PDB: 6X8F — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6X8FC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-2 TYK2_HUMAN 6X8FA P29597 889 1178 1187.0 UWP:4001 Type1 Inactive DFGin 6.3676 13.4432 ABAminus -95.56, -18.62 -136.08, 142.25 -132.97, 38.39 300.79, 80.69 -60.74, -30.23 in-in in 8.5896 Saltbr-in 2.814 HRD-in -80.09, -50.24 67.91, 4.2 in-in-out SNCiio in-out ActLoopNT-in 2.8129 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -85.77, 10.94 APE9-dihe-in -74.28, 130.62 APE8-dihe-in -82.04, 69.42 APE8-rot-na 28.67 APE67-dihe-in -81.13, -2.61 -51.22, -29.34 APE12-dist-na 9.813 APE11-dist-na 12.6751 APE10-dist-na 9.1932 APE9-dist-in 6.5253 C936A,Q969A,E971A,K972A,A1016S,C1142A PTR1054 PTR1054 XRAY 2.15 0.208 0.255 A 318.0 283.0 7 31 31 0 [[589, 868], [897, 1171]] 2.0 6x8f TYR_TYK2-2_HUMAN TYR 5.1e-82 281.0 2.0 260.0 259.0 1040 1041 1042 1044 1046 930 947 951 1020 1022 1021 1023.0 1083 1071 1066 1065 1064 1063 1062 1061 1060 979 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6X8FC P29597 889 1178 1187.0 UWP:4000 Type1 Inactive DFGin 6.4114 13.4672 ABAminus -95.34, -17.32 -136.72, 141.32 -133.98, 37.29 300.65, 80.99 -60.17, -32.21 in-in in 8.4894 Saltbr-in 2.6961 HRD-in -78.97, -50.37 67.86, 4.05 in-in-out SNCiio in-out ActLoopNT-in 2.8085 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -92.16, 9.73 APE9-dihe-in -74.69, 130.77 APE8-dihe-in -82.29, 70.3 APE8-rot-na 28.25 APE67-dihe-in -80.62, -2.35 -52.14, -29.87 APE12-dist-na 10.8918 APE11-dist-na 12.8588 APE10-dist-na 9.1891 APE9-dist-in 6.55 C936A,Q969A,E971A,K972A,A1016S,C1142A PTR1054 PTR1054 XRAY 2.15 0.208 0.255 C 318.0 290.0 0 31 31 0 [[589, 868], [897, 1171]] 2.0 6x8f TYR_TYK2-2_HUMAN TYR 5.1e-82 281.0 2.0 260.0 259.0 1040 1041 1042 1044 1046 930 947 951 1020 1022 1021 1023.0 1083 1071 1066 1065 1064 1063 1062 1061 1060 979 Non-receptor tyrosine-protein kinase TYK2

PDB: 6X8F — TYR TYK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6X8FC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR TYK2-2 TYK2_HUMAN 6X8FA P29597 889 1178 1187.0 UWP:4001 Type1 Inactive DFGin 6.3676 13.4432 ABAminus -95.56, -18.62 -136.08, 142.25 -132.97, 38.39 300.79, 80.69 -60.74, -30.23 in-in in 8.5896 Saltbr-in 2.814 HRD-in -80.09, -50.24 67.91, 4.2 in-in-out SNCiio in-out ActLoopNT-in 2.8129 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -85.77, 10.94 APE9-dihe-in -74.28, 130.62 APE8-dihe-in -82.04, 69.42 APE8-rot-na 28.67 APE67-dihe-in -81.13, -2.61 -51.22, -29.34 APE12-dist-na 9.813 APE11-dist-na 12.6751 APE10-dist-na 9.1932 APE9-dist-in 6.5253 C936A,Q969A,E971A,K972A,A1016S,C1142A PTR1054 PTR1054 XRAY 2.15 0.208 0.255 A 318.0 283.0 7 31 31 0 [[589, 868], [897, 1171]] 2.0 6x8f Homo sapiens TYR_TYK2-2_HUMAN TYR 5.1e-82 281.0 2.0 260.0 259.0 1040 1041 1042 1044 1046 930 947 951 1020 1022 1021 1023.0 1083 1071 1066 1065 1064 1063 1062 1061 1060 979 Non-receptor tyrosine-protein kinase TYK2
TYR TYK2-2 TYK2_HUMAN 6X8FC P29597 889 1178 1187.0 UWP:4000 Type1 Inactive DFGin 6.4114 13.4672 ABAminus -95.34, -17.32 -136.72, 141.32 -133.98, 37.29 300.65, 80.99 -60.17, -32.21 in-in in 8.4894 Saltbr-in 2.6961 HRD-in -78.97, -50.37 67.86, 4.05 in-in-out SNCiio in-out ActLoopNT-in 2.8085 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -92.16, 9.73 APE9-dihe-in -74.69, 130.77 APE8-dihe-in -82.29, 70.3 APE8-rot-na 28.25 APE67-dihe-in -80.62, -2.35 -52.14, -29.87 APE12-dist-na 10.8918 APE11-dist-na 12.8588 APE10-dist-na 9.1891 APE9-dist-in 6.55 C936A,Q969A,E971A,K972A,A1016S,C1142A PTR1054 PTR1054 XRAY 2.15 0.208 0.255 C 318.0 290.0 0 31 31 0 [[589, 868], [897, 1171]] 2.0 6x8f Homo sapiens TYR_TYK2-2_HUMAN TYR 5.1e-82 281.0 2.0 260.0 259.0 1040 1041 1042 1044 1046 930 947 951 1020 1022 1021 1023.0 1083 1071 1066 1065 1064 1063 1062 1061 1060 979 Non-receptor tyrosine-protein kinase TYK2

PDB: 6X8F — TYR TYK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name