PDB: 6VSN — TYR JAK2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 6VSNA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VSNA O60674 840 1132 1132.0 RG4:61201 Type1 Inactive DFGin 6.387 13.682 ABAminus -109.72, -15.97 -143.49, 135.23 -126.22, 34.01 297.74, 73.77 -69.3, -17.68 in-in in 8.481 Saltbr-in 2.897 HRD-in -79.84, -47.55 78.38, -6.15 in-in-in SNCiii in-in ActLoopNT-in 2.801 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -124.38, 157.36 APE9-dihe-in -150.13, 136.5 APE8-dihe-in -88.29, 86.0 APE8-rot-na 31.5 APE67-dihe-in -79.48, -1.84 -66.44, -27.63 APE12-dist-na 13.264 APE11-dist-na 9.454 APE10-dist-na 9.789 APE9-dist-in 7.435 None PTR1007 PTR1007 XRAY 2.5 0.192 0.252 A 308 293 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vsn TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNB O60674 842 1132 1132.0 RG4:61201 Type1 Inactive DFGin 6.533 13.616 ABAminus -117.93, -12.97 -144.23, 143.5 -132.58, 27.03 294.85, 82.1 -60.37, -24.95 in-in in 8.466 Saltbr-in 2.762 HRD-in -69.1, -47.38 74.26, -2.29 in-in-in SNCiii in-in ActLoopNT-in 2.732 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -88.77, 141.32 APE9-dihe-in -136.93, 114.67 APE8-dihe-in -78.68, 76.58 APE8-rot-na 34.47 APE67-dihe-in -78.91, -4.45 -63.01, -29.1 APE12-dist-na 13.466 APE11-dist-na 9.67 APE10-dist-na 8.649 APE9-dist-in 6.927 None PTR1007 PTR1007 XRAY 2.5 0.192 0.252 B 308 291 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vsn TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNC O60674 843 1131 1132.0 RG4:61201 Type1 Inactive DFGin 6.034 13.511 ABAminus -107.84, -22.28 -138.6, 146.61 -138.13, 17.5 291.81, 81.19 -54.12, -30.2 in-in in 8.404 Saltbr-in 2.811 HRD-in -72.34, -46.8 72.49, -7.83 in-in-in SNCiii in-in ActLoopNT-in 2.793 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.1, 144.23 APE9-dihe-in -124.87, 143.11 APE8-dihe-in -74.05, 69.35 APE8-rot-na 33.67 APE67-dihe-in -74.69, -6.91 -60.31, -31.34 APE12-dist-na 13.033 APE11-dist-na 12.562 APE10-dist-na 12.591 APE9-dist-in 7.777 None PTR1007 PTR1007 XRAY 2.5 0.192 0.252 C 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vsn TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSND O60674 843 1131 1132.0 RG4:61201 Type1 Inactive DFGin 6.309 13.563 ABAminus -113.0, -18.77 -145.19, 142.86 -134.87, 26.72 297.57, 84.55 -62.91, -20.18 in-in in 8.393 Saltbr-in 2.584 HRD-in -70.27, -45.5 73.77, -2.2 in-in-in SNCiii in-in ActLoopNT-in 2.795 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.43, 138.88 APE9-dihe-in -113.67, 149.04 APE8-dihe-in -68.65, 67.63 APE8-rot-na 29.35 APE67-dihe-in -83.91, -0.02 -57.93, -26.65 APE12-dist-na 13.214 APE11-dist-na 12.023 APE10-dist-na 12.863 APE9-dist-in 7.846 None PTR1007 PTR1007 XRAY 2.5 0.192 0.252 D 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vsn TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VSN — TYR JAK2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 6VSNA
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VSNA O60674 840 1132 1132.0 RG4:61201 Type1 Inactive DFGin 6.387 13.682 ABAminus -109.72, -15.97 -143.49, 135.23 -126.22, 34.01 297.74, 73.77 -69.3, -17.68 in-in in 8.481 Saltbr-in 2.897 HRD-in -79.84, -47.55 78.38, -6.15 in-in-in SNCiii in-in ActLoopNT-in 2.801 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -124.38, 157.36 APE9-dihe-in -150.13, 136.5 APE8-dihe-in -88.29, 86.0 APE8-rot-na 31.5 APE67-dihe-in -79.48, -1.84 -66.44, -27.63 APE12-dist-na 13.264 APE11-dist-na 9.454 APE10-dist-na 9.789 APE9-dist-in 7.435 None PTR1007 PTR1007 XRAY 2.5 0.192 0.252 A 308 293 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vsn Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNB O60674 842 1132 1132.0 RG4:61201 Type1 Inactive DFGin 6.533 13.616 ABAminus -117.93, -12.97 -144.23, 143.5 -132.58, 27.03 294.85, 82.1 -60.37, -24.95 in-in in 8.466 Saltbr-in 2.762 HRD-in -69.1, -47.38 74.26, -2.29 in-in-in SNCiii in-in ActLoopNT-in 2.732 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -88.77, 141.32 APE9-dihe-in -136.93, 114.67 APE8-dihe-in -78.68, 76.58 APE8-rot-na 34.47 APE67-dihe-in -78.91, -4.45 -63.01, -29.1 APE12-dist-na 13.466 APE11-dist-na 9.67 APE10-dist-na 8.649 APE9-dist-in 6.927 None PTR1007 PTR1007 XRAY 2.5 0.192 0.252 B 308 291 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vsn Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSNC O60674 843 1131 1132.0 RG4:61201 Type1 Inactive DFGin 6.034 13.511 ABAminus -107.84, -22.28 -138.6, 146.61 -138.13, 17.5 291.81, 81.19 -54.12, -30.2 in-in in 8.404 Saltbr-in 2.811 HRD-in -72.34, -46.8 72.49, -7.83 in-in-in SNCiii in-in ActLoopNT-in 2.793 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -68.1, 144.23 APE9-dihe-in -124.87, 143.11 APE8-dihe-in -74.05, 69.35 APE8-rot-na 33.67 APE67-dihe-in -74.69, -6.91 -60.31, -31.34 APE12-dist-na 13.033 APE11-dist-na 12.562 APE10-dist-na 12.591 APE9-dist-in 7.777 None PTR1007 PTR1007 XRAY 2.5 0.192 0.252 C 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vsn Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VSND O60674 843 1131 1132.0 RG4:61201 Type1 Inactive DFGin 6.309 13.563 ABAminus -113.0, -18.77 -145.19, 142.86 -134.87, 26.72 297.57, 84.55 -62.91, -20.18 in-in in 8.393 Saltbr-in 2.584 HRD-in -70.27, -45.5 73.77, -2.2 in-in-in SNCiii in-in ActLoopNT-in 2.795 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -66.43, 138.88 APE9-dihe-in -113.67, 149.04 APE8-dihe-in -68.65, 67.63 APE8-rot-na 29.35 APE67-dihe-in -83.91, -0.02 -57.93, -26.65 APE12-dist-na 13.214 APE11-dist-na 12.023 APE10-dist-na 12.863 APE9-dist-in 7.846 None PTR1007 PTR1007 XRAY 2.5 0.192 0.252 D 308 289 0 0 0 0 [[545, 807], [849, 1125]] 2.0 6vsn Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1 260 260 993 994 995 997 999 882 898 902 973 975 974 976 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VSN — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains - renumbered by
Uniprot PDB Alignment

Hover over column headers for tooltip help

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name