PDB: 6WAK — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 6WAKA
DFGin BLBtrans 1 25.0% 6WAKB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6WAKA P00533 702 1013 1210.0 ANP:1101 ATPlike Inactive DFGin 3.6796 14.038 BLBplus -119.87, 174.58 64.54, 16.96 -69.25, 144.86 73.85, 86.13 77.2, -6.44 out-out out 14.1902 Saltbr-out 14.8704 HRD-in -68.06, -64.5 89.93, -15.8 out-out-out SNCooo out-out ActLoopNT-out 6.0562 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -95.75, -0.13 APE9-dihe-in -104.56, 101.78 APE8-dihe-in -62.85, 69.07 APE8-rot-na 27.65 APE67-dihe-in -73.63, -8.28 -54.79, -35.95 APE12-dist-na 999.0 APE11-dist-na 15.6242 APE10-dist-na 11.3401 APE9-dist-in 7.7723 T790M,V948R None None XRAY 2.4 0.219 0.23 A 328.0 297.0 10 30 20 10 [[712, 970]] 1.0 6wak TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKD P00533 701 1014 1210.0 ANP:1101 ATPlike Inactive DFGin 3.8807 14.6672 BLBplus -128.56, 164.59 71.9, 35.94 -89.47, 146.64 77.53, 95.38 87.93, -24.37 out-out out 13.7529 Saltbr-out 11.845 HRD-in -75.5, -62.2 82.94, 0.35 out-out-out SNCooo out-out ActLoopNT-out 6.735 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 125.69 APE8-dihe-in -82.11, 67.25 APE8-rot-na 35.47 APE67-dihe-in -67.78, -4.44 -51.76, -45.79 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.0459 T790M,V948R None None XRAY 2.4 0.219 0.23 D 328.0 297.0 17 30 16 14 [[712, 970]] 1.0 6wak TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKC P00533 701 1014 1210.0 TQA:1301 Type1.5_Front Inactive DFGin 4.1083 14.3069 BLBplus -128.74, 170.35 57.84, 42.31 -80.67, 146.74 56.84, 84.42 73.11, 52.84 out-out out 13.6867 Saltbr-out 13.1675 HRD-in -69.35, -57.7 81.97, -4.79 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -99.43 APE9-dihe-in -140.88, 118.68 APE8-dihe-in -72.34, 69.57 APE8-rot-na 41.21 APE67-dihe-in -76.32, 0.41 -56.53, -41.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.4889 APE9-dist-out 8.0417 T790M,V948R None None XRAY 2.4 0.219 0.23 C 328.0 299.0 15 30 15 15 [[712, 970]] 1.0 6wak TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKB P00533 701 1020 1210.0 ANP:1101 ATPlike Inactive DFGin 5.1768 16.2307 BLBtrans -117.23, 173.55 69.28, 15.65 -59.01, 135.6 148.98, 94.52 90.59, -20.79 out-out out 13.9491 Saltbr-out 13.5428 HRD-in -74.15, -58.44 85.37, -10.97 out-out-none SNCoon out-none ActLoopNT-out 6.4805 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -3.86 APE9-dihe-in -108.7, 124.16 APE8-dihe-in -81.26, 64.66 APE8-rot-na 31.83 APE67-dihe-in -71.85, -2.7 -48.1, -51.02 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.3657 APE9-dist-in 7.8264 T790M,V948R None None XRAY 2.4 0.219 0.23 B 328.0 316.0 4 30 26 4 [[712, 970]] 1.0 6wak TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6WAK — TYR EGFR_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin BLBplus 3 75.0% 6WAKA
DFGin BLBtrans 1 25.0% 6WAKB
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR EGFR EGFR_HUMAN 6WAKA P00533 702 1013 1210.0 ANP:1101 ATPlike Inactive DFGin 3.6796 14.038 BLBplus -119.87, 174.58 64.54, 16.96 -69.25, 144.86 73.85, 86.13 77.2, -6.44 out-out out 14.1902 Saltbr-out 14.8704 HRD-in -68.06, -64.5 89.93, -15.8 out-out-out SNCooo out-out ActLoopNT-out 6.0562 ActLoopCT-out TYR APEdihe_oiiai APEdist_aaai APE10-dihe-out -95.75, -0.13 APE9-dihe-in -104.56, 101.78 APE8-dihe-in -62.85, 69.07 APE8-rot-na 27.65 APE67-dihe-in -73.63, -8.28 -54.79, -35.95 APE12-dist-na 999.0 APE11-dist-na 15.6242 APE10-dist-na 11.3401 APE9-dist-in 7.7723 T790M,V948R None None XRAY 2.4 0.219 0.23 A 328.0 297.0 10 30 20 10 [[712, 970]] 1.0 6wak Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKD P00533 701 1014 1210.0 ANP:1101 ATPlike Inactive DFGin 3.8807 14.6672 BLBplus -128.56, 164.59 71.9, 35.94 -89.47, 146.64 77.53, 95.38 87.93, -24.37 out-out out 13.7529 Saltbr-out 11.845 HRD-in -75.5, -62.2 82.94, 0.35 out-out-out SNCooo out-out ActLoopNT-out 6.735 ActLoopCT-out TYR APEdihe_nniai APEdist_aaao APE10-dihe-none 999.0, 999.0 APE9-dihe-none 999.0, 125.69 APE8-dihe-in -82.11, 67.25 APE8-rot-na 35.47 APE67-dihe-in -67.78, -4.44 -51.76, -45.79 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 999.0 APE9-dist-out 8.0459 T790M,V948R None None XRAY 2.4 0.219 0.23 D 328.0 297.0 17 30 16 14 [[712, 970]] 1.0 6wak Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKC P00533 701 1014 1210.0 TQA:1301 Type1.5_Front Inactive DFGin 4.1083 14.3069 BLBplus -128.74, 170.35 57.84, 42.31 -80.67, 146.74 56.84, 84.42 73.11, 52.84 out-out out 13.6867 Saltbr-out 13.1675 HRD-in -69.35, -57.7 81.97, -4.79 out-none-out SNCono none-out ActLoopNT-none 999.0 ActLoopCT-out TYR APEdihe_niiai APEdist_aaao APE10-dihe-none 999.0, -99.43 APE9-dihe-in -140.88, 118.68 APE8-dihe-in -72.34, 69.57 APE8-rot-na 41.21 APE67-dihe-in -76.32, 0.41 -56.53, -41.31 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 13.4889 APE9-dist-out 8.0417 T790M,V948R None None XRAY 2.4 0.219 0.23 C 328.0 299.0 15 30 15 15 [[712, 970]] 1.0 6wak Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor
TYR EGFR EGFR_HUMAN 6WAKB P00533 701 1020 1210.0 ANP:1101 ATPlike Inactive DFGin 5.1768 16.2307 BLBtrans -117.23, 173.55 69.28, 15.65 -59.01, 135.6 148.98, 94.52 90.59, -20.79 out-out out 13.9491 Saltbr-out 13.5428 HRD-in -74.15, -58.44 85.37, -10.97 out-out-none SNCoon out-none ActLoopNT-out 6.4805 ActLoopCT-none TYR APEdihe_niiai APEdist_aaai APE10-dihe-none 999.0, -3.86 APE9-dihe-in -108.7, 124.16 APE8-dihe-in -81.26, 64.66 APE8-rot-na 31.83 APE67-dihe-in -71.85, -2.7 -48.1, -51.02 APE12-dist-na 999.0 APE11-dist-na 999.0 APE10-dist-na 11.3657 APE9-dist-in 7.8264 T790M,V948R None None XRAY 2.4 0.219 0.23 B 328.0 316.0 4 30 26 4 [[712, 970]] 1.0 6wak Homo sapiens TYR_EGFR_HUMAN TYR 6.1e-88 300.5 3.0 259.0 257.0 854 855 856 858 860 745 762 766 834 836 835 837.0 896 884 879 878 877 876 875 874 873 791 Epidermal growth factor receptor

PDB: 6WAK — TYR EGFR_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name