PDB: 6VNI — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VNIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VNIA O60674 842 1132 1132.0 R61:1201 Type1 Inactive DFGin 6.3724 13.8925 ABAminus -132.82, -5.88 -134.64, 102.29 -105.41, 22.74 292.04, 85.81 -67.02, -17.75 in-in in 8.4238 Saltbr-in 3.1149 HRD-in -73.15, -47.37 76.86, -9.59 in-in-in SNCiii in-in ActLoopNT-in 2.8006 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -111.58, 161.49 APE9-dihe-in -125.11, 123.14 APE8-dihe-in -78.8, 73.35 APE8-rot-na 30.02 APE67-dihe-in -81.16, -2.43 -62.36, -24.99 APE12-dist-na 12.8408 APE11-dist-na 9.2378 APE10-dist-na 10.1791 APE9-dist-in 7.2454 None PTR1007 PTR1007 XRAY 2.1 0.215 0.257 A 308.0 291.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vni TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNIB O60674 843 1131 1132.0 R61:1201 Type1 Inactive DFGin 6.2654 13.8472 ABAminus -131.4, -8.41 -135.18, 107.42 -105.53, 24.3 291.29, 84.71 -65.51, -19.14 in-in in 8.5541 Saltbr-in 2.409 HRD-in -72.62, -46.4 76.72, -7.82 in-in-out SNCiio in-out ActLoopNT-in 2.851 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -99.99, 151.02 APE9-dihe-in -125.21, 137.98 APE8-dihe-in -70.39, 70.81 APE8-rot-na 33.16 APE67-dihe-in -80.33, -2.36 -65.48, -23.28 APE12-dist-na 13.0192 APE11-dist-na 11.8194 APE10-dist-na 13.6391 APE9-dist-out 8.1584 None PTR1007 PTR1007 XRAY 2.1 0.215 0.257 B 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vni TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VNI — TYR JAK2_HUMAN

Total number of chains: 2
Active chains: 0
Total number of genes: 1
Spatial label Dihedral label Number of Chains Percent Representative
DFGin ABAminus 2 100.0% 6VNIA
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name
TYR JAK2-2 JAK2_HUMAN 6VNIA O60674 842 1132 1132.0 R61:1201 Type1 Inactive DFGin 6.3724 13.8925 ABAminus -132.82, -5.88 -134.64, 102.29 -105.41, 22.74 292.04, 85.81 -67.02, -17.75 in-in in 8.4238 Saltbr-in 3.1149 HRD-in -73.15, -47.37 76.86, -9.59 in-in-in SNCiii in-in ActLoopNT-in 2.8006 ActLoopCT-in TYR APEdihe_iiiai APEdist_aaai APE10-dihe-in -111.58, 161.49 APE9-dihe-in -125.11, 123.14 APE8-dihe-in -78.8, 73.35 APE8-rot-na 30.02 APE67-dihe-in -81.16, -2.43 -62.36, -24.99 APE12-dist-na 12.8408 APE11-dist-na 9.2378 APE10-dist-na 10.1791 APE9-dist-in 7.2454 None PTR1007 PTR1007 XRAY 2.1 0.215 0.257 A 308.0 291.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vni Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2
TYR JAK2-2 JAK2_HUMAN 6VNIB O60674 843 1131 1132.0 R61:1201 Type1 Inactive DFGin 6.2654 13.8472 ABAminus -131.4, -8.41 -135.18, 107.42 -105.53, 24.3 291.29, 84.71 -65.51, -19.14 in-in in 8.5541 Saltbr-in 2.409 HRD-in -72.62, -46.4 76.72, -7.82 in-in-out SNCiio in-out ActLoopNT-in 2.851 ActLoopCT-out TYR APEdihe_iiiai APEdist_aaao APE10-dihe-in -99.99, 151.02 APE9-dihe-in -125.21, 137.98 APE8-dihe-in -70.39, 70.81 APE8-rot-na 33.16 APE67-dihe-in -80.33, -2.36 -65.48, -23.28 APE12-dist-na 13.0192 APE11-dist-na 11.8194 APE10-dist-na 13.6391 APE9-dist-out 8.1584 None PTR1007 PTR1007 XRAY 2.1 0.215 0.257 B 308.0 289.0 0 31 31 0 [[545, 807], [849, 1125]] 2.0 6vni Homo sapiens TYR_JAK2-2_HUMAN TYR 2.9e-87 298.2 1.0 260.0 260.0 993 994 995 997 999 882 898 902 973 975 974 976.0 1036 1024 1019 1018 1017 1016 1015 1014 1013 930 Tyrosine-protein kinase JAK2

PDB: 6VNI — TYR JAK2_HUMAN

Total number of chains: 0
Active chains: 0
Total number of genes: 0
Spatial label Dihedral label Number of Chains Percent Representative
All chains
Pymol session (all) Pymol script (all)
Representatives
Pymol session (repr) Pymol script (repr)
All chains - renumbered by
Uniprot PDB Alignment
Hover over column headers for tooltip help.

Group Gene SwissprotID PDB UniprotID First_obs_res Last_obs_res Length_Unp Ligand Ligand_type Activity_label Spatial_label Phe_Glu4_dis Phe_Lys_dis Dihedral_label XDFG
φ,ψ		 DFG-Asp
φ,ψ		 DFG-Phe
φ,ψ		 DFG-Phe
χ1,χ2		 DFG-Gly
φ,ψ		 ChelixSaltbr_label Chelix_label Lys_Glu_dis Saltbr_label LysNZ_GluOE_dis HRD_label His φ,ψ Arg φ,ψ SNC_label SNCpymol_label ActLoop_label ActLoopNT_label DFG6_XHRD_dis ActLoopCT_label APEtype APEdihe_label APEdist_label APE10_dihe_label APE10 φ,ψ APE9_dihe_label APE9 φ,ψ APE8_dihe_label APE8 φ,ψ APE8_rotamer_label APE8 χ1 APE67_label APE6 φ,ψ APE7 φ,ψ APE12_dist_label APE12_DFG4_dis APE11_dist_label APE11_DFG4_dis APE10_dist_label APE10_DFG4_dis APE9_dist_label APE9_Arg_dis Chain_mut Chain_phos Modified_aa Method Resolution Rvalue FreeRvalue Chain_id ChainLen Ordered_residues DomainBreak ActLoopLength ActLoopResolvedResidues ActLoopDisorderedResidues Kinase_domains_Unp N_Kinase_domains_Unp pdb Species Kincore_name hmm Evalue Score hmmbeg hmmend hmmlen XDFGnum DFGnum PHEnum DFG4num DFG6num LYSnum GLUnum GLU4num XHRDnum ARGnum HRDnum HRDaspnum aFaspnum APEnum APE6num APE7num APE8num APE9num APE10num APE11num APE12num Hinge1num Protein_name