ
ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name