PDB: 6VNJ — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VNJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VNJA O60674 840 1132 1132.0 R5S:61201 Type1 Inactive DFGin 6.3574 13.714 ABAminus -118.92, -6.85 -149.35, 132.07 -126.54, 24.6 294.41, 81.95 -61.91, -21.92 in-in in 8.6243 Saltbr-in 2.7604 HRD-in -73.19, -45.71 72.13, -3.37 in-in-in SNCiii in-in ActLoopNT-in 2.7391 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -111.52, 135.78 APE9-dihe-in -128.55, 123.44 APE8-dihe-in -79.62, 75.87 APE8-rot-na 30.22 APE67-dihe-in -81.34, -2.92 -63.1, -25.95 APE12-dist-na 13.3984 APE11-dist-na 9.4877 APE10-dist-na 9.2245 APE9-dist-in 7.1018 None PTR1007 PTR1007 XRAY 1.9 0.185 0.211 A 308.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnj TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNJB O60674 842 1131 1132.0 R5S:61201 Type1 Inactive DFGin 6.2049 13.5669 ABAminus -116.85, -5.7 -149.84, 134.43 -128.79, 24.08 295.94, 84.61 -61.54, -23.54 in-in in 8.5923 Saltbr-in 2.5271 HRD-in -73.0, -46.01 70.61, -2.12 in-in-in SNCiii in-in ActLoopNT-in 2.7334 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -115.48, 144.02 APE9-dihe-in -116.33, 142.06 APE8-dihe-in -73.73, 71.42 APE8-rot-na 32.45 APE67-dihe-in -82.06, -3.3 -62.97, -22.66 APE12-dist-na 13.304 APE11-dist-na 12.5569 APE10-dist-na 13.498 APE9-dist-in 7.8492 None PTR1007 PTR1007 XRAY 1.9 0.185 0.211 B 308.0 290.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnj TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VNJ — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VNJA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VNJA O60674 840 1132 1132.0 R5S:61201 Type1 Inactive DFGin 6.3574 13.714 ABAminus -118.92, -6.85 -149.35, 132.07 -126.54, 24.6 294.41, 81.95 -61.91, -21.92 in-in in 8.6243 Saltbr-in 2.7604 HRD-in -73.19, -45.71 72.13, -3.37 in-in-in SNCiii in-in ActLoopNT-in 2.7391 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -111.52, 135.78 APE9-dihe-in -128.55, 123.44 APE8-dihe-in -79.62, 75.87 APE8-rot-na 30.22 APE67-dihe-in -81.34, -2.92 -63.1, -25.95 APE12-dist-na 13.3984 APE11-dist-na 9.4877 APE10-dist-na 9.2245 APE9-dist-in 7.1018 None PTR1007 PTR1007 XRAY 1.9 0.185 0.211 A 308.0 293.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnj Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNJB O60674 842 1131 1132.0 R5S:61201 Type1 Inactive DFGin 6.2049 13.5669 ABAminus -116.85, -5.7 -149.84, 134.43 -128.79, 24.08 295.94, 84.61 -61.54, -23.54 in-in in 8.5923 Saltbr-in 2.5271 HRD-in -73.0, -46.01 70.61, -2.12 in-in-in SNCiii in-in ActLoopNT-in 2.7334 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -115.48, 144.02 APE9-dihe-in -116.33, 142.06 APE8-dihe-in -73.73, 71.42 APE8-rot-na 32.45 APE67-dihe-in -82.06, -3.3 -62.97, -22.66 APE12-dist-na 13.304 APE11-dist-na 12.5569 APE10-dist-na 13.498 APE9-dist-in 7.8492 None PTR1007 PTR1007 XRAY 1.9 0.185 0.211 B 308.0 290.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vnj Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VNJ — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name