PDB: 6VS3 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VS3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VS3A O60674 843 1131 1132.0 R6V:61201 Type1 Inactive DFGin 6.1717 13.4003 ABAminus -113.69, -9.73 -145.44, 139.92 -129.95, 28.79 298.53, 82.06 -63.1, -23.05 in-in in 8.6277 Saltbr-in 2.6649 HRD-in -70.46, -47.53 70.83, 1.7 in-in-in SNCiii in-in ActLoopNT-in 2.7159 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.96, 143.74 APE9-dihe-in -124.34, 136.67 APE8-dihe-in -71.53, 71.61 APE8-rot-na 30.56 APE67-dihe-in -80.97, -2.5 -64.33, -23.02 APE12-dist-na 13.5335 APE11-dist-na 12.1921 APE10-dist-na 12.9551 APE9-dist-in 7.7308 None PTR1007 PTR1007 XRAY 2.0 0.186 0.218 A 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vs3 TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VS3B O60674 840 1132 1132.0 R6V:61201 Type1 Inactive DFGin 6.4479 13.6512 ABAminus -115.02, -9.81 -144.91, 138.32 -130.18, 30.61 296.48, 83.03 -64.54, -21.19 in-in in 8.5909 Saltbr-in 2.7581 HRD-in -72.75, -48.7 73.41, 1.11 in-in-in SNCiii in-in ActLoopNT-in 2.7917 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.71, 137.37 APE9-dihe-in -128.13, 115.26 APE8-dihe-in -80.11, 76.19 APE8-rot-na 29.15 APE67-dihe-in -81.55, -1.54 -62.24, -25.56 APE12-dist-na 13.4815 APE11-dist-na 9.5694 APE10-dist-na 8.8432 APE9-dist-in 6.8155 None PTR1007 PTR1007 XRAY 2.0 0.186 0.218 B 308.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vs3 TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VS3 — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VS3A
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VS3A O60674 843 1131 1132.0 R6V:61201 Type1 Inactive DFGin 6.1717 13.4003 ABAminus -113.69, -9.73 -145.44, 139.92 -129.95, 28.79 298.53, 82.06 -63.1, -23.05 in-in in 8.6277 Saltbr-in 2.6649 HRD-in -70.46, -47.53 70.83, 1.7 in-in-in SNCiii in-in ActLoopNT-in 2.7159 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -96.96, 143.74 APE9-dihe-in -124.34, 136.67 APE8-dihe-in -71.53, 71.61 APE8-rot-na 30.56 APE67-dihe-in -80.97, -2.5 -64.33, -23.02 APE12-dist-na 13.5335 APE11-dist-na 12.1921 APE10-dist-na 12.9551 APE9-dist-in 7.7308 None PTR1007 PTR1007 XRAY 2.0 0.186 0.218 A 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vs3 Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VS3B O60674 840 1132 1132.0 R6V:61201 Type1 Inactive DFGin 6.4479 13.6512 ABAminus -115.02, -9.81 -144.91, 138.32 -130.18, 30.61 296.48, 83.03 -64.54, -21.19 in-in in 8.5909 Saltbr-in 2.7581 HRD-in -72.75, -48.7 73.41, 1.11 in-in-in SNCiii in-in ActLoopNT-in 2.7917 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -102.71, 137.37 APE9-dihe-in -128.13, 115.26 APE8-dihe-in -80.11, 76.19 APE8-rot-na 29.15 APE67-dihe-in -81.55, -1.54 -62.24, -25.56 APE12-dist-na 13.4815 APE11-dist-na 9.5694 APE10-dist-na 8.8432 APE9-dist-in 6.8155 None PTR1007 PTR1007 XRAY 2.0 0.186 0.218 B 308.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vs3 Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VS3 — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name