PDB: 6WAK — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 6WAKA
DFGin BLBtrans 1 25.0% 6WAKB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6WAKA P00533 702 1013 1210.0 ANP:1101 ATPlike Inactive DFGin 3.68 14.038 BLBplus -119.87, 174.58 64.54, 16.96 -69.25, 144.86 73.85, 86.13 77.2, -6.44 out-out out 14.19 Saltbr-out 14.87 HRD-in -68.06, -64.5 89.93, -15.8 out-out-out SNCooo out-out ActLoopNT-out 6.056 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -95.75, -0.13 APE9-dihe-in -104.56, 101.78 APE8-dihe-in -62.85, 69.07 APE8-rot-na 27.65 APE67-dihe-in -73.63, -8.28 -54.79, -35.95 APE12-dist-na 999.0 APE11-dist-na 15.624 APE10-dist-na 11.34 APE9-dist-in 7.772 T790M,V948R None None XRAY 2.4 0.219 0.23 A 328 297 10 0 0 10 [[712, 970]] 1.0 6wak TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKD P00533 701 1014 1210.0 ANP:1101 ATPlike Inactive DFGin 3.881 14.667 BLBplus -128.56, 164.59 71.9, 35.94 -89.47, 146.64 77.53, 95.38 87.93, -24.37 out-out out 13.753 Saltbr-out 11.845 HRD-in -75.5, -62.2 82.94, 0.35 out-out-out SNCooo out-out ActLoopNT-out 6.735 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 125.69 APE8-dihe-in -82.11, 67.25 APE8-rot-na 35.47 APE67-dihe-in -67.78, -4.44 -51.76, -45.79 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.046 T790M,V948R None None XRAY 2.4 0.219 0.23 D 328 297 17 0 0 14 [[712, 970]] 1.0 6wak TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKC P00533 701 1014 1210.0 TQA:1301 Type1.5_Front Inactive DFGin 4.108 14.307 BLBplus -128.74, 170.35 57.84, 42.31 -80.67, 146.74 56.84, 84.42 73.11, 52.84 out-out out 13.687 Saltbr-out 13.168 HRD-in -69.35, -57.7 81.97, -4.79 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -99.43 APE9-dihe-in -140.88, 118.68 APE8-dihe-in -72.34, 69.57 APE8-rot-na 41.21 APE67-dihe-in -76.32, 0.41 -56.53, -41.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.489 APE9-dist-out 8.042 T790M,V948R None None XRAY 2.4 0.219 0.23 C 328 299 15 0 0 15 [[712, 970]] 1.0 6wak TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKB P00533 701 1020 1210.0 ANP:1101 ATPlike Inactive DFGin 5.177 16.231 BLBtrans -117.23, 173.55 69.28, 15.65 -59.01, 135.6 148.98, 94.52 90.59, -20.79 out-out out 13.949 Saltbr-out 13.543 HRD-in -74.15, -58.44 85.37, -10.97 out-out-none SNCoon out-none ActLoopNT-out 6.481 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -3.86 APE9-dihe-in -108.7, 124.16 APE8-dihe-in -81.26, 64.66 APE8-rot-na 31.83 APE67-dihe-in -71.85, -2.7 -48.1, -51.02 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.366 APE9-dist-in 7.826 T790M,V948R None None XRAY 2.4 0.219 0.23 B 328 316 4 0 0 4 [[712, 970]] 1.0 6wak TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6WAK — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 6WAKA
DFGin BLBtrans 1 25.0% 6WAKB
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6WAKA P00533 702 1013 1210.0 ANP:1101 ATPlike Inactive DFGin 3.68 14.038 BLBplus -119.87, 174.58 64.54, 16.96 -69.25, 144.86 73.85, 86.13 77.2, -6.44 out-out out 14.19 Saltbr-out 14.87 HRD-in -68.06, -64.5 89.93, -15.8 out-out-out SNCooo out-out ActLoopNT-out 6.056 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -95.75, -0.13 APE9-dihe-in -104.56, 101.78 APE8-dihe-in -62.85, 69.07 APE8-rot-na 27.65 APE67-dihe-in -73.63, -8.28 -54.79, -35.95 APE12-dist-na 999.0 APE11-dist-na 15.624 APE10-dist-na 11.34 APE9-dist-in 7.772 T790M,V948R None None XRAY 2.4 0.219 0.23 A 328 297 10 0 0 10 [[712, 970]] 1.0 6wak Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKD P00533 701 1014 1210.0 ANP:1101 ATPlike Inactive DFGin 3.881 14.667 BLBplus -128.56, 164.59 71.9, 35.94 -89.47, 146.64 77.53, 95.38 87.93, -24.37 out-out out 13.753 Saltbr-out 11.845 HRD-in -75.5, -62.2 82.94, 0.35 out-out-out SNCooo out-out ActLoopNT-out 6.735 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 125.69 APE8-dihe-in -82.11, 67.25 APE8-rot-na 35.47 APE67-dihe-in -67.78, -4.44 -51.76, -45.79 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.046 T790M,V948R None None XRAY 2.4 0.219 0.23 D 328 297 17 0 0 14 [[712, 970]] 1.0 6wak Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKC P00533 701 1014 1210.0 TQA:1301 Type1.5_Front Inactive DFGin 4.108 14.307 BLBplus -128.74, 170.35 57.84, 42.31 -80.67, 146.74 56.84, 84.42 73.11, 52.84 out-out out 13.687 Saltbr-out 13.168 HRD-in -69.35, -57.7 81.97, -4.79 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -99.43 APE9-dihe-in -140.88, 118.68 APE8-dihe-in -72.34, 69.57 APE8-rot-na 41.21 APE67-dihe-in -76.32, 0.41 -56.53, -41.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.489 APE9-dist-out 8.042 T790M,V948R None None XRAY 2.4 0.219 0.23 C 328 299 15 0 0 15 [[712, 970]] 1.0 6wak Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKB P00533 701 1020 1210.0 ANP:1101 ATPlike Inactive DFGin 5.177 16.231 BLBtrans -117.23, 173.55 69.28, 15.65 -59.01, 135.6 148.98, 94.52 90.59, -20.79 out-out out 13.949 Saltbr-out 13.543 HRD-in -74.15, -58.44 85.37, -10.97 out-out-none SNCoon out-none ActLoopNT-out 6.481 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -3.86 APE9-dihe-in -108.7, 124.16 APE8-dihe-in -81.26, 64.66 APE8-rot-na 31.83 APE67-dihe-in -71.85, -2.7 -48.1, -51.02 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.366 APE9-dist-in 7.826 T790M,V948R None None XRAY 2.4 0.219 0.23 B 328 316 4 0 0 4 [[712, 970]] 1.0 6wak Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3 259 257 854 855 856 858 860 745 762 766 834 836 835 837 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6WAK — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name