PDB: 7AX4 — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 7AX4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 7AX4A P29597 579 868 1187.0 NM7:2000 Type1 Pseudo DFGin 7.5069 12.8047 None -76.81, 166.44 -58.43, 152.23 -70.05, -8.8 24.77, 146.14 76.34, -154.15 in-na in 9.5557 Saltbr-na 999.0 HRD-in -86.69, -61.89 82.12, 4.68 na-out-out SNCaoo out-out ActLoopNT-out 8.2321 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -63.65, -45.17 APE9-dihe-out -58.59, -27.02 APE8-dihe-out -78.56, -9.63 APE8-rot-na 222.71 APE67-dihe-out -95.98, 6.87 -68.07, 131.63 APE12-dist-na 9.6622 APE11-dist-na 12.2836 APE10-dist-na 16.4637 APE9-dist-out 11.658 None None None XRAY 2.12 0.186 0.229 A 295.0 261.0 29 24 24 0 [[589, 868], [897, 1171]] 2.0 7ax4 TYR_TYK2-1_HUMAN TYR 4.1e-60 209.3 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7AX4B P29597 579 868 1187.0 NM7:2000 Type1 Pseudo DFGin 7.4876 12.7756 None -74.88, 165.0 -57.44, 152.12 -71.28, -8.27 25.03, 145.7 75.91, -154.77 in-na in 9.4964 Saltbr-na 999.0 HRD-in -85.26, -61.54 83.16, 3.63 na-out-out SNCaoo out-out ActLoopNT-out 8.3251 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -63.51, -41.43 APE9-dihe-out -63.74, -26.18 APE8-dihe-out -77.76, -6.82 APE8-rot-na 221.04 APE67-dihe-out -90.97, 8.23 -71.21, 136.1 APE12-dist-na 9.8072 APE11-dist-na 12.3205 APE10-dist-na 16.5418 APE9-dist-out 11.7928 None None None XRAY 2.12 0.186 0.229 B 295.0 261.0 29 24 24 0 [[589, 868], [897, 1171]] 2.0 7ax4 TYR_TYK2-1_HUMAN TYR 4.1e-60 209.3 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 7AX4 — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin None 2 100.0% 7AX4A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-1 TYK2_HUMAN 7AX4A P29597 579 868 1187.0 NM7:2000 Type1 Pseudo DFGin 7.5069 12.8047 None -76.81, 166.44 -58.43, 152.23 -70.05, -8.8 24.77, 146.14 76.34, -154.15 in-na in 9.5557 Saltbr-na 999.0 HRD-in -86.69, -61.89 82.12, 4.68 na-out-out SNCaoo out-out ActLoopNT-out 8.2321 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -63.65, -45.17 APE9-dihe-out -58.59, -27.02 APE8-dihe-out -78.56, -9.63 APE8-rot-na 222.71 APE67-dihe-out -95.98, 6.87 -68.07, 131.63 APE12-dist-na 9.6622 APE11-dist-na 12.2836 APE10-dist-na 16.4637 APE9-dist-out 11.658 None None None XRAY 2.12 0.186 0.229 A 295.0 261.0 29 24 24 0 [[589, 868], [897, 1171]] 2.0 7ax4 Homo sapiens TYR_TYK2-1_HUMAN TYR 4.1e-60 209.3 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-1 TYK2_HUMAN 7AX4B P29597 579 868 1187.0 NM7:2000 Type1 Pseudo DFGin 7.4876 12.7756 None -74.88, 165.0 -57.44, 152.12 -71.28, -8.27 25.03, 145.7 75.91, -154.77 in-na in 9.4964 Saltbr-na 999.0 HRD-in -85.26, -61.54 83.16, 3.63 na-out-out SNCaoo out-out ActLoopNT-out 8.3251 ActLoopCT-out TYR APEdihe_oooao APEdist_aaao APE10-dihe-out -63.51, -41.43 APE9-dihe-out -63.74, -26.18 APE8-dihe-out -77.76, -6.82 APE8-rot-na 221.04 APE67-dihe-out -90.97, 8.23 -71.21, 136.1 APE12-dist-na 9.8072 APE11-dist-na 12.3205 APE10-dist-na 16.5418 APE9-dist-out 11.7928 None None None XRAY 2.12 0.186 0.229 B 295.0 261.0 29 24 24 0 [[589, 868], [897, 1171]] 2.0 7ax4 Homo sapiens TYR_TYK2-1_HUMAN TYR 4.1e-60 209.3 2.0 260.0 259.0 758 759 760 762 764 642 658 662 731 733 732 734.0 796 782 777 776 775 774 773 772 771 688 Non-receptor tyrosine-protein kinase TYK2

PDB: 7AX4 — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name