PDB: 6VNK — TYR JAK2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 6VNKC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VNKA O60674 840 1132 1132.0 RXT:61201 Type1 Inactive DFGin 6.3458 13.5036 ABAminus -115.53, -9.34 -146.7, 139.79 -130.65, 29.08 297.41, 82.92 -64.51, -25.93 in-in in 8.37 Saltbr-in 2.8233 HRD-in -72.4, -46.44 73.38, -6.51 in-in-in SNCiii in-in ActLoopNT-in 2.7482 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.17, 138.86 APE9-dihe-in -125.9, 117.8 APE8-dihe-in -77.19, 70.99 APE8-rot-na 34.11 APE67-dihe-in -82.04, -0.49 -60.88, -24.48 APE12-dist-na 13.2889 APE11-dist-na 9.0776 APE10-dist-na 8.4997 APE9-dist-in 6.8874 None PTR1007 PTR1007 XRAY 2.0 0.219 0.244 A 308.0 292.0 1 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnk TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKB O60674 840 1132 1132.0 RXT:61201 Type1 Inactive DFGin 6.4843 13.4714 ABAminus -114.35, -10.36 -144.27, 138.95 -130.65, 27.3 296.72, 80.78 -63.16, -24.64 in-in in 8.645 Saltbr-in 2.9563 HRD-in -76.05, -48.13 73.42, -7.36 in-in-in SNCiii in-in ActLoopNT-in 2.8048 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.22, 137.32 APE9-dihe-in -130.36, 114.06 APE8-dihe-in -78.87, 73.36 APE8-rot-na 31.4 APE67-dihe-in -82.55, -2.95 -58.49, -25.22 APE12-dist-na 13.2589 APE11-dist-na 9.4981 APE10-dist-na 8.289 APE9-dist-in 6.9471 None PTR1007 PTR1007 XRAY 2.0 0.219 0.244 B 308.0 292.0 1 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnk TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKC O60674 843 1131 1132.0 RXT:61201 Type1 Inactive DFGin 6.298 13.4653 ABAminus -116.4, -8.39 -145.93, 138.87 -131.99, 24.75 293.4, 87.91 -62.13, -24.17 in-in in 8.433 Saltbr-in 2.7745 HRD-in -70.05, -46.67 72.0, -3.71 in-in-out SNCiio in-out ActLoopNT-in 2.6748 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -53.68, 136.82 APE9-dihe-in -128.24, 127.1 APE8-dihe-in -70.94, 70.21 APE8-rot-na 30.43 APE67-dihe-in -80.64, -2.41 -62.95, -22.96 APE12-dist-na 13.5124 APE11-dist-na 12.9301 APE10-dist-na 12.0628 APE9-dist-out 8.0852 None PTR1007 PTR1007 XRAY 2.0 0.219 0.244 C 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnk TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKD O60674 843 1131 1132.0 RXT:61201 Type1 Inactive DFGin 6.112 13.4572 ABAminus -114.41, -10.28 -145.24, 140.17 -129.26, 27.8 295.47, 88.05 -63.2, -27.61 in-in in 8.5012 Saltbr-in 2.688 HRD-in -73.35, -47.11 71.95, -9.02 in-in-in SNCiii in-in ActLoopNT-in 2.7205 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.65, 135.59 APE9-dihe-in -122.99, 135.75 APE8-dihe-in -71.71, 68.28 APE8-rot-na 32.34 APE67-dihe-in -81.87, -2.23 -61.51, -23.34 APE12-dist-na 13.283 APE11-dist-na 12.8736 APE10-dist-na 12.716 APE9-dist-in 7.7469 None PTR1007 PTR1007 XRAY 2.0 0.219 0.244 D 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnk TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VNK — TYR JAK2_HUMAN

Total number of chains: 4
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 4 100.0% 6VNKC
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VNKA O60674 840 1132 1132.0 RXT:61201 Type1 Inactive DFGin 6.3458 13.5036 ABAminus -115.53, -9.34 -146.7, 139.79 -130.65, 29.08 297.41, 82.92 -64.51, -25.93 in-in in 8.37 Saltbr-in 2.8233 HRD-in -72.4, -46.44 73.38, -6.51 in-in-in SNCiii in-in ActLoopNT-in 2.7482 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -85.17, 138.86 APE9-dihe-in -125.9, 117.8 APE8-dihe-in -77.19, 70.99 APE8-rot-na 34.11 APE67-dihe-in -82.04, -0.49 -60.88, -24.48 APE12-dist-na 13.2889 APE11-dist-na 9.0776 APE10-dist-na 8.4997 APE9-dist-in 6.8874 None PTR1007 PTR1007 XRAY 2.0 0.219 0.244 A 308.0 292.0 1 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnk Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKB O60674 840 1132 1132.0 RXT:61201 Type1 Inactive DFGin 6.4843 13.4714 ABAminus -114.35, -10.36 -144.27, 138.95 -130.65, 27.3 296.72, 80.78 -63.16, -24.64 in-in in 8.645 Saltbr-in 2.9563 HRD-in -76.05, -48.13 73.42, -7.36 in-in-in SNCiii in-in ActLoopNT-in 2.8048 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -78.22, 137.32 APE9-dihe-in -130.36, 114.06 APE8-dihe-in -78.87, 73.36 APE8-rot-na 31.4 APE67-dihe-in -82.55, -2.95 -58.49, -25.22 APE12-dist-na 13.2589 APE11-dist-na 9.4981 APE10-dist-na 8.289 APE9-dist-in 6.9471 None PTR1007 PTR1007 XRAY 2.0 0.219 0.244 B 308.0 292.0 1 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnk Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKC O60674 843 1131 1132.0 RXT:61201 Type1 Inactive DFGin 6.298 13.4653 ABAminus -116.4, -8.39 -145.93, 138.87 -131.99, 24.75 293.4, 87.91 -62.13, -24.17 in-in in 8.433 Saltbr-in 2.7745 HRD-in -70.05, -46.67 72.0, -3.71 in-in-out SNCiio in-out ActLoopNT-in 2.6748 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -53.68, 136.82 APE9-dihe-in -128.24, 127.1 APE8-dihe-in -70.94, 70.21 APE8-rot-na 30.43 APE67-dihe-in -80.64, -2.41 -62.95, -22.96 APE12-dist-na 13.5124 APE11-dist-na 12.9301 APE10-dist-na 12.0628 APE9-dist-out 8.0852 None PTR1007 PTR1007 XRAY 2.0 0.219 0.244 C 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnk Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNKD O60674 843 1131 1132.0 RXT:61201 Type1 Inactive DFGin 6.112 13.4572 ABAminus -114.41, -10.28 -145.24, 140.17 -129.26, 27.8 295.47, 88.05 -63.2, -27.61 in-in in 8.5012 Saltbr-in 2.688 HRD-in -73.35, -47.11 71.95, -9.02 in-in-in SNCiii in-in ActLoopNT-in 2.7205 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -76.65, 135.59 APE9-dihe-in -122.99, 135.75 APE8-dihe-in -71.71, 68.28 APE8-rot-na 32.34 APE67-dihe-in -81.87, -2.23 -61.51, -23.34 APE12-dist-na 13.283 APE11-dist-na 12.8736 APE10-dist-na 12.716 APE9-dist-in 7.7469 None PTR1007 PTR1007 XRAY 2.0 0.219 0.244 D 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnk Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VNK — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name